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1. Full Text Quinolinic acid, the inescapable neurotoxin
by Guillemin, Gilles J
The FEBS journal, ISSN 1742-464X, 04/2012, Volume 279, Issue 8, pp. 1356 - 1365
neurodegeneration | quinolinic acid | kynurenine pathway | neuroinflammation | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Neurotoxicity Syndromes - etiology | Quinolinic Acid - adverse effects | Animals | Humans | Neurotoxins - adverse effects | Methyl aspartate | Nervous system diseases | Brain | Cytotoxicity | Neurotoxicity | Biochemistry | Toxins | Index Medicus
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2. Full Text Connecting inflammation with glutamate agonism in suicidality
by Erhardt, Sophie and Lim, Chai K and Linderholm, Klas R and Janelidze, Shorena and Lindqvist, Daniel and Samuelsson, Martin and Lundberg, Kristina and Postolache, Teodor T and Träskman-Bendz, Lil and Guillemin, Gilles J and Brundin, Lena
Neuropsychopharmacology (New York, N.Y.), ISSN 0893-133X, 04/2013, Volume 38, Issue 5, pp. 743 - 752
cytokine | quinolinic acid | depression | glutamate | suicide | Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Psychopathology. Psychiatry | Mood disorders | Biological and medical sciences | Depression | Medical sciences | Suicide | Encephalitis - psychology | Excitatory Amino Acid Agonists - cerebrospinal fluid | Kynurenine - cerebrospinal fluid | Quinolinic Acid - cerebrospinal fluid | Excitatory Amino Acid Agonists - therapeutic use | Follow-Up Studies | Somatosensory Disorders - complications | Spinal Puncture | Humans | Middle Aged | Male | Mental Disorders - complications | Kynurenic Acid - cerebrospinal fluid | Mental Disorders - psychology | Young Adult | Psychiatric Status Rating Scales | Tritium - cerebrospinal fluid | Encephalitis - cerebrospinal fluid | Suicide - psychology | Adult | Female | Aged | Retrospective Studies | Interleukin-6 - metabolism | Index Medicus | Brain | Glutamic acid | Glutamic acid receptors (ionotropic) | Mass spectroscopy | N-Methyl-D-aspartic acid receptors | Glutamic acid receptors | Inflammation | Cerebrospinal fluid | High-performance liquid chromatography | Interleukin 6 | Gas chromatography | Ketamine | Glutamatergic transmission | Kynurenic acid | Quinolinic acid | Neurotransmission | Original | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Farmakologi och toxikologi | Pharmacology and Toxicology
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3. Full Text Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder
by Savitz, Jonathan and Drevets, Wayne C and Wurfel, Brent E and Ford, Bart N and Bellgowan, Patrick S.F and Victor, Teresa A and Bodurka, Jerzy and Teague, T. Kent and Dantzer, Robert
Brain, behavior, and immunity, ISSN 0889-1591, 2015, Volume 46, pp. 55 - 59
Psychiatry | Allergy and Immunology | Kynurenine | Remission | Anhedonia | Inflammation | Kynurenic acid | Quinolinic acid | Major depressive disorder | Neurosciences | Immunology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Depressive Disorder, Major - blood | Depressive Disorder, Major - metabolism | Humans | Middle Aged | Quinolinic Acid - blood | Male | Kynurenic Acid - metabolism | Young Adult | Tandem Mass Spectrometry | Adolescent | Chromatography, Liquid | Adult | Female | Depression, Mental | Organic acids | Index Medicus
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4. Full Text Development of a CZE‐ESI‐MS assay with a sulfonated capillary for profiling picolinic acid and quinolinic acid formation in multienzyme system
by Wang, Xiaochun and Davis, Ian and Liu, Aimin and Shamsi, Shahab A
Electrophoresis, ISSN 0173-0835, 06/2013, Volume 34, Issue 12, pp. 1828 - 1835
CZE‐MS / Enzyme | Picolinic acid | Quinolinic acid | 3‐Hydroxyanthranilic acid | 3-Hydroxyanthranilic acid | CZE-MS/Enzyme | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Reproducibility of Results | 3-Hydroxyanthranilic Acid - analysis | Multienzyme Complexes - metabolism | 3-Hydroxyanthranilic Acid - metabolism | Electrophoresis, Capillary - instrumentation | Pressure | Picolinic Acids - metabolism | Multienzyme Complexes - chemistry | Picolinic Acids - analysis | Spectrometry, Mass, Electrospray Ionization - methods | Quinolinic Acid - analysis | Quinolinic Acid - metabolism | Carboxy-Lyases - metabolism | Buffers | Electrophoresis, Capillary - methods | 3-Hydroxyanthranilate 3,4-Dioxygenase - metabolism | Hydrogen-Ion Concentration | Tryptophan | Enzymes | Metabolites | Analysis | Index Medicus | Consumption | Capillarity | Decay | Electrophoresis | Assaying
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5. Full Text Quinolinic acid: neurotoxicity
by Guillemin, Gilles J
The FEBS journal, ISSN 1742-464X, 04/2012, Volume 279, Issue 8, pp. 1355 - 1355
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Neurotoxicity Syndromes - etiology | Quinolinic Acid - adverse effects | Animals | Humans | Index Medicus
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6. Full Text Comparison of the Toxic Effects of Quinolinic Acid and 3-Nitropropionic Acid in C. elegans: Involvement of the SKN-1 Pathway
