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Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 329, Issue 5998, pp. 1492 - 1499
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 01/2014, Volume 124, Issue 1, pp. 367 - 384
There is a considerable resurgence of interest in the role of aerobic glycolysis in cancer; however, increased glycolysis is frequently viewed as a consequence... 
MEDICINE, RESEARCH & EXPERIMENTAL | GENE-EXPRESSION SIGNATURE | SOLUBLE ADENYLYL-CYCLASE | VIRUS-TRANSFORMED CELLS | GLUCOSE-METABOLISM | PYRUVATE-KINASE M2 | EPIDERMAL-GROWTH-FACTOR | RECONSTITUTED BASEMENT-MEMBRANE | EXTRACELLULAR-MATRIX | HUMAN BREAST CELLS | MAMMARY EPITHELIAL-CELLS | Up-Regulation | Humans | Glucose Transporter Type 3 - metabolism | Acetylglucosamine - metabolism | Breast Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | Guanine Nucleotide Exchange Factors - metabolism | Female | Membrane Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Telomere-Binding Proteins - metabolism | Oncogenes | Second Messenger Systems | Cell Line | Oxygen Consumption | Biosynthetic Pathways | Glycosylation | MAP Kinase Kinase Kinases - metabolism | Adenylyl Cyclases - metabolism | Cell Transformation, Neoplastic - metabolism | Integrin beta1 - metabolism | Phenotype | Carrier Proteins - metabolism | Thyroid Hormones - metabolism | Glucose - metabolism | Glycolysis | Breast Neoplasms - mortality | Protein Processing, Post-Translational | Complications and side effects | Care and treatment | Patient outcomes | Physiological aspects | Development and progression | Research | Carcinogenesis | Risk factors | Integrins | Medical research | Dehydrogenases | Metabolites | Cloning | Breast cancer | Glucose | Metabolism | Gene expression
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 1/2014, Volume 111, Issue 1, pp. 279 - 284
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2012, Volume 337, Issue 6090, pp. 96 - 100
Pyruvate constitutes a critical branch point in cellular carbon metabolism. We have identified two proteins, Mpc1 and Mpc2, as essential for mitochondrial pyruvate transport in yeast, , and humans... 
Yeasts | Mitochondria | Diet | Plasmids | Drosophila | REPORTS | Amino acids | Oxidation | Respiration | Sugars | Medical schools | RAT-LIVER | TRANSPORT | COMPLEX | MECHANISM | IDENTIFICATION | MULTIDISCIPLINARY SCIENCES | Metabolomics | Humans | Molecular Sequence Data | Mitochondrial Proteins - genetics | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Anion Transport Proteins - chemistry | Mitochondrial Membrane Transport Proteins - genetics | Drosophila melanogaster - metabolism | Saccharomyces cerevisiae - metabolism | Amino Acids - metabolism | Biological Transport | Mitochondrial Proteins - metabolism | Pyruvic Acid - metabolism | Amino Acid Sequence | Mitochondrial Membrane Transport Proteins - chemistry | Mitochondrial Membrane Transport Proteins - metabolism | Oxidation-Reduction | Carbohydrate Metabolism | Mitochondria - metabolism | Drosophila Proteins - chemistry | Saccharomyces cerevisiae Proteins - genetics | Anion Transport Proteins - metabolism | Citric Acid Cycle | Mitochondrial Membranes - metabolism | Point Mutation | Animals | Drosophila melanogaster - chemistry | Mitochondrial Proteins - chemistry | Saccharomyces cerevisiae Proteins - metabolism | Drosophila Proteins - genetics | Anion Transport Proteins - genetics | Saccharomyces cerevisiae Proteins - chemistry | Cell metabolism | Pyruvates | Chemical properties | Research | Molecular biology | Proteins | Yeast | Metabolism | Carriers | Human | Bacteria | Transport | Transporter
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2004, Volume 279, Issue 19, pp. 20314 - 20326
...), a step which is essential for glucose metabolism in liver as well as for the induction of glycolytic and lipogenic genes... 
FATTY-ACID-SYNTHASE | GLUCOSE-HOMEOSTASIS | CARBOHYDRATE RESPONSE ELEMENT | RAT HEPATOCYTES | STEROL REGULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ELEMENT-BINDING PROTEIN-1C | PYRUVATE-KINASE GENE | TRANSCRIPTION FACTOR | CARNITINE-PALMITOYLTRANSFERASE-I | TRANSGENIC MICE | Glucokinase - physiology | Liver - enzymology | Fatty Acid Synthases - metabolism | Immunoblotting | Hepatocytes - metabolism | RNA, Messenger - metabolism | DNA-Binding Proteins - metabolism | Cell Nucleus - metabolism | Glycogen - metabolism | Time Factors | CCAAT-Enhancer-Binding Proteins - physiology | Adenoviridae - genetics | Transcription, Genetic | Pentosephosphates - metabolism | RNA - metabolism | CCAAT-Enhancer-Binding Proteins - metabolism | DNA-Binding Proteins - physiology | Pyruvate Kinase - metabolism | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Carbohydrate Metabolism | Cells, Cultured | Gene Expression Regulation | Lipid Metabolism | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Nuclear Proteins | Transcription Factors - metabolism | Blotting, Northern | Animals | Proteins - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors | Glucose - metabolism | Mice | Kinetics | Sterol Regulatory Element Binding Protein 1 | Glucose-6-Phosphate - metabolism | Acetyl-CoA Carboxylase - metabolism | Microscopy, Fluorescence | RNA, Small Interfering - metabolism
Journal Article
Nature (London), ISSN 1476-4687, 2014, Volume 510, Issue 7504, pp. 298 - 302
Journal Article
Free radical biology & medicine, ISSN 0891-5849, 2019, Volume 131, pp. 144 - 153
.... Allicin induces apoptosis or necrosis in a dose-dependent manner but biocompatible doses influence cellular metabolism and signalling cascades... 
T-cells | Cysteine | Allicin | IL-2 | S-thioallylation | Zinc | Protein modification | Actin | Glycolysis | Fibroblasts | Cytoskeleton | Interleukin IL-1 | Jurkat | Enolase | Warburg effect | APOPTOSIS | PHOSPHORYLATION | INHIBITION | ANTIBACTERIAL PRINCIPLE | ENDOCRINOLOGY & METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEMBRANES | FILAMENTS | ADF/COFILIN | CELL | Proteome - genetics | Actin Depolymerizing Factors - genetics | Membrane Glycoproteins - metabolism | Zinc - metabolism | Humans | Actins - metabolism | Sulfinic Acids - pharmacology | Garlic - chemistry | Tubulin - genetics | Actins - genetics | Actin Depolymerizing Factors - metabolism | Sulfhydryl Compounds - metabolism | Tubulin - metabolism | Sulfinic Acids - isolation & purification | Eukaryotic Initiation Factor-2 - metabolism | HSP90 Heat-Shock Proteins - genetics | Microfilament Proteins - metabolism | Filamins - genetics | Fructose-Bisphosphate Aldolase - metabolism | Microfilament Proteins - genetics | Fibroblasts - metabolism | Cell Line | Pyruvate Kinase - metabolism | Jurkat Cells | Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) - genetics | Membrane Glycoproteins - genetics | HSP110 Heat-Shock Proteins - genetics | Filamins - metabolism | Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) - metabolism | Animals | Eukaryotic Initiation Factor-2 - genetics | Fibroblasts - drug effects | HSP90 Heat-Shock Proteins - metabolism | Fibroblasts - cytology | Mice | Protein Processing, Post-Translational | Fructose-Bisphosphate Aldolase - genetics | HSP110 Heat-Shock Proteins - metabolism | Proteome - metabolism | Pyruvate Kinase - genetics
Journal Article
Cell metabolism, ISSN 1550-4131, 2012, Volume 15, Issue 6, pp. 827 - 837
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2014, Volume 111, Issue 43, pp. 15579 - 15584
Journal Article