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Journal of the National Cancer Institute, ISSN 0027-8874, 11/2011, Volume 103, Issue 22, pp. 1665 - 1675
Recent advances in tumor biology have made remarkable achievements in the development of therapy for metastatic castrate-resistant prostate cancer. These... 
GROWTH-FACTOR RECEPTOR | CONTROLLED-TRIAL | ANTIANGIOGENIC THERAPY | ONCOLOGY | RANDOMIZED PHASE-II | BONE METASTASES | C-MET | SIPULEUCEL-T APC8015 | ABIRATERONE ACETATE | TUMOR MICROENVIRONMENT | ANGIOGENESIS INHIBITION | Cancer Vaccines - pharmacology | Humans | Male | Antineoplastic Agents - therapeutic use | Bevacizumab | Prostatic Neoplasms - immunology | RANK Ligand - pharmacology | Receptors, Androgen - drug effects | Treatment Failure | Prostatic Neoplasms - drug therapy | Phenylthiohydantoin - pharmacology | Tumor Microenvironment - drug effects | Dasatinib | Antibodies, Monoclonal - pharmacology | Angiogenesis Inhibitors - pharmacology | Clusterin - pharmacology | Pyrimidines - pharmacology | Denosumab | Prostate-Specific Antigen - blood | Orchiectomy | Signal Transduction - drug effects | Anilides - pharmacology | Mice | Receptor Cross-Talk - drug effects | Endothelin-1 - antagonists & inhibitors | Immunotherapy - methods | Taxoids - pharmacology | Ipilimumab | Tissue Extracts - pharmacology | Bone Remodeling - drug effects | Pyrrolidines - pharmacology | Antibodies, Monoclonal, Humanized - pharmacology | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Molecular Targeted Therapy - methods | Prostatic Neoplasms - pathology | Antineoplastic Agents, Hormonal - pharmacology | Androstenols - pharmacology | Androstenes | Clinical Trials as Topic | Mice, SCID | Phenylthiohydantoin - analogs & derivatives | Biomarkers, Tumor - blood | Xenograft Model Antitumor Assays | Cancer Vaccines - immunology | Pyrroles - pharmacology | Animals | RANK Ligand - antagonists & inhibitors | Pyridines - pharmacology | Thiazoles - pharmacology | Immune response | Development and progression | Cellular signal transduction | Research | Drug therapy | Health aspects | Prostate cancer | Risk factors | Review
Journal Article
Neuropsychopharmacology (New York, N.Y.), ISSN 1740-634X, 2008, Volume 34, Issue 3, pp. 681 - 697
Psychopharmacological studies have implicated the mesolimbic dopamine (DA) system in the mediation of cost/benefit evaluations about delay or effort-related... 
Discounting | Gambling | Amphetamine | Parkinson's disease | receptors | D-1 RECEPTOR | PSYCHIATRY | discounting | amphetamine | gambling | NEUROCHEMICAL PROFILE | NORMAL VOLUNTEERS | NEUROSCIENCES | VENTROMEDIAL PREFRONTAL CORTEX | D-2 receptors | IMPULSIVE BEHAVIOR | D-3 receptors | PHARMACOLOGY & PHARMACY | RECEPTOR GENE | D-AMPHETAMINE | PROBABILISTIC REINFORCEMENT | WORKING-MEMORY | PARKINSONS-DISEASE | Receptors, Dopamine D4 - agonists | Rats, Long-Evans | Decision Making - drug effects | Risk | Receptors, Dopamine D4 - antagonists & inhibitors | Pyrrolidines - pharmacology | Conditioning, Operant - drug effects | Receptors, Dopamine D1 - agonists | Behavior, Animal - drug effects | Benzamides - pharmacology | Benzopyrans - pharmacology | Receptors, Dopamine D3 - antagonists & inhibitors | Oxazines - pharmacology | Receptors, Dopamine D1 - antagonists & inhibitors | Dopamine Agonists - pharmacology | Dextroamphetamine - pharmacology | Receptors, Dopamine D2 - agonists | Rats | Behavior, Animal - physiology | Bromocriptine - pharmacology | Benzazepines - pharmacology | Piperazines - pharmacology | Naphthalenes - pharmacology | Receptors, Dopamine D3 - agonists | Reinforcement Schedule | Pyrroles - pharmacology | Animals | Dopamine Antagonists - pharmacology | Decision Making - physiology | Pyridines - pharmacology | Dopamine D2 Receptor Antagonists | Salicylamides - pharmacology
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2004, Volume 24, Issue 36, pp. 7821 - 7828
Journal Article
Neuropharmacology, ISSN 0028-3908, 2014, Volume 87, pp. 206 - 213
There has been a dramatic rise in the abuse of synthetic cathinones known as “bath salts,” including 3,4-methylenedioxypyrovalerone (MDPV), an analog linked to... 
3,4-Methylenedioxypyrovalerone | Synthetic cathinones | α-PVP | Locomotor activity | Functional observational battery | Monoamine transporter | ANALOGS | RATS | LOCOMOTOR-ACTIVITY | MEPHEDRONE | CATHINONE DERIVATIVES | MONOAMINE TRANSPORTERS | NEUROSCIENCES | INTOXICATION | alpha-PVP | IN-VITRO | DOPAMINE | PHARMACOLOGY & PHARMACY | 2ND-GENERATION LEGAL HIGHS | Dopamine Plasma Membrane Transport Proteins - metabolism | Synaptosomes - drug effects | Central Nervous System Stimulants - pharmacology | Motor Activity - drug effects | Male | Synaptosomes - metabolism | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Benzodioxoles - chemistry | Locomotion - drug effects | Designer Drugs - pharmacology | Catecholamine Plasma Membrane Transport Proteins - metabolism | Brain - physiopathology | Catecholamine Plasma Membrane Transport Proteins - antagonists & inhibitors | Benzazepines - pharmacology | Random Allocation | Pyrrolidines - chemistry | Rats, Sprague-Dawley | Mice, Inbred ICR | Brain - drug effects | Designer Drugs - chemistry | Animals | Dopamine Antagonists - pharmacology | Central Nervous System Stimulants - chemistry | Norepinephrine Plasma Membrane Transport Proteins - metabolism | Street Drugs - pharmacology | Benzodioxoles - pharmacology | RNA-Binding Proteins - metabolism | Street Drugs - chemistry | Bath products | Resveratrol | monoamine transporter | locomotor activity | 3,4-methylenedioxypyrovalerone | functional observational battery | synthetic cathinones
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 08/2003, Volume 93, Issue 4, pp. 311 - 320
ABSTRACT—Homocysteine (Hcy) is an independent risk factor for cardiovascular disease. Monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) are... 
Monocyte chemoattractant protein-1 | Monocytes | Homocysteine | Interleukin-8 | Atherosclerosis | homocysteine | atherosclerosis | monocytes | ENDOTHELIAL-CELL INJURY | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | OXIDANT STRESS | monocyte chemoattractant protein-1 | RISK FACTOR | PLASMA HOMOCYST(E)INE | interleukin-8 | VASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | ATHEROMATOUS PLAQUES | HEMATOLOGY | NF-KAPPA-B | T-LYMPHOCYTES | Interleukin-8 - genetics | Reactive Oxygen Species - metabolism | Chemokine CCL2 - secretion | Monocytes - cytology | Humans | Dimethyl Sulfoxide - pharmacology | Monocytes - metabolism | RNA, Messenger - metabolism | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Thiocarbamates - pharmacology | Chromans - pharmacology | Time Factors | Homocysteine - pharmacology | Indoles - pharmacology | Interleukin-8 - secretion | Flavonoids - pharmacology | RNA, Messenger - drug effects | RNA, Messenger - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Chemokine CCL2 - genetics | Imidazoles - pharmacology | Tyrphostins - pharmacology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Sulfonamides - pharmacology | Naphthalenes - pharmacology | Gene Expression Regulation - drug effects | Monocytes - drug effects | Genistein - pharmacology | Pyridines - pharmacology | Thiazoles - pharmacology | Thiazolidinediones
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2008, Volume 28, Issue 14, pp. 3769 - 3780
Journal Article
Neuropsychopharmacology (New York, N.Y.), ISSN 1740-634X, 2012, Volume 38, Issue 4, pp. 552 - 562
...) is a growing public health concern, yet little is known about their pharmacology. Here, we evaluated the effects of MDPV and related drugs using molecular, cellular, and whole-animal methods... 
cathinone | monoamine transporter | uptake blocker | dopamine | designer drug | NOREPINEPHRINE | PSYCHIATRY | DOPAMINE OVERFLOW | LOCOMOTOR-ACTIVITY | MEPHEDRONE | MONOAMINE TRANSPORTERS | NEUROSCIENCES | NUCLEUS-ACCUMBENS | LEGAL HIGHS | DRUGS | PHARMACOLOGY & PHARMACY | D-AMPHETAMINE | UPTAKE INHIBITORS | Motor Activity - physiology | Humans | Motor Activity - drug effects | Male | Corpus Striatum - metabolism | Pyrrolidines - pharmacology | Salts - chemistry | Salts - pharmacology | Psychotropic Drugs - pharmacology | HEK293 Cells | Benzodioxoles - chemistry | Dopamine - metabolism | Organ Culture Techniques | Cocaine - chemistry | Designer Drugs - pharmacology | Mice, Inbred C57BL | Rats | Psychotropic Drugs - chemistry | Random Allocation | Pyrrolidines - chemistry | Rats, Sprague-Dawley | Cocaine - pharmacology | Designer Drugs - chemistry | Animals | Corpus Striatum - drug effects | Mice | Benzodioxoles - pharmacology | Neurochemistry | Brain | Drug abuse | Salts | Dopamine | Intravenous administration | Brain slice preparation | Catecholamines | Data processing | Pharmacology | Nucleus accumbens | Side effects | Tachycardia | Monoamine transporter | Neostriatum | Cocaine | Locomotor activity | Neurotransmission | Public health | addiction & Substance Abuse | blocker | catecholamines | releaser | designer drugs | neuropharmacology | transporter | Original | Psychostimulants
Journal Article
Journal Article
Journal of Endodontics, ISSN 0099-2399, 2014, Volume 40, Issue 7, pp. 937 - 942
Abstract Introduction Biodentine (Septodont, Saint-Maur-des-Fossès, France), a new tricalcium silicate cement formulation, has been introduced as a bioactive... 