by Kotlar, Ilan and Kotlar, Ilan and Colonnello, Aline and Colonnello, Aline and Aguilera-González, María Fernanda and Aguilera-González, María Fernanda and Avila, Daiana Silva and Avila, Daiana Silva and de Lima, María Eduarda and de Lima, María Eduarda and García-Contreras, Rodolfo and García-Contreras, Rodolfo and Ortíz-Plata, Alma and Ortíz-Plata, Alma and Soares, Félix Alexandre Antunes and Soares, Félix Alexandre Antunes and Aschner, Michael and Aschner, Michael and Santamaría, Abel and Santamaría, Abel
Neurotoxicity research, ISSN 1029-8428, 2/2018, Volume 33, Issue 2, pp. 259 - 267
Neurochemistry | Neurosciences | VC1772 | Neurobiology | SKN-1 | Cell Biology | Neurology | Biomedicine | Excitotoxicity | NMDA | VP596 | Huntington’s disease | Pharmacology/Toxicology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Nitro Compounds - toxicity | DNA-Binding Proteins - drug effects | Caenorhabditis elegans Proteins - metabolism | Mitochondria - drug effects | Propionates - toxicity | Transcription Factors - drug effects | Transcription Factors - metabolism | Caenorhabditis elegans | Antihypertensive Agents - toxicity | Animals | Caenorhabditis elegans Proteins - drug effects | Corpus Striatum - drug effects | Neurotoxicity Syndromes - metabolism | Quinolinic Acid - toxicity | Oxidative Stress - drug effects | Disease Models, Animal | Tryptophan | Comparative analysis | Glutathione transferase | Nematoda | Index Medicus
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7. Ischemic Stroke and Kynurenines: Medicinal Chemistry Aspects
by Hertelendy, Péter and Toldi, József and Fülöp, Ferenc and Vécsei, László
Current medicinal chemistry, ISSN 0929-8673, 2018, Volume 25, Issue 42, p. 5945
Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Excitatory Amino Acid Antagonists - therapeutic use | Quinolinic Acids - metabolism | Kynurenine - therapeutic use | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Kynurenine - chemistry | Kynurenic Acid - therapeutic use | Stroke - drug therapy | Kynurenic Acid - metabolism | Kynurenine - analogs & derivatives | Tryptophan - metabolism | Quinolinic Acids - chemistry | Stroke - pathology | Kynurenic Acid - analogs & derivatives | Quinolinic Acids - therapeutic use | Excitatory Amino Acid Antagonists - chemistry | Kynurenine - metabolism | Developed countries | Stroke | Calcium | Glutamic acid receptors (ionotropic) | Tryptophan | N-Methyl-D-aspartic acid receptors | Inflammation | Drug development | Organic chemistry | Ischemia | Metabolites | Cell death | Cascades | Excitotoxicity | Catabolism | Kynurenic acid | Apoptosis
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8. Full Text Kynurenine, quinolinic acid—The new factors linked to carotid atherosclerosis in patients with end-stage renal disease
by Pawlak, Krystyna and Brzosko, Szymon and Mysliwiec, Michal and Pawlak, Dariusz
Atherosclerosis, ISSN 0021-9150, 2008, Volume 204, Issue 2, pp. 561 - 566
Cardiovascular | End-stage renal disease | Oxidative stress | Carotid atherosclerosis | Kynurenine | Inflammation | Kynurenic acid | Quinolinic acid | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Biological and medical sciences | Medical sciences | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Atherosclerosis (general aspects, experimental research) | Blood and lymphatic vessels | Kynurenic Acid - blood | Age Factors | Oxidative Stress | Humans | Middle Aged | Quinolinic Acid - blood | Superoxide Dismutase - blood | Male | Inflammation - blood | Kynurenine - blood | Carotid Artery Diseases - diagnostic imaging | Malondialdehyde - blood | Ultrasonography | Adult | Female | Peritoneal Dialysis, Continuous Ambulatory | C-Reactive Protein - analysis | Carotid Artery Diseases - etiology | Cross-Sectional Studies | Risk Assessment | Risk Factors | Inflammation Mediators - blood | Logistic Models | Biomarkers - blood | Inflammation - etiology | Diabetes Complications - etiology | Disease Progression | Kidney Failure, Chronic - therapy | Peroxides - blood | Kidney Failure, Chronic - blood | Uremia - blood | Carotid Artery Diseases - blood | Kidney Failure, Chronic - complications | Uremia - etiology | Renal Dialysis | Medical colleges | Zinc compounds | Care and treatment | C-reactive protein | Analysis | Atherosclerosis | Superoxide dismutase | Development and progression | Superoxide | Kidney diseases | Diabetes | Organic acids | Index Medicus
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9. Full Text Kynurenic Acid Restores Nrf2 Levels and Prevents Quinolinic Acid-Induced Toxicity in Rat Striatal Slices
by Ferreira, Fernanda Silva and Biasibetti-Brendler, Helena and Pierozan, Paula and Schmitz, Felipe and Bertó, Carolina Gessinger and Prezzi, Caroline Acauan and Manfredini, Vanusa and Wyse, Angela T. S
Molecular neurobiology, ISSN 0893-7648, 11/2018, Volume 55, Issue 11, pp. 8538 - 8549
Neurology | Neurosciences | Biomedicine | Nrf2 | Mitochondrial function | Neurobiology | Kynurenic acid | Quinolinic acid | Oxidative status | Cell Biology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Oxidation-Reduction | Rats, Wistar | Antioxidants - metabolism | Fluoresceins - metabolism | Receptors, N-Methyl-D-Aspartate - metabolism | Nitrites - metabolism | Male | Mