X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (203) 203
pyrithiamine (172) 172
rats (165) 165
male (132) 132
neurosciences (99) 99
pyrithiamine - pharmacology (82) 82
thiamine deficiency (76) 76
thiamine deficiency - chemically induced (59) 59
thiamine deficiency - metabolism (56) 56
thiamine (49) 49
thiamine deficiency - pathology (48) 48
rats, sprague-dawley (43) 43
index medicus (41) 41
thiamine deficiency - physiopathology (38) 38
thiamine - metabolism (37) 37
disease models, animal (35) 35
thiamine - antagonists & inhibitors (35) 35
brain - metabolism (34) 34
humans (33) 33
rats, inbred strains (33) 33
biochemistry & molecular biology (29) 29
thiamine deficiency - complications (29) 29
brain (28) 28
thalamus (28) 28
brain - pathology (26) 26
metabolism (25) 25
oxythiamine (25) 25
oxythiamine - pharmacology (25) 25
behavioral sciences (24) 24
neurology (24) 24
wernicke's encephalopathy (24) 24
glutamate (23) 23
rat-brain (23) 23
mice (22) 22
pyrimidines (22) 22
thiamine - pharmacology (22) 22
wernickes encephalopathy (22) 22
encephalopathy (21) 21
rodents (21) 21
pyridinium compounds - pharmacology (20) 20
research (20) 20
dependent enzymes (19) 19
physiological aspects (19) 19
pyrithiamine - toxicity (19) 19
extracellular glutamate (18) 18
time factors (18) 18
vitamin b (18) 18
induced thiamine-deficiency (17) 17
memory (17) 17
kinetics (16) 16
rat (16) 16
acetylcholine - metabolism (15) 15
brain - enzymology (15) 15
hippocampus (15) 15
pyrithiamine-induced encephalopathy (15) 15
wernicke-korsakoff syndrome (15) 15
wernicke-korsakoff-syndrome (15) 15
female (14) 14
thalamus - pathology (14) 14
antimetabolites (13) 13
article (13) 13
diencephalic amnesia (13) 13
diet (13) 13
excitotoxicity (13) 13
oxidative stress (13) 13
pharmacology & pharmacy (13) 13
amnesia (12) 12
brain - drug effects (12) 12
discrimination learning - physiology (12) 12
endocrinology & metabolism (12) 12
induced lesions (12) 12
neurons (12) 12
rats, wistar (12) 12
thiamine - analogs & derivatives (12) 12
thiamine deficiency - drug therapy (12) 12
2 experimental-models (11) 11
acetylcholine (11) 11
antimetabolites - pharmacology (11) 11
biomedicine (11) 11
brain-lesions (11) 11
clinical neurology (11) 11
glucose - metabolism (11) 11
hippocampus - metabolism (11) 11
in vitro techniques (11) 11
ketoglutarate dehydrogenase complex - metabolism (11) 11
maze learning - physiology (11) 11
performance (11) 11
pyrithiamine-induced lesions (11) 11
thalamus - drug effects (11) 11
thiamine - physiology (11) 11
thiamine pyrophosphate - metabolism (11) 11
vitamin b1 (11) 11
wernicke encephalopathy - pathology (11) 11
amino-acids (10) 10
analysis of variance (10) 10
blood-brain barrier (10) 10
brain chemistry - drug effects (10) 10
korsakoff syndrome - physiopathology (10) 10
lesions (10) 10
neurons - pathology (10) 10
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (266) 266
Italian (9) 9
Japanese (9) 9
German (6) 6
French (2) 2
Korean (1) 1
Russian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Behavioural Brain Research, ISSN 0166-4328, 03/2001, Volume 119, Issue 2, pp. 167 - 177
The present study aimed to assess the role of advanced age in the development and manifestation of thiamine deficiency using an animal model of... 
pyrithiamine
Journal Article
FEBS Letters, ISSN 0014-5793, 2003, Volume 555, Issue 3, pp. 516 - 520
Journal Article
Journal of Microbiology and Biotechnology, ISSN 1017-7825, 2019, Volume 29, Issue 2, pp. 230 - 234
Currently, the genetic modification of Aspergillus oryzae is mainly dependent on protoplast-mediated transformation (PMT). In this study, we established a dual... 
pyrithiamine | Agrobacterium tumefaciens-mediated transformation | Aspergillus oryzae | uridine/uracil auxotrophy
Journal Article
Neurotoxicology, ISSN 0161-813X, 12/2016, Volume 57, pp. 298 - 309
Prolonged vitamin B (thiamine) deficiency can lead to neurological disorders such as Wernicke’s encephalopathy and Wernicke-Korsakoff Syndrome (WKS) in humans.... 
Astrocytes | Neurodegeneration | Pyrithiamine | Endothelial cells | Microglia | CELLS | BARRIER | DISORDERS | WERNICKES ENCEPHALOPATHY | MODEL | NEUROSCIENCES | DEGENERATION | PATHOGENESIS | DIENCEPHALIC LESIONS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | ALCOHOLISM | PARKINSONS-DISEASE | Glucose Transport Proteins, Facilitative - metabolism | Brain - diagnostic imaging | Neurodegenerative Diseases - etiology | Astrocytes - pathology | Glucose Transporter Type 1 - metabolism | Male | Glial Fibrillary Acidic Protein - metabolism | Endothelial Cells - ultrastructure | Thiamine Deficiency - diagnostic imaging | Antigens, Surface - metabolism | Neurodegenerative Diseases - diagnostic imaging | Disease Models, Animal | Thiamine Deficiency - chemically induced | Pyrithiamine - toxicity | Silver Staining | Rats | Antimetabolites - toxicity | Rats, Sprague-Dawley | Astrocytes - ultrastructure | Magnetic Resonance Imaging | Animals | Thiamine Deficiency - pathology | Brain - pathology | CD11b Antigen - metabolism | Thiamine Deficiency - complications | Endothelial Cells - drug effects | Brain damage | Pyrimidines | Endothelium | Nervous system diseases | Neurons | Vitamin B1 | Brain stem | Disorders | Experiments | Blood-brain barrier | Vitamin B | Rodents | Encephalopathy | RecA protein | Thalamus | Localization | Neurological disorders | Thiamine | Glucose transporter | CD11b antigen | Nutrient deficiency | Glial fibrillary acidic protein | Vitamin deficiency | Neurological diseases | Silver | Magnetic resonance imaging | Breakage | Wernicke's encephalopathy | Diencephalon | Transporter | Integrity
Journal Article
Journal of Microbiology and Biotechnology, ISSN 1017-7825, 02/2019, Volume 29, Issue 2, pp. 230 - 234
Currently, the genetic modification of Aspergillus oryzae is mainly dependent on protoplast-mediated transformation (PMT). In this study, we established a dual... 
Agrobacterium tumefaciens-mediated transformation | Aspergillus oryzae | Pyrithiamine | Uridine/uracil auxotrophy | pyrithiamine | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RESISTANCE GENE PTRA | MICROBIOLOGY | uridine/uracil auxotrophy | 생물학
Journal Article
Metabolic Brain Disease, ISSN 0885-7490, 12/2014, Volume 29, Issue 4, pp. 1061 - 1068
Thiamine deficiency (TD) is the underlying cause of Wernicke’s encephalopathy (WE), an acute neurological disorder characterized by structural damage to key... 
