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Journal Article
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 498, Issue 7452, pp. 109 - 112
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2004, Volume 24, Issue 36, pp. 7779 - 7788
Mitochondria-produced reactive oxygen species (ROS) are thought to contribute to cell death caused by a multitude of pathological conditions. The molecular... 
Lipoamide dehydrogenase | Mitochondria | Reactive oxygen species | Ketoglutarate dehydrogenase | Alzheimer | Parkinson | PERMEABILITY TRANSITION PORE | RESPIRATORY-CHAIN | 2-OXOGLUTARATE DEHYDROGENASE | mitochondria | ketoglutarate dehydrogenase | RAT-LIVER MITOCHONDRIA | RADICAL GENERATION | lipoamide dehydrogenase | NEUROSCIENCES | NICOTINAMIDE ADENINE-DINUCLEOTIDE | BRAIN MITOCHONDRIA | PIG-HEART | reactive oxygen species | HYDROGEN-PEROXIDE | Mitochondria - enzymology | Electron Transport - drug effects | Reactive Oxygen Species - metabolism | Ubiquinone - analysis | Intracellular Membranes - physiology | Ketoglutarate Dehydrogenase Complex - metabolism | Antimycin A - pharmacology | Prosencephalon - enzymology | Oligomycins - pharmacology | Rotenone - pharmacology | Superoxides - metabolism | Electron Transport - physiology | NADP - metabolism | Ketoglutaric Acids - metabolism | NAD - metabolism | Pyruvate Dehydrogenase Complex - metabolism | Coenzymes | Electron Transport Complex I - antagonists & inhibitors | Superoxide Dismutase - pharmacology | Oxidation-Reduction | Dihydrolipoamide Dehydrogenase - deficiency | Ubiquinone - analogs & derivatives | Antimycin A - analogs & derivatives | Prosencephalon - ultrastructure | Rats | Mitochondria - drug effects | Rats, Sprague-Dawley | Adenosine Diphosphate - pharmacology | Hydrogen Peroxide - metabolism | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Membrane Potentials | Succinic Acid - metabolism | Dihydrolipoamide Dehydrogenase - genetics | Dihydrolipoamide Dehydrogenase - metabolism | Mice | Index Medicus
Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2015, Volume 467, Issue 2, pp. 271 - 280
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2018, Volume 50, Issue 2, pp. 219 - 228
The mechanisms by which mitochondrial metabolism supports cancer anabolism remain unclear. Here, we found that genetic and pharmacological inactivation of... 
OXIDATIVE STRESS | METABOLIC SWITCH | EPITHELIAL-CELLS | TCA CYCLE | STEROL REGULATORY ELEMENT | MITOCHONDRIA | GENETICS & HEREDITY | ZINC INHIBITION | LIPOPROTEIN RECEPTOR PROMOTER | NUCLEAR-PROTEIN | HISTONE ACETYLATION | Pyruvate Dehydrogenase Complex - metabolism | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - pathology | Humans | Protein Processing, Post-Translational - genetics | Cells, Cultured | Cytoplasm - metabolism | Male | Cytoplasm - pathology | Pyruvate Dehydrogenase (Lipoamide) - metabolism | Mice, Knockout | Cell Compartmentation - physiology | Pyruvate Dehydrogenase Complex - physiology | Animals | Cell Nucleus - metabolism | Prostatic Neoplasms - genetics | Cell Nucleus - genetics | Lipogenesis - genetics | Cell Nucleus - pathology | Cell Line, Tumor | Cytoplasm - genetics | Mice | Pyruvate Dehydrogenase (Lipoamide) - genetics | Phosphatases | Pyruvate dehydrogenase complex | Genetic aspects | Research | Genetic transcription | Diagnosis | Prostate cancer | Animal models | Phosphorylation | Dehydrogenases | Xenotransplantation | Pyruvic acid | Lipids | Biosynthesis | Regulatory sequences | Kinases | Dehydrogenase | Inactivation | Datasets | Proteins | Mitochondria | Cell growth | Xenografts | Tumorigenesis | Acetylation | Lipogenesis | Deactivation | Pyruvate dehydrogenase (lipoamide) | Pharmacology | Metabolism | Gene expression | Citric acid | Respiration | Prostate | Cancer | Apoptosis | Tumors | Index Medicus
Journal Article