Endocrinology & Metabolism | Dentistry | Biodentine | biosilicate cement | calcium-/calmodulin-dependent protein kinase II | mitogen-activated protein kinase pathway | pathway | human dental pulp stem cells | nuclear factor-kappa B pathway | BONE-MARROW | MINERAL TRIOXIDE AGGREGATE | IN-VITRO | REPAIR | DENTISTRY, ORAL SURGERY & MEDICINE | NF-KAPPA-B | EXPRESSION | SILICATE | Nitriles - pharmacology | Humans | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - drug effects | Integrin-Binding Sialoprotein - analysis | Extracellular Matrix Proteins - analysis | Pyrrolidines - pharmacology | Young Adult | Thiocarbamates - pharmacology | Phosphoproteins - analysis | Alkaline Phosphatase - analysis | Adult | Cell Culture Techniques | Pulp Capping and Pulpectomy Agents - pharmacology | Osteocalcin - analysis | Calcium Compounds - pharmacology | Silicates - pharmacology | Butadienes - pharmacology | NF-kappa B - antagonists & inhibitors | Dental Pulp - cytology | Dental Pulp - drug effects | Imidazoles - pharmacology | Sulfonamides - pharmacology | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - antagonists & inhibitors | Anthracenes - pharmacology | MAP Kinase Signaling System - drug effects | Signal Transduction - drug effects | Cell Differentiation - drug effects | Adolescent | Odontoblasts - drug effects | Stem Cells - drug effects | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Sialoglycoproteins - analysis | Benzylamines - pharmacology | NF-kappa B - drug effects | Cell differentiation | Mitogens | Protein kinases | Calmodulin | Stem cells
Journal Article
The AAPS Journal, ISSN 1550-7416, 4/2013, Volume 15, Issue 2, pp. 395 - 406
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1524-4636, 2010, Volume 30, Issue 7, pp. 1407 - 1414
Objective-Endothelial cell senescence is an important contributor to vascular aging and is increased under diabetic conditions. Here we investigated whether... 
endothelium | APOPTOSIS | TRANSCRIPTION | glucagon-like peptide 1 | ATHEROSCLEROSIS | diabetes mellitus | ZUCKER RAT | NEPHROPATHY | UMCG Approved | senescence | reactive oxygen species | CARDIOVASCULAR-DISEASE | NITRIC-OXIDE | DYSFUNCTION | GLP-1 RECEPTOR | DIABETIC FATTY RATS | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Diabetes Mellitus - enzymology | Diabetes Mellitus - pathology | Heme Oxygenase-1 - metabolism | Oxidants - pharmacology | Reactive Oxygen Species - metabolism | Nitriles - pharmacology | Humans | Cellular Senescence - drug effects | Male | Phosphatidylinositol 3-Kinases - metabolism | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Proto-Oncogene Proteins c-akt - metabolism | Cyclic AMP - metabolism | Adamantane - analogs & derivatives | Disease Models, Animal | Cyclic AMP-Dependent Protein Kinases - metabolism | Adamantane - pharmacology | Glucagon-Like Peptide 1 - metabolism | Signal Transduction | Cells, Cultured | Diabetes Mellitus - drug therapy | Hydrogen Peroxide - pharmacology | Rats | Receptors, Glucagon - metabolism | Hypoglycemic Agents - pharmacology | Peptides - pharmacology | Rats, Zucker | Animals | Glucagon-Like Peptide-1 Receptor | Cyclic AMP Response Element-Binding Protein - metabolism | NAD(P)H Dehydrogenase (Quinone) - metabolism | Venoms - pharmacology | DNA Damage | Enzyme Activation | Oxidative Stress - drug effects | Endothelial Cells - pathology | Endothelial Cells - enzymology | Endothelial Cells - drug effects
Journal Article
Psychopharmacology, ISSN 0033-3158, 9/2015, Volume 232, Issue 17, pp. 3249 - 3258
Journal Article