Natural Product Reports, ISSN 0265-0568, 3/2015, Volume 32, Issue 4, pp. 578 - 64
Covering: up to 2014 The 1 H -naphtho[2,3- c ]pyran-1-one (naphthopyranone) moiety forms the structural framework of a group of secondary metabolites that have...
CHEMISTRY, MEDICINAL | ASPERGILLUS-OCHRACEUS | PURGATIVE CRUDE DRUGS | NATURAL-PRODUCTS | TRIACYLGLYCEROL SYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEAR-MAGNETIC-RESONANCE | CHEMISTRY, ORGANIC | BLUE-GREEN PIGMENT | RESISTANT STAPHYLOCOCCUS-AUREUS | CASSIA-OBTUSIFOLIA L | ABSOLUTE-CONFIGURATION | FUNGAL METABOLITES | Naphthalenes - chemistry | Bacteria - chemistry | Lichens - chemistry | Biological Products - pharmacology | Fungi - chemistry | Pyrones - pharmacology | Biological Products - isolation & purification | Naphthalenes - isolation & purification | Naphthalenes - pharmacology | Biological Products - chemistry | Pyrones - chemistry | Pyrones - isolation & purification | Molecular Structure | Plants - chemistry
CHEMISTRY, MEDICINAL | ASPERGILLUS-OCHRACEUS | PURGATIVE CRUDE DRUGS | NATURAL-PRODUCTS | TRIACYLGLYCEROL SYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEAR-MAGNETIC-RESONANCE | CHEMISTRY, ORGANIC | BLUE-GREEN PIGMENT | RESISTANT STAPHYLOCOCCUS-AUREUS | CASSIA-OBTUSIFOLIA L | ABSOLUTE-CONFIGURATION | FUNGAL METABOLITES | Naphthalenes - chemistry | Bacteria - chemistry | Lichens - chemistry | Biological Products - pharmacology | Fungi - chemistry | Pyrones - pharmacology | Biological Products - isolation & purification | Naphthalenes - isolation & purification | Naphthalenes - pharmacology | Biological Products - chemistry | Pyrones - chemistry | Pyrones - isolation & purification | Molecular Structure | Plants - chemistry
Journal Article
Natural Product Reports, ISSN 0265-0568, 06/2005, Volume 22, Issue 3, pp. 369 - 385
The review summarises natural products containing the 2-pyrone moiety. An emphasis has been placed upon the biological activity associated with 2-pyrones,...
MARINE RED ALGA | CHEMISTRY, MEDICINAL | HIV PROTEASE INHIBITORS | TRICYCLIC PYRONE ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | ALGA PHACELOCARPUS-LABILLARDIERI | TRICHODERMA-METABOLITE 6-N-PENTYL-2H-PYRAN-2-ONE | POTENT NONPEPTIDIC INHIBITORS | PENICILLIUM SP FO-4259 | SELECTIVE ACETYLCHOLINESTERASE INHIBITORS | PANCREATIC CHOLESTEROL ESTERASE | STRUCTURE-BASED DESIGN | Anti-HIV Agents - pharmacology | Alzheimer Disease - drug therapy | Anticholesteremic Agents - chemistry | Biological Products - pharmacology | Anticholesteremic Agents - isolation & purification | Antineoplastic Agents - chemistry | Pyrones - pharmacology | Biological Products - isolation & purification | Anti-HIV Agents - chemistry | Biological Products - chemistry | Molecular Mimicry | Pyrones - chemistry | Antineoplastic Agents - isolation & purification | Pyrones - isolation & purification | Antineoplastic Agents - pharmacology | Molecular Structure | Anti-HIV Agents - isolation & purification | Anticholesteremic Agents - pharmacology
MARINE RED ALGA | CHEMISTRY, MEDICINAL | HIV PROTEASE INHIBITORS | TRICYCLIC PYRONE ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | ALGA PHACELOCARPUS-LABILLARDIERI | TRICHODERMA-METABOLITE 6-N-PENTYL-2H-PYRAN-2-ONE | POTENT NONPEPTIDIC INHIBITORS | PENICILLIUM SP FO-4259 | SELECTIVE ACETYLCHOLINESTERASE INHIBITORS | PANCREATIC CHOLESTEROL ESTERASE | STRUCTURE-BASED DESIGN | Anti-HIV Agents - pharmacology | Alzheimer Disease - drug therapy | Anticholesteremic Agents - chemistry | Biological Products - pharmacology | Anticholesteremic Agents - isolation & purification | Antineoplastic Agents - chemistry | Pyrones - pharmacology | Biological Products - isolation & purification | Anti-HIV Agents - chemistry | Biological Products - chemistry | Molecular Mimicry | Pyrones - chemistry | Antineoplastic Agents - isolation & purification | Pyrones - isolation & purification | Antineoplastic Agents - pharmacology | Molecular Structure | Anti-HIV Agents - isolation & purification | Anticholesteremic Agents - pharmacology
Journal Article
Food Chemistry, ISSN 0308-8146, 05/2015, Volume 174, pp. 306 - 309
Maltol glucoside (3-(β- -glucopyranosyloxy)-2-methyl-4H-pyran-4-one), , was isolated from a preparation of the floral nectar from the New Zealand mānuka tree (...
3-(β-d-Glucopyranosyloxy)-2-methyl-4H-pyran-4-one | Nectar | Maltol glucoside | Leptospermum scoparium | Mānuka | 3-(beta-D-Glucopyranosyloxy)-2-methyl-4H-pyran-4-one | NUTRITION & DIETETICS | FOOD SCIENCE & TECHNOLOGY | CHEMISTRY, APPLIED | Manuka | Glucosides - isolation & purification | Plant Nectar - analysis | Leptospermum - chemistry | Chromatography, High Pressure Liquid | Magnetic Resonance Spectroscopy | Pyrones - isolation & purification
3-(β-d-Glucopyranosyloxy)-2-methyl-4H-pyran-4-one | Nectar | Maltol glucoside | Leptospermum scoparium | Mānuka | 3-(beta-D-Glucopyranosyloxy)-2-methyl-4H-pyran-4-one | NUTRITION & DIETETICS | FOOD SCIENCE & TECHNOLOGY | CHEMISTRY, APPLIED | Manuka | Glucosides - isolation & purification | Plant Nectar - analysis | Leptospermum - chemistry | Chromatography, High Pressure Liquid | Magnetic Resonance Spectroscopy | Pyrones - isolation & purification
Journal Article
Phytochemistry, ISSN 0031-9422, 06/2017, Volume 138, pp. 65 - 75
Uniqueness and diversity of mango flavour across various cultivars are well known. Among various flavour metabolites lactones form an important class of aroma...
9-Lipoxygenase | Epoxide hydrolase 2 | Lactone biosynthesis | Mangifera indica | Anacardiaceae | Transient expression | PEROXYGENASE | RECOMBINANT ENZYME | BIOCHEMISTRY & MOLECULAR BIOLOGY | AROMA | FATTY-ACIDS | PLANT SCIENCES | AGROBACTERIUM | ALPHONSO MANGO | CLONING | PICHIA-PASTORIS | EXPRESSION | Aldehyde-Lyases - chemistry | Mangifera - enzymology | Mangifera - genetics | Plant Proteins - genetics | Cytochrome P-450 Enzyme System - chemistry | Pyrones - chemistry | Fatty Acids | Fruit - chemistry | Lipoxygenase - genetics | Mixed Function Oxygenases - chemistry | Epoxide Hydrolases - genetics | Lactones - chemistry | Oxidases | Enzymes | Metabolites | Analysis | Genes | Physiological aspects | Genetic research | Hydrolases | Fatty acids | Recombinant proteins
9-Lipoxygenase | Epoxide hydrolase 2 | Lactone biosynthesis | Mangifera indica | Anacardiaceae | Transient expression | PEROXYGENASE | RECOMBINANT ENZYME | BIOCHEMISTRY & MOLECULAR BIOLOGY | AROMA | FATTY-ACIDS | PLANT SCIENCES | AGROBACTERIUM | ALPHONSO MANGO | CLONING | PICHIA-PASTORIS | EXPRESSION | Aldehyde-Lyases - chemistry | Mangifera - enzymology | Mangifera - genetics | Plant Proteins - genetics | Cytochrome P-450 Enzyme System - chemistry | Pyrones - chemistry | Fatty Acids | Fruit - chemistry | Lipoxygenase - genetics | Mixed Function Oxygenases - chemistry | Epoxide Hydrolases - genetics | Lactones - chemistry | Oxidases | Enzymes | Metabolites | Analysis | Genes | Physiological aspects | Genetic research | Hydrolases | Fatty acids | Recombinant proteins
Journal Article
Natural Product Research, ISSN 1478-6419, 02/2017, Volume 31, Issue 4, pp. 387 - 396
The EtOAc extract of the liquid fermentation of Alternaria sp. Samif01, an endophytic fungus obtained from Salvia miltiorrhiza Bunge, showed antibacterial...
Alternaria sp | antioxidant | Salvia miltiorrhiza | antibacterial | Endophytic fungus | dibenzo-α-pyrones | Alternariasp | REVISION | METABOLITES | CHEMISTRY, MEDICINAL | dibenzo-alpha-pyrones | CHEMISTRY, APPLIED | DERIVATIVES | Cell Survival - drug effects | Alternaria - metabolism | Antioxidants - chemistry | Humans | Structure-Activity Relationship | Antioxidants - pharmacology | Pyrones - pharmacology | Lactones - pharmacology | Pyrones - chemistry | Anti-Bacterial Agents - chemistry | Pyrones - isolation & purification | Cell Line, Tumor | Anti-Bacterial Agents - pharmacology
Alternaria sp | antioxidant | Salvia miltiorrhiza | antibacterial | Endophytic fungus | dibenzo-α-pyrones | Alternariasp | REVISION | METABOLITES | CHEMISTRY, MEDICINAL | dibenzo-alpha-pyrones | CHEMISTRY, APPLIED | DERIVATIVES | Cell Survival - drug effects | Alternaria - metabolism | Antioxidants - chemistry | Humans | Structure-Activity Relationship | Antioxidants - pharmacology | Pyrones - pharmacology | Lactones - pharmacology | Pyrones - chemistry | Anti-Bacterial Agents - chemistry | Pyrones - isolation & purification | Cell Line, Tumor | Anti-Bacterial Agents - pharmacology
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2013, Volume 135, Issue 27, pp. 10164 - 10171
Microtubules continue to be one of the most successful anticancer drug targets and a favorite hit for many naturally occurring molecules. While two of the most...
REAGENT | OXIDATION | ALCOHOLS | TERMINAL EPOXIDES | DISCODERMOLIDE | ANALOGS | KINETIC RESOLUTION | AMINO-ACIDS | CONFIGURATION | COMPLEXES | CHEMISTRY, MULTIDISCIPLINARY | Antineoplastic Agents - chemical synthesis | Humans | Molecular Conformation | Structure-Activity Relationship | Pyrones - pharmacology | Dose-Response Relationship, Drug | HT29 Cells | Animals | Antineoplastic Agents - isolation & purification | Polyketides - chemical synthesis | Polyketides - isolation & purification | Pyrones - isolation & purification | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Porifera - chemistry | Pyrones - chemical synthesis | Drug Screening Assays, Antitumor | Polyketides - pharmacology | Polyketides | Care and treatment | Analysis | Drug targeting | Research | Chemical properties | Structure | Protein binding | Cancer
REAGENT | OXIDATION | ALCOHOLS | TERMINAL EPOXIDES | DISCODERMOLIDE | ANALOGS | KINETIC RESOLUTION | AMINO-ACIDS | CONFIGURATION | COMPLEXES | CHEMISTRY, MULTIDISCIPLINARY | Antineoplastic Agents - chemical synthesis | Humans | Molecular Conformation | Structure-Activity Relationship | Pyrones - pharmacology | Dose-Response Relationship, Drug | HT29 Cells | Animals | Antineoplastic Agents - isolation & purification | Polyketides - chemical synthesis | Polyketides - isolation & purification | Pyrones - isolation & purification | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Porifera - chemistry | Pyrones - chemical synthesis | Drug Screening Assays, Antitumor | Polyketides - pharmacology | Polyketides | Care and treatment | Analysis | Drug targeting | Research | Chemical properties | Structure | Protein binding | Cancer
Journal Article
Marine Drugs, ISSN 1660-3397, 2018, Volume 16, Issue 8, p. 285
The organic extract of the Caribbean sponge Smenospongia aurea has been shown to contain an array of novel chlorinated secondary metabolites derived from a...
Marine sponges | Secondary metabolites | Signaling molecules | Polypropionate | Smenospongia aurea | Γ-pyrone | gamma-pyrone | METABOLITES | CHEMISTRY, MEDICINAL | secondary metabolites | MOLLUSKS | marine sponges | MARINE | polypropionate | signaling molecules | Pyrones - chemistry | Animals | Magnetic Resonance Spectroscopy | Halogenation | Molecular Structure | Aquatic Organisms - chemistry | Caribbean Region | Mollusca - chemistry | Porifera - chemistry | Chemical communication | Nuclear magnetic resonance--NMR | Mollusks | Biosynthesis | Stereochemistry | Symbionts | Molecules | Organic chemistry | Marine invertebrates | Marine mollusks | Metabolites | Bacteria | Marine molluscs | Communication | γ-pyrone
Marine sponges | Secondary metabolites | Signaling molecules | Polypropionate | Smenospongia aurea | Γ-pyrone | gamma-pyrone | METABOLITES | CHEMISTRY, MEDICINAL | secondary metabolites | MOLLUSKS | marine sponges | MARINE | polypropionate | signaling molecules | Pyrones - chemistry | Animals | Magnetic Resonance Spectroscopy | Halogenation | Molecular Structure | Aquatic Organisms - chemistry | Caribbean Region | Mollusca - chemistry | Porifera - chemistry | Chemical communication | Nuclear magnetic resonance--NMR | Mollusks | Biosynthesis | Stereochemistry | Symbionts | Molecules | Organic chemistry | Marine invertebrates | Marine mollusks | Metabolites | Bacteria | Marine molluscs | Communication | γ-pyrone
Journal Article
Journal of Industrial Microbiology & Biotechnology, ISSN 1367-5435, 12/2003, Volume 30, Issue 12, pp. 721 - 731
HIV-1 integrase is a critical enzyme for replication of HIV, and its inhibition is one of the most promising new drug strategies for anti-retroviral therapy,...
Fungal metabolites | Polyketides | LifeSciences | HIV-1-integrase inhibitors | Structurally diverse natural products | DIACYLGLYCEROL ACYLTRANSFERASE | ACID | IMMUNODEFICIENCY-VIRUS INTEGRASE | GLIOCLADIUM-ROSEUM KF-1040 | polyketides | STRUCTURE ELUCIDATION | structurally diverse natural products | SELECTIVE ISOLATION | IN-VITRO | HIV-1 INTEGRASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOLOGICAL-ACTIVITY | PENICILLIUM SP | fungal metabolites | Anthraquinones - metabolism | Fungal Proteins - chemistry | Terphenyl Compounds - isolation & purification | Fatty Acids - isolation & purification | Esters - metabolism | HIV Integrase - metabolism | Penicillium - metabolism | Biphenyl Compounds - metabolism | Caffeic Acids - isolation & purification | Terpenes - chemistry | Pyrones - chemistry | Terpenes - metabolism | Esters - chemistry | Enzyme Inhibitors - chemistry | Biphenyl Compounds - chemistry | Fungal Proteins - isolation & purification | Fatty Acids - metabolism | Industrial Microbiology | Fatty Acids - chemistry | Terpenes - isolation & purification | Enzyme Inhibitors - metabolism | Biphenyl Compounds - isolation & purification | Anthraquinones - isolation & purification | Alkenes - isolation & purification | Caffeic Acids - chemistry | Aspergillus - metabolism | Fermentation | Enzyme Inhibitors - isolation & purification | Talaromyces - metabolism | Alkenes - chemistry | Terphenyl Compounds - metabolism | Terphenyl Compounds - chemistry | Esters - isolation & purification | Pyrones - isolation & purification | Caffeic Acids - metabolism | Pyrones - metabolism | Anthraquinones - chemistry | Monosaccharides - metabolism | Monosaccharides - chemistry | Sesterterpenes | Alkenes - metabolism | Fungal Proteins - metabolism | Monosaccharides - isolation & purification | Fungi
Fungal metabolites | Polyketides | LifeSciences | HIV-1-integrase inhibitors | Structurally diverse natural products | DIACYLGLYCEROL ACYLTRANSFERASE | ACID | IMMUNODEFICIENCY-VIRUS INTEGRASE | GLIOCLADIUM-ROSEUM KF-1040 | polyketides | STRUCTURE ELUCIDATION | structurally diverse natural products | SELECTIVE ISOLATION | IN-VITRO | HIV-1 INTEGRASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOLOGICAL-ACTIVITY | PENICILLIUM SP | fungal metabolites | Anthraquinones - metabolism | Fungal Proteins - chemistry | Terphenyl Compounds - isolation & purification | Fatty Acids - isolation & purification | Esters - metabolism | HIV Integrase - metabolism | Penicillium - metabolism | Biphenyl Compounds - metabolism | Caffeic Acids - isolation & purification | Terpenes - chemistry | Pyrones - chemistry | Terpenes - metabolism | Esters - chemistry | Enzyme Inhibitors - chemistry | Biphenyl Compounds - chemistry | Fungal Proteins - isolation & purification | Fatty Acids - metabolism | Industrial Microbiology | Fatty Acids - chemistry | Terpenes - isolation & purification | Enzyme Inhibitors - metabolism | Biphenyl Compounds - isolation & purification | Anthraquinones - isolation & purification | Alkenes - isolation & purification | Caffeic Acids - chemistry | Aspergillus - metabolism | Fermentation | Enzyme Inhibitors - isolation & purification | Talaromyces - metabolism | Alkenes - chemistry | Terphenyl Compounds - metabolism | Terphenyl Compounds - chemistry | Esters - isolation & purification | Pyrones - isolation & purification | Caffeic Acids - metabolism | Pyrones - metabolism | Anthraquinones - chemistry | Monosaccharides - metabolism | Monosaccharides - chemistry | Sesterterpenes | Alkenes - metabolism | Fungal Proteins - metabolism | Monosaccharides - isolation & purification | Fungi
Journal Article
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 08/2012, Volume 76, Issue 8, pp. 1452 - 1458
The KNS-16 algicidal strain was isolated from a harmful alga bloom (HAB) area and identified as Alteromonas sp. based on 16S rDNA sequencing. The KNS-16 strain...
algicidal activity | quinolone | pyrone | Alteromonas sp. KNS-16 | harmful alga blooms | Harmful alga blooms | Quinolone | Algicidal activity | Pyrone | COCHLODINIUM-POLYKRIKOIDES | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | TOXICITY | RED-TIDE | BRINE SHRIMP | PSEUDOMONAS-FLUORESCENS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | STEPHANODISCUS-HANTZSCHII | ARTEMIA-SALINA | BACTERIUM | DIATOM | ALGA | CHEMISTRY, APPLIED | Alteromonas sp KNS-16 | Quinolones - isolation & purification | Harmful Algal Bloom - drug effects | Lactones - isolation & purification | Magnetic Resonance Spectroscopy | Quinolones - pharmacology | Pyrones - pharmacology | Sequence Analysis, DNA | Lactones - pharmacology | Alteromonas - chemistry | Pyrones - chemistry | Alteromonas - genetics | Quinolones - chemistry | Mass Spectrometry | Pyrones - isolation & purification | Inhibitory Concentration 50 | RNA, Ribosomal, 16S - genetics | Harmful Algal Bloom - physiology | Lactones - chemistry
algicidal activity | quinolone | pyrone | Alteromonas sp. KNS-16 | harmful alga blooms | Harmful alga blooms | Quinolone | Algicidal activity | Pyrone | COCHLODINIUM-POLYKRIKOIDES | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | TOXICITY | RED-TIDE | BRINE SHRIMP | PSEUDOMONAS-FLUORESCENS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | STEPHANODISCUS-HANTZSCHII | ARTEMIA-SALINA | BACTERIUM | DIATOM | ALGA | CHEMISTRY, APPLIED | Alteromonas sp KNS-16 | Quinolones - isolation & purification | Harmful Algal Bloom - drug effects | Lactones - isolation & purification | Magnetic Resonance Spectroscopy | Quinolones - pharmacology | Pyrones - pharmacology | Sequence Analysis, DNA | Lactones - pharmacology | Alteromonas - chemistry | Pyrones - chemistry | Alteromonas - genetics | Quinolones - chemistry | Mass Spectrometry | Pyrones - isolation & purification | Inhibitory Concentration 50 | RNA, Ribosomal, 16S - genetics | Harmful Algal Bloom - physiology | Lactones - chemistry
Journal Article
Mycologia, ISSN 0027-5514, 07/2014, Volume 106, Issue 4, pp. 621 - 628
Indoor exposure to the spores and mycelial fragments of fungi that grow on damp building materials can result in increased non-atopic asthma and upper...
isochroman | indoor environment | koninginin | meroterpenoid | alpha pyrone | Meroterpenoid | Koninginin | Indoor environment | Alpha pyrone | Isochroman | STRAINS | STECKII | TRICHODERMA-KONINGII | GROWTH REGULATORY ACTIVITY | DIERCKX | ANDRASTINS | BIOSYNTHESIS | ALPHA-PYRONES | INHIBITORS | MYCOLOGY | PHOMENONE | Sesquiterpenes - isolation & purification | Naphthols - chemistry | Mycotoxins - isolation & purification | Naphthols - isolation & purification | Penicillium - metabolism | Respiratory Tract Infections - microbiology | Terpenes - chemistry | Pyrones - chemistry | Heterocyclic Compounds, 3-Ring - isolation & purification | Penicillium - chemistry | Humidity | Chromans - chemistry | Sesquiterpenes - chemistry | Terpenes - isolation & purification | Asthma - microbiology | Mycotoxins - chemistry | Penicillium - isolation & purification | Androstadienes - isolation & purification | Environmental Exposure | Housing | Secondary Metabolism | Canada | Chromans - isolation & purification | Androstadienes - chemistry | Heterocyclic Compounds, 3-Ring - chemistry | Pyrones - isolation & purification | Penicillium - classification | Air Pollution, Indoor - adverse effects
isochroman | indoor environment | koninginin | meroterpenoid | alpha pyrone | Meroterpenoid | Koninginin | Indoor environment | Alpha pyrone | Isochroman | STRAINS | STECKII | TRICHODERMA-KONINGII | GROWTH REGULATORY ACTIVITY | DIERCKX | ANDRASTINS | BIOSYNTHESIS | ALPHA-PYRONES | INHIBITORS | MYCOLOGY | PHOMENONE | Sesquiterpenes - isolation & purification | Naphthols - chemistry | Mycotoxins - isolation & purification | Naphthols - isolation & purification | Penicillium - metabolism | Respiratory Tract Infections - microbiology | Terpenes - chemistry | Pyrones - chemistry | Heterocyclic Compounds, 3-Ring - isolation & purification | Penicillium - chemistry | Humidity | Chromans - chemistry | Sesquiterpenes - chemistry | Terpenes - isolation & purification | Asthma - microbiology | Mycotoxins - chemistry | Penicillium - isolation & purification | Androstadienes - isolation & purification | Environmental Exposure | Housing | Secondary Metabolism | Canada | Chromans - isolation & purification | Androstadienes - chemistry | Heterocyclic Compounds, 3-Ring - chemistry | Pyrones - isolation & purification | Penicillium - classification | Air Pollution, Indoor - adverse effects
Journal Article
Journal of Natural Products, ISSN 0163-3864, 04/2015, Volume 78, Issue 4, pp. 623 - 629
A virulent strain of Diaporthe gulyae, isolated from stem cankers of sunflower and known to be pathogenic to saffron thistle, has been shown to produce both...
PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | PHOMOPSIS SP | PLANT SCIENCES | Cyclohexanols - isolation & purification | Ascomycota - chemistry | Herbicides - pharmacology | Herbicides - toxicity | Nitro Compounds - isolation & purification | Pyrones - pharmacology | Herbicides - isolation & purification | Pyrones - chemistry | Benzaldehydes - isolation & purification | Cyclohexanols - chemistry | Pyrones - isolation & purification | Carthamus - microbiology | Molecular Structure | Cyclohexanols - pharmacology | Australia | Propionates - isolation & purification
PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | PHOMOPSIS SP | PLANT SCIENCES | Cyclohexanols - isolation & purification | Ascomycota - chemistry | Herbicides - pharmacology | Herbicides - toxicity | Nitro Compounds - isolation & purification | Pyrones - pharmacology | Herbicides - isolation & purification | Pyrones - chemistry | Benzaldehydes - isolation & purification | Cyclohexanols - chemistry | Pyrones - isolation & purification | Carthamus - microbiology | Molecular Structure | Cyclohexanols - pharmacology | Australia | Propionates - isolation & purification
Journal Article
Chemical Communications, ISSN 1359-7345, 08/2013, Volume 49, Issue 62, pp. 6968 - 6970
Chemical examination of the methanolic extract from the stem bark of Daphne aurantiaca led to the isolation of two innovanoside dimers (1 and 2) with an...
NITRIC-OXIDE | CHEMISTRY, MULTIDISCIPLINARY | ANTIINFLAMMATORY ACTIVITY | Plant Extracts - chemistry | Models, Molecular | Crystallography, X-Ray | Plant Extracts - chemical synthesis | Plant Extracts - isolation & purification | Cyclobutanes - isolation & purification | Cyclobutanes - chemical synthesis | Glucosides - isolation & purification | Glucosides - chemical synthesis | Pyrones - chemistry | Daphne - chemistry | Pyrones - isolation & purification | Glucosides - chemistry | Molecular Structure | Cyclobutanes - chemistry | Pyrones - chemical synthesis | Dimerization
NITRIC-OXIDE | CHEMISTRY, MULTIDISCIPLINARY | ANTIINFLAMMATORY ACTIVITY | Plant Extracts - chemistry | Models, Molecular | Crystallography, X-Ray | Plant Extracts - chemical synthesis | Plant Extracts - isolation & purification | Cyclobutanes - isolation & purification | Cyclobutanes - chemical synthesis | Glucosides - isolation & purification | Glucosides - chemical synthesis | Pyrones - chemistry | Daphne - chemistry | Pyrones - isolation & purification | Glucosides - chemistry | Molecular Structure | Cyclobutanes - chemistry | Pyrones - chemical synthesis | Dimerization
Journal Article
Journal of Natural Products, ISSN 0163-3864, 08/2015, Volume 78, Issue 8, pp. 1809 - 1815
Fusarium fujikuroi is a member of the Gibberella fujikuroi species complex and well known for the production of gibberellins and mycotoxins including fusarins...
HYDROGEN | CHEMISTRY, MEDICINAL | ALTERNARIC ACID | BIOSYNTHESIS | THERMOCHEMISTRY | PHARMACOLOGY & PHARMACY | SPECTRA | H-1 | PLANT SCIENCES | Mycotoxins - biosynthesis | Multigene Family | Pyrones - chemistry | Fusaric Acid - biosynthesis | Fusarium - chemistry | Gibberellins - metabolism | Base Sequence | Mycotoxins - metabolism | Trichothecenes - chemistry | Molecular Structure | Fusarium - genetics | Fusarium - metabolism
HYDROGEN | CHEMISTRY, MEDICINAL | ALTERNARIC ACID | BIOSYNTHESIS | THERMOCHEMISTRY | PHARMACOLOGY & PHARMACY | SPECTRA | H-1 | PLANT SCIENCES | Mycotoxins - biosynthesis | Multigene Family | Pyrones - chemistry | Fusaric Acid - biosynthesis | Fusarium - chemistry | Gibberellins - metabolism | Base Sequence | Mycotoxins - metabolism | Trichothecenes - chemistry | Molecular Structure | Fusarium - genetics | Fusarium - metabolism
Journal Article
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Full Text
Isolation of the antibiotic pseudopyronine B and SAR evaluation of C3/C6 alkyl analogs
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 06/2017, Volume 27, Issue 12, pp. 2762 - 2765
Natural products are an abundant source of structurally diverse compounds with antibacterial activity that can be used to develop new and potent antibiotics....
Pseudopyronines | α-pyrone | Antibacterial agents | Structure activity relationship analysis | CHEMISTRY, MEDICINAL | ACID | BIOSYNTHESIS | ALPHA-PYRONES | MICROBIAL METABOLITES | CHEMISTRY, ORGANIC | PSEUDOMONAS SP F92S91 | alpha-pyrone | DISCOVERY | Gram-Positive Bacteria - drug effects | Structure-Activity Relationship | Anti-Bacterial Agents - isolation & purification | Pyrones - pharmacology | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Gram-Negative Bacteria - drug effects | Pyrones - chemistry | Anti-Bacterial Agents - chemistry | Pyrones - isolation & purification | Anti-Bacterial Agents - pharmacology | Molecular Structure | Pseudomonas - chemistry
Pseudopyronines | α-pyrone | Antibacterial agents | Structure activity relationship analysis | CHEMISTRY, MEDICINAL | ACID | BIOSYNTHESIS | ALPHA-PYRONES | MICROBIAL METABOLITES | CHEMISTRY, ORGANIC | PSEUDOMONAS SP F92S91 | alpha-pyrone | DISCOVERY | Gram-Positive Bacteria - drug effects | Structure-Activity Relationship | Anti-Bacterial Agents - isolation & purification | Pyrones - pharmacology | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Gram-Negative Bacteria - drug effects | Pyrones - chemistry | Anti-Bacterial Agents - chemistry | Pyrones - isolation & purification | Anti-Bacterial Agents - pharmacology | Molecular Structure | Pseudomonas - chemistry
Journal Article
Natural Product Research, ISSN 1478-6419, 09/2014, Volume 28, Issue 17, pp. 1388 - 1392
Seven known metabolites, dianhydro-aurasperone C (1), isoaurasperone A (2), fonsecinone A (3), asperpyrone A (4), asperazine (5), rubrofusarin B (6) and...
endophytic fungus | Aspergillus sp | antimicrobial bioactivity | naphtho-γ-pyrone polyketide | phytopathogenic fungi | naphtho-g-pyrone polyketide | CHEMISTRY, MEDICINAL | NIGER | NITRILES | CHEMISTRY, APPLIED | NAPHTHO-GAMMA-PYRONES | naphtho-gamma-pyrone polyketide | FUMIGATUS | Gibberella - drug effects | Nitriles - pharmacology | Colletotrichum - drug effects | Escherichia coli - drug effects | Aspergillus - chemistry | Melia azedarach - microbiology | Antifungal Agents - chemistry | Piperazines - chemistry | Indoles - isolation & purification | Magnaporthe - drug effects | Pyrones - pharmacology | Naphthalenes - isolation & purification | Microbial Sensitivity Tests | Pyrones - chemistry | Anti-Bacterial Agents - chemistry | Bacillus cereus - drug effects | Nuclear Magnetic Resonance, Biomolecular | Indoles - pharmacology | Chromones - pharmacology | Antifungal Agents - pharmacology | Naphthalenes - chemistry | Alternaria - drug effects | Anti-Bacterial Agents - isolation & purification | Nitriles - isolation & purification | Piperazines - isolation & purification | Piperazines - pharmacology | Naphthalenes - pharmacology | Antifungal Agents - isolation & purification | Chromones - chemistry | Botrytis - drug effects | Nitriles - chemistry | Pyrones - isolation & purification | Chromones - isolation & purification | Anti-Bacterial Agents - pharmacology | Staphylococcus aureus - drug effects | Indoles - chemistry | Bacillus subtilis - drug effects
endophytic fungus | Aspergillus sp | antimicrobial bioactivity | naphtho-γ-pyrone polyketide | phytopathogenic fungi | naphtho-g-pyrone polyketide | CHEMISTRY, MEDICINAL | NIGER | NITRILES | CHEMISTRY, APPLIED | NAPHTHO-GAMMA-PYRONES | naphtho-gamma-pyrone polyketide | FUMIGATUS | Gibberella - drug effects | Nitriles - pharmacology | Colletotrichum - drug effects | Escherichia coli - drug effects | Aspergillus - chemistry | Melia azedarach - microbiology | Antifungal Agents - chemistry | Piperazines - chemistry | Indoles - isolation & purification | Magnaporthe - drug effects | Pyrones - pharmacology | Naphthalenes - isolation & purification | Microbial Sensitivity Tests | Pyrones - chemistry | Anti-Bacterial Agents - chemistry | Bacillus cereus - drug effects | Nuclear Magnetic Resonance, Biomolecular | Indoles - pharmacology | Chromones - pharmacology | Antifungal Agents - pharmacology | Naphthalenes - chemistry | Alternaria - drug effects | Anti-Bacterial Agents - isolation & purification | Nitriles - isolation & purification | Piperazines - isolation & purification | Piperazines - pharmacology | Naphthalenes - pharmacology | Antifungal Agents - isolation & purification | Chromones - chemistry | Botrytis - drug effects | Nitriles - chemistry | Pyrones - isolation & purification | Chromones - isolation & purification | Anti-Bacterial Agents - pharmacology | Staphylococcus aureus - drug effects | Indoles - chemistry | Bacillus subtilis - drug effects
Journal Article
Future Medicinal Chemistry, ISSN 1756-8919, 09/2017, Volume 9, Issue 14, pp. 1631 - 1648
The last three decades have shown that the fungi can be 'biofactories' of novel, bioactive secondary metabolites that produce numerous natural products with...
biodiversity | polyketides | fungi | chemodiversity | SECONDARY METABOLITES | DEPSIDONES | CHEMISTRY, MEDICINAL | NATURAL-PRODUCTS | ANTHRAQUINONE DERIVATIVES | IDENTIFICATION | CYTOTOXIC METABOLITES | XANTHONES | BIOACTIVE METABOLITES | ENDOPHYTIC FUNGUS | A-D | Depsides - isolation & purification | Anti-Infective Agents - isolation & purification | Gram-Positive Bacteria - drug effects | Anti-Infective Agents - pharmacology | Benzophenones - pharmacology | Polyketides - chemistry | Coumarins - chemistry | Fungi - metabolism | Xanthones - pharmacology | Pyrones - pharmacology | Lactones - pharmacology | Depsides - pharmacology | Coumarins - isolation & purification | Pyrones - chemistry | Anti-Infective Agents - chemistry | Benzophenones - isolation & purification | Lactones - chemistry | Xanthones - chemistry | Benzophenones - chemistry | Xanthones - isolation & purification | Lactones - isolation & purification | Anthraquinones - isolation & purification | Depsides - chemistry | Fungi - chemistry | Coumarins - pharmacology | Gram-Negative Bacteria - drug effects | Polyketides - isolation & purification | Pyrones - isolation & purification | Anthraquinones - pharmacology | Anthraquinones - chemistry | Polyketides - pharmacology | Index Medicus
biodiversity | polyketides | fungi | chemodiversity | SECONDARY METABOLITES | DEPSIDONES | CHEMISTRY, MEDICINAL | NATURAL-PRODUCTS | ANTHRAQUINONE DERIVATIVES | IDENTIFICATION | CYTOTOXIC METABOLITES | XANTHONES | BIOACTIVE METABOLITES | ENDOPHYTIC FUNGUS | A-D | Depsides - isolation & purification | Anti-Infective Agents - isolation & purification | Gram-Positive Bacteria - drug effects | Anti-Infective Agents - pharmacology | Benzophenones - pharmacology | Polyketides - chemistry | Coumarins - chemistry | Fungi - metabolism | Xanthones - pharmacology | Pyrones - pharmacology | Lactones - pharmacology | Depsides - pharmacology | Coumarins - isolation & purification | Pyrones - chemistry | Anti-Infective Agents - chemistry | Benzophenones - isolation & purification | Lactones - chemistry | Xanthones - chemistry | Benzophenones - chemistry | Xanthones - isolation & purification | Lactones - isolation & purification | Anthraquinones - isolation & purification | Depsides - chemistry | Fungi - chemistry | Coumarins - pharmacology | Gram-Negative Bacteria - drug effects | Polyketides - isolation & purification | Pyrones - isolation & purification | Anthraquinones - pharmacology | Anthraquinones - chemistry | Polyketides - pharmacology | Index Medicus
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 07/2018, Volume 23, Issue 8, p. 1907
Piper methysticum (kava) root is known to possess promising weed suppressing activity. The present study was conducted to search for potent plant growth...
Piper methysticum L | flavanone | growth inhibitor | natural herbicide | Raphanus sativus | kavalactone | ALLELOCHEMICALS | ANTIOXIDANT ACTIVITIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | LEAVES | PERS. BL BURTT | KAVA HEPATOTOXICITY | ALPINIA-ZERUMBET | IDENTIFICATION | PYRONES | CHEMISTRY, MULTIDISCIPLINARY | LACTONES | RM SM | Flavanones - isolation & purification | Plant Extracts - chemistry | Plant Weeds - growth & development | Gas Chromatography-Mass Spectrometry | Solvents - chemistry | Acetates - chemistry | Plant Growth Regulators - classification | Lactones - pharmacology | Lactones - classification | Molecular Structure | Weed Control - methods | Kava - metabolism | Plant Growth Regulators - isolation & purification | Plant Weeds - drug effects | Plant Roots - metabolism | Lactones - isolation & purification | Flavanones - pharmacology | Herbicides - classification | Kava - chemistry | Herbicides - pharmacology | Flavanones - classification | Herbicides - isolation & purification | Raphanus - growth & development | Raphanus - drug effects | Plant Roots - chemistry | Plant Growth Regulators - pharmacology | Plants, Medicinal | Medicinal plants | Spectroscopy | Nuclear magnetic resonance--NMR | Puri
Piper methysticum L | flavanone | growth inhibitor | natural herbicide | Raphanus sativus | kavalactone | ALLELOCHEMICALS | ANTIOXIDANT ACTIVITIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | LEAVES | PERS. BL BURTT | KAVA HEPATOTOXICITY | ALPINIA-ZERUMBET | IDENTIFICATION | PYRONES | CHEMISTRY, MULTIDISCIPLINARY | LACTONES | RM SM | Flavanones - isolation & purification | Plant Extracts - chemistry | Plant Weeds - growth & development | Gas Chromatography-Mass Spectrometry | Solvents - chemistry | Acetates - chemistry | Plant Growth Regulators - classification | Lactones - pharmacology | Lactones - classification | Molecular Structure | Weed Control - methods | Kava - metabolism | Plant Growth Regulators - isolation & purification | Plant Weeds - drug effects | Plant Roots - metabolism | Lactones - isolation & purification | Flavanones - pharmacology | Herbicides - classification | Kava - chemistry | Herbicides - pharmacology | Flavanones - classification | Herbicides - isolation & purification | Raphanus - growth & development | Raphanus - drug effects | Plant Roots - chemistry | Plant Growth Regulators - pharmacology | Plants, Medicinal | Medicinal plants | Spectroscopy | Nuclear magnetic resonance--NMR | Puri