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Journal of Biological Chemistry, ISSN 0021-9258, 2014, Volume 289, Issue 36, pp. 25382 - 25392
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 9814 - 14
Journal Article
Plant Physiology, ISSN 0032-0889, 2/2013, Volume 161, Issue 2, pp. 628 - 643
The aim of this work was to investigate the effect of decreased cytosolic phosphoenolpyruvate carboxykinase (PEPCK) and plastidic NADP-dependent malic enzyme... 
Ripening | Phosphates | Enzymes | Pericarp | Starches | Plants | BIOCHEMISTRY AND METABOLISM | Metabolism | Transgenic plants | Organic acids | Plant cells | PHOSPHOENOLPYRUVATE CARBOXYKINASE | GAS-CHROMATOGRAPHY | ADENOSINE 5'-DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE | CATALYTIC-PROPERTIES | POSTTRANSLATIONAL REDOX-ACTIVATION | GROWING POTATO-TUBERS | NADP-MALIC ENZYME | ADP-GLUCOSE PYROPHOSPHORYLASE | CARBON METABOLISM | CARBOHYDRATE-METABOLISM | PLANT SCIENCES | Malate Dehydrogenase - metabolism | Lycopersicon esculentum - metabolism | Carbohydrate Metabolism | Starch - metabolism | Fruit - physiology | Lycopersicon esculentum - physiology | Reverse Transcriptase Polymerase Chain Reaction | Metabolome - genetics | Malate Dehydrogenase - genetics | Gene Expression Regulation, Enzymologic | Phosphoenolpyruvate Carboxykinase (ATP) - genetics | RNA Interference | Phosphoenolpyruvate Carboxykinase (ATP) - metabolism | Plants, Genetically Modified | Gene Expression Regulation, Plant | Malates - metabolism | Carboxylic Acids - metabolism | Pyruvic Acid - metabolism | Cytosol - metabolism | Lycopersicon esculentum - genetics | Plastids - metabolism | Fruit - metabolism | Fruit - genetics | Pyruvates | Starch | Bioaccumulation | Crops | NADP (Coenzyme) | Physiological aspects | Malic acid | Genetic aspects | Tomatoes | Properties | Index Medicus
Journal Article
Science, ISSN 0036-8075, 7/2012, Volume 337, Issue 6090, pp. 93 - 96
The transport of pyruvate, the end product of glycolysis, into mitochondria is an essential process that provides the organelle with a major oxidative fuel.... 
Essential amino acids | Yeasts | Lactates | Cell growth | Mitochondria | Dehydrogenases | REPORTS | Mitochondrial membranes | Amino acids | Keto acids | Implementation maturity model | CATABOLISM | TRANSPORT | SPECIFICITY | LIPOIC ACID | MEMBRANE | MULTIDISCIPLINARY SCIENCES | SACCHAROMYCES-CEREVISIAE | LACTOCOCCUS-LACTIS | DEHYDROGENASE | Proprotein Convertase 2 | Proprotein Convertase 1 - genetics | Saccharomyces cerevisiae - genetics | Thioctic Acid - biosynthesis | Molecular Sequence Data | Lactococcus lactis - metabolism | Anion Transport Proteins - chemistry | Mitochondrial Membrane Transport Proteins - genetics | Thioctic Acid - metabolism | Saccharomyces cerevisiae - metabolism | Biological Transport | Culture Media | Pyruvic Acid - metabolism | Proprotein Convertase 1 - chemistry | Lactococcus lactis - genetics | Recombinant Proteins - metabolism | Amino Acid Sequence | Leucine - metabolism | Mitochondrial Membrane Transport Proteins - chemistry | Mitochondrial Membrane Transport Proteins - metabolism | Proprotein Convertase 1 - metabolism | Biosynthetic Pathways | Mitochondria - metabolism | Saccharomyces cerevisiae Proteins - genetics | Anion Transport Proteins - metabolism | Mitochondrial Membranes - metabolism | Animals | Valine - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Mice | Anion Transport Proteins - genetics | Saccharomyces cerevisiae - growth & development | Saccharomyces cerevisiae Proteins - chemistry | Plant mitochondria | Genetic aspects | Research | Plant molecular biology | Proteins | Glycoproteins | Yeast | Mutagenesis | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, pp. e23183 - e23183
Elevated concentrations of serum non-esterified fatty acids (NEFA), associated with maternal disorders such as obesity and type II diabetes, alter the ovarian... 
IN-VITRO | OBESITY | INFERTILE WOMEN | METABOLISM | GLUCOSE-TRANSPORTER | MULTIDISCIPLINARY SCIENCES | PREIMPLANTATION DEVELOPMENT | STEARIC-ACID | BODY-MASS INDEX | PALMITIC ACID | INDUCE APOPTOSIS | Palmitic Acid - pharmacology | Apoptosis - drug effects | Cell Count | Zygote - metabolism | Blastocyst - physiology | Male | Fatty Acids, Nonesterified - pharmacology | Oxygen - metabolism | Receptor, IGF Type 2 - genetics | Amino Acids - metabolism | Oocytes - cytology | Oleic Acid - pharmacology | Palmitic Acid - blood | Cattle | Oleic Acid - blood | Pyruvic Acid - metabolism | Fatty Acids, Nonesterified - blood | Female | Zygote - cytology | Oocytes - metabolism | Blastocyst - metabolism | Gene Expression Regulation, Developmental - drug effects | Blastocyst - cytology | Reverse Transcriptase Polymerase Chain Reaction | DNA (Cytosine-5-)-Methyltransferases - genetics | Animals | Lactates - metabolism | Oocytes - physiology | Glucose Transporter Type 1 - genetics | Stearic Acids - blood | Glucose - metabolism | Zygote - physiology | Stearic Acids - pharmacology | Lactates | Obesity | Embryonic development | Embryo | Methyltransferases | RNA | Genes | Amino acids | Fatty acids | Apoptosis | Laboratories | Oxidative metabolism | Pyruvic acid | mRNA | Biochemistry | Oocytes | Insulin-like growth factor II receptors | Fertility | Quality | DNA methylation | Physiology | Carbohydrates | Maturation | Diabetes mellitus | Oxygen consumption | Blastocysts | Gene expression | Metabolism | Embryos | Esterification | Zygotes | Cell number | Insulin resistance | Hypoxia | Reproductive technologies | Diabetes | Lactic acid | Miscarriage | Viability | Metabolic disorders | Pharmaceuticals | Index Medicus
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 57, Issue 4, pp. 774 - 779
Journal Article
Journal of Animal Science, ISSN 0021-8812, 04/2016, Volume 94, pp. 23 - 23
  An abstract of study that determined the effects of a copresence of saturated and unsaturated on cellular partitioning of (1-^sup 14^C) C16:0 metabolism to... 
Enzymes | Oxidation | Metabolism | Cattle | Fatty acids | Physiological effects | Correlation | Carbon dioxide | Pyruvic acid | Exposure | Mental depression | Gene expression | Pyruvate carboxylase | Partitioning | Physiological factors | Lactic acid | Pretreatment | Chemical synthesis | Carbon 14 | Deoxyribonucleic acid--DNA | Gluconeogenesis
Journal Article
Molecular Medicine Reports, ISSN 1791-2997, 12/2015, Volume 12, Issue 6, pp. 7899 - 7906
Heart failure is a disease predominantly caused by an energy metabolic disorder in cardiomyocytes. The present study investigated the inhibitory effects of... 
uncoupling protein 2 | heart failure | fenofibrate | isoproterenol | peroxisome proliferator-activated receptor α | Fenofibrate | Heart failure | Peroxisome proliferator-activated receptor | Uncoupling protein 2 | Isoproterenol | MEDICINE, RESEARCH & EXPERIMENTAL | PPAR-ALPHA | UNCOUPLING PROTEINS | TRANSCRIPTION | CARDIOMYOCYTES | BETA/DELTA | ONCOLOGY | FAILING HEART | CARDIOVASCULAR-DISEASE | peroxisome proliferator-activated receptor | ENERGY-METABOLISM | RECEPTORS | BURDEN | Reactive Oxygen Species - metabolism | Cells, Cultured | Rats | Male | Heart Failure - metabolism | Hypolipidemic Agents - pharmacology | Fenofibrate - therapeutic use | Rats, Sprague-Dawley | Heart Failure - drug therapy | Necrosis | Fenofibrate - pharmacology | Animals | Myocytes, Cardiac - drug effects | Ion Channels - metabolism | Mitochondrial Proteins - metabolism | Myocytes, Cardiac - metabolism | Hypolipidemic Agents - therapeutic use | Uncoupling Protein 2 | PPAR alpha - metabolism | Fatty Acids - metabolism | Energy Metabolism - drug effects | Heart Failure - chemically induced | Complications and side effects | Research | Drug therapy | Health aspects | Neonates | Mitochondrial uncoupling protein 2 | Phosphorylation | Pyruvic acid | Lipids | Cardiovascular disease | Mitochondria | Rodents | Standard deviation | Oxidation | Pharmaceutical industry | Heart diseases | Brain natriuretic peptide | Mortality | Cardiomyocytes | Metabolism | Fatty acids | Coronary artery disease | Serum levels | Ligands | Lactic acid | Peroxisome proliferator-activated receptors | Laboratory animals | Metabolic disorders | Structure-function relationships
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, pp. e79977 - e79977
We previously demonstrated that mitochondrial bioenergetic deficits in the female brain accompanied reproductive senescence and was accompanied by a shift from... 
MECHANISM | ASTROCYTE | MULTIDISCIPLINARY SCIENCES | LACTATE | DISEASE | HIPPOCAMPAL | ESTRADIOL | COGNITIVE IMPAIRMENT | ENERGY-METABOLISM | EXPRESSION | OLIGODENDROCYTES | Adaptation, Physiological | Ketone Oxidoreductases - metabolism | Neurons - pathology | Humans | Ketone Bodies - metabolism | Astrocytes - pathology | Glucose Transporter Type 1 - metabolism | Alzheimer Disease - pathology | Biological Transport, Active | Monocarboxylic Acid Transporters - metabolism | Aging - genetics | Female | Neurons - metabolism | Hexokinase - genetics | Disease Models, Animal | Gene Expression | Lactic Acid - metabolism | Mice, Transgenic | Hippocampus - pathology | Mitochondria - metabolism | Ketone Oxidoreductases - genetics | Aging - pathology | Blood-Brain Barrier - metabolism | Hippocampus - metabolism | Animals | Energy Metabolism | Glucose Transporter Type 1 - genetics | Alzheimer Disease - metabolism | Glucose - metabolism | Mice | Monocarboxylic Acid Transporters - genetics | Alzheimer Disease - genetics | Hexokinase - metabolism | Aging - metabolism | Astrocytes - metabolism | Lactates | Glucose metabolism | Enzymes | Brain | Neurons | Glucose | Alzheimer's disease | Dextrose | Neurosciences | Senescence | Adaptive systems | Dehydrogenases | Pyruvic acid | Ketone bodies | Fuels | Mitochondria | Bioenergetics | Blood-brain barrier | Rodents | Aging | Pharmaceutical sciences | Age | Glucose transporter | Phenotypes | Medical imaging | Neurodegenerative diseases | Ketones | Astrocytes | Pharmacology | Metabolism | Glucose transport | Fatty acids | Hexokinase | Utilization | Pharmacy | Glycolysis | Lactic acid | Laboratory animals | Transport | Alzheimers disease | Axonal transport | Transporter | Hippocampus | Animal cognition | Index Medicus
Journal Article
Science, ISSN 0036-8075, 7/2012, Volume 337, Issue 6090, pp. 96 - 100
Pyruvate constitutes a critical branch point in cellular carbon metabolism. We have identified two proteins, Mpc1 and Mpc2, as essential for mitochondrial... 
Yeasts | Mitochondria | Diet | Plasmids | Drosophila | REPORTS | Amino acids | Oxidation | Respiration | Sugars | Medical schools | RAT-LIVER | TRANSPORT | COMPLEX | MECHANISM | IDENTIFICATION | MULTIDISCIPLINARY SCIENCES | Metabolomics | Humans | Molecular Sequence Data | Mitochondrial Proteins - genetics | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Anion Transport Proteins - chemistry | Mitochondrial Membrane Transport Proteins - genetics | Drosophila melanogaster - metabolism | Saccharomyces cerevisiae - metabolism | Amino Acids - metabolism | Biological Transport | Mitochondrial Proteins - metabolism | Pyruvic Acid - metabolism | Amino Acid Sequence | Mitochondrial Membrane Transport Proteins - chemistry | Mitochondrial Membrane Transport Proteins - metabolism | Oxidation-Reduction | Carbohydrate Metabolism | Mitochondria - metabolism | Drosophila Proteins - chemistry | Saccharomyces cerevisiae Proteins - genetics | Anion Transport Proteins - metabolism | Citric Acid Cycle | Mitochondrial Membranes - metabolism | Point Mutation | Animals | Drosophila melanogaster - chemistry | Mitochondrial Proteins - chemistry | Saccharomyces cerevisiae Proteins - metabolism | Drosophila Proteins - genetics | Anion Transport Proteins - genetics | Saccharomyces cerevisiae Proteins - chemistry | Cell metabolism | Pyruvates | Chemical properties | Research | Molecular biology | Proteins | Yeast | Metabolism | Index Medicus | Carriers | Human | Bacteria | Transport | Transporter
Journal Article