Biochemistry, general | Neurology | Oxidative stress | Neurosciences | Biomedicine | Gliopathy | Excitotoxicity | Metabolic Diseases | Oncology | Vitamin B 1 | Glia | Wernicke’s encephalopathy | Vitamin B | Vitamin B-1 | EXPERIMENTAL WERNICKES ENCEPHALOPATHY | PYRITHIAMINE-INDUCED LESIONS | BLOOD-BRAIN-BARRIER | NEUROSCIENCES | ALPHA-KETOGLUTARATE DEHYDROGENASE | AMINO-ACID TRANSPORTER | MAGNETIC-RESONANCE-SPECTROSCOPY | GLIAL GLUTAMATE TRANSPORTERS | Wernicke's encephalopathy | ENDOCRINOLOGY & METABOLISM | RAT-BRAIN | ENERGY-METABOLISM | Thiamine Deficiency - chemically induced | Wernicke Encephalopathy - metabolism | Amino Acid Transport System X-AG - physiology | Neurons - pathology | Excitatory Amino Acid Transporter 2 - physiology | Nerve Tissue Proteins - physiology | Pyrithiamine - toxicity | Oxidative Stress | Wernicke Encephalopathy - etiology | Humans | Thiamine Deficiency - physiopathology | Wernicke Encephalopathy - physiopathology | Astrocytes - physiology | Thiamine Deficiency - metabolism | Animals | Biological Transport | Brain - pathology | Glutamic Acid - metabolism | Neurons - metabolism | Ketoglutarate Dehydrogenase Complex - physiology | Blood-Brain Barrier | Disease Models, Animal | Lactates | Nervous system diseases | Pyrimidines | Ligases | Pharmacy | Aquaporins | Drugstores | Glutamate | Intermediate filament proteins | Glutamine
Journal Article
Journal of General Physiology, ISSN 0022-1295, 01/2018, Volume 150, Issue 1, pp. 41 - 50
Membrane transporters of the bacterial pyridine nucleotide uptake (Pnu) family mediate the uptake of various B-type vitamins. For example, the PnuT... 
BACTERIA | PHYSIOLOGY | ECF TRANSPORTER | CRYSTAL-STRUCTURE | BIOSYNTHESIS | ABC TRANSPORTERS | MEMBRANE-PROTEINS | IDENTIFICATION | BINDING | COUPLING FACTOR TRANSPORTER | PROKARYOTES | Vitamin B1 | Usage | Phosphorylation | Pyridine | Research | Analysis | NADPH | Active transport | Pyridines | Membranes | Vitamins | Trapping | Mutagenesis | Vitamin B | Pyrithiamine | Nicotinamide | Liposomes | Diffusion | Gating | Thiamine | Cytoplasm | Crystal structure | 508
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 10/2010, Volume 115, Issue 2, pp. 333 - 342
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 10632 - 10
Accumulating evidences suggest that p53 is a key coordinator of cellular events triggered by oxidative stress often associated with the impairment in thiamine... 
OXIDATIVE STRESS | ACTIVATION | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | MECHANISMS | DEATH | P53 FUNCTION | SUPPRESSION | NEUROBLASTOMA-CELLS | DEFICIENCY | Oxidative stress | Phosphorylation | Dehydrogenases | p53 Protein | Thiamine transporter | Metabolic networks | Homeostasis | Pyruvic acid | Gene expression | Metabolism | Kinases | Thiamin pyrophosphate | Vitamin B | Pyrithiamine | Post-translation | Thiamine | Apoptosis
Journal Article
Bioscience Reports, ISSN 0144-8463, 02/2018, Volume 38, Issue 1, p. 1
Thiamine plays a very important coenzymatic and non-coenzymatic role in the regulation of basic metabolism. Thiamine diphosphate is a coenzyme of many enzymes,... 
Enzymes | Dehydrogenases | Prokaryotes | Thiamine diphosphate | Transketolase | Pyruvic acid | Vascular system | Metabolism | Drug development | Dehydrogenase | Antimetabolites | Biological activity | Organic chemistry | Eukaryotes | Vitamin B | Pyrithiamine | Oxoglutarate dehydrogenase (lipoamide) | Affinity | Coccidiosis | Chemical synthesis | Thiamine | a-Ketoglutaric acid | Cancer
Journal Article