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Journal Article
Journal of Immunological Methods, ISSN 0022-1759, 2010, Volume 358, Issue 1, pp. 93 - 103
The pattern recognition receptors (PRRs) of the innate immune system are the first defence line of the immune system. Toll-like receptors (TLRs) are the most... 
Innate immunity | Cell-based reporter gene assay | Ligand | Pyrogen | Endotoxin | Pattern recognition receptors | ACTIVATION | BIOCHEMICAL RESEARCH METHODS | LIPOPEPTIDES | HUMAN WHOLE-BLOOD | LIPOPOLYSACCHARIDES | IMMUNOLOGY | TOLL-LIKE RECEPTOR-2 | CYTOKINE PRODUCTION | CHEMICAL-STRUCTURE | INDICATORS | LINE MONO MAC-6 | NIH 3T3 Cells | Toll-Like Receptor 2 - agonists | Toll-Like Receptor 2 - genetics | Gene Expression - drug effects | Nitriles - pharmacology | Lipopeptides - pharmacology | Humans | Alkaline Phosphatase - metabolism | NF-kappa B - metabolism | Sulfones - pharmacology | Zymosan - pharmacology | Pyrogens - analysis | Receptors, Pattern Recognition - metabolism | Signal Transduction - immunology | Toll-Like Receptor 1 - agonists | Transfection | Diglycerides - pharmacology | Toll-Like Receptor 6 - genetics | Myeloid Differentiation Factor 88 - antagonists & inhibitors | Toll-Like Receptor 4 - agonists | Pyrogens - pharmacology | Toll-Like Receptor 6 - metabolism | NF-kappa B - antagonists & inhibitors | Alkaline Phosphatase - genetics | Toll-Like Receptor 1 - metabolism | Toll-Like Receptor 4 - genetics | Genes, Reporter - genetics | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Toll-Like Receptor 1 - genetics | Immunity, Innate - immunology | Animals | Immunologic Tests - methods | Signal Transduction - drug effects | Lipid A - pharmacology | Lipopolysaccharides - pharmacology | Receptors, Pattern Recognition - genetics | Ligands | Mice | Oligopeptides - pharmacology | Myeloid Differentiation Factor 88 - metabolism | Toll-Like Receptor 6 - agonists
Journal Article
Brain Research, ISSN 0006-8993, 2010, Volume 1363, pp. 93 - 106
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 12/2005, Volume 22, Issue 12, pp. 3137 - 3146
Fever is induced by a neuronal mechanism in the brain. Prostaglandin (PG) E2 acts as a pyrogenic mediator in the preoptic area (POA) probably through the EP3... 
hyperthermia | stress response | thermoregulation | sympathetic nervous system | cardiovascular regulation | Thermoregulation | Cardiovascular regulation | Stress response | Sympathetic nervous system | Hyperthermia | AMINO-ACID RECEPTORS | PERIAQUEDUCTAL GRAY | BROWN ADIPOSE-TISSUE | NEUROSCIENCES | THERMOREGULATORY FUNCTIONS | NONSHIVERING THERMOGENESIS | MEDULLARY RAPHE | SYMPATHETIC PREMOTOR NEURONS | EVOKED THERMOGENESIS | BRAIN ENDOTHELIAL-CELLS | RAPHE PALLIDUS | Muscimol - pharmacology | Rats, Wistar | Sympathetic Nervous System - drug effects | gamma-Aminobutyric Acid - metabolism | Male | Neural Pathways - physiology | Preoptic Area - cytology | Heart Rate - drug effects | Transfection - methods | Body Temperature Regulation - drug effects | Blood Pressure - drug effects | Blood Pressure - physiology | Neurons - metabolism | Pyrogens - pharmacology | Neurons - drug effects | Neural Pathways - immunology | Dinoprostone - pharmacology | Green Fluorescent Proteins - metabolism | Body Temperature Regulation - physiology | Cholera Toxin - metabolism | Dorsomedial Hypothalamic Nucleus - cytology | Adipose Tissue, Brown - physiology | Rats | Functional Laterality | Dorsomedial Hypothalamic Nucleus - metabolism | Rats, Sprague-Dawley | Receptors, Prostaglandin E, EP3 Subtype | Animals | Cell Count - methods | GABA Agonists - pharmacology | Neural Pathways - cytology | Adipose Tissue, Brown - drug effects | Models, Neurological | Receptors, Prostaglandin E - metabolism
Journal Article
Journal Article
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 05/2012, Volume 141, Issue 1, pp. 322 - 330
Puerarin is the most abundant isoflavonoid in Radix Puerariae (Gegen), which has been prescribed as a medicinal herb for treating fever in China for a long... 
NF-κB | Lipopolysaccharide | Puerarin | Macrophages | MAPK | Pyrogen | Fever | ACTIVATION | CYTOKINES | CHEMISTRY, MEDICINAL | RECOGNITION | INDUCTION | PLANT SCIENCES | NF-kappa B | INTEGRATIVE & COMPLEMENTARY MEDICINE | ENDOTOXIC FEVER | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | EXPRESSION | SUBUNIT | Phosphorylation | Isoflavones - pharmacology | Male | NF-kappa B - metabolism | RNA, Messenger - metabolism | Fever - chemically induced | Fever - physiopathology | Lipopolysaccharides | Dose-Response Relationship, Drug | Time Factors | Inflammation Mediators - metabolism | Body Temperature Regulation - drug effects | Transcription, Genetic | Antipyretics - administration & dosage | Fever - immunology | Phytotherapy | Isoflavones - administration & dosage | Macrophages - immunology | Disease Models, Animal | Cell Line | Cell Survival - drug effects | Gene Expression Regulation | Injections, Intraperitoneal | Rats | Reverse Transcriptase Polymerase Chain Reaction | Rats, Sprague-Dawley | Blotting, Western | Animals | Signal Transduction - drug effects | Fever - genetics | Macrophages - drug effects | Mice | Antipyretics - pharmacology | Fever - drug therapy | Plants, Medicinal | Mitogen-Activated Protein Kinases - metabolism | Mitogens | Transcription | Body temperature | Herbal medicines | Prostaglandin E2 | Data processing | MAP kinase | Pyrogens | Western blotting | Interleukin 6 | Polymerase chain reaction | NF- Kappa B protein | Nitric oxide | Interleukin 1 | isoflavonoids | Tumor necrosis factor- alpha
Journal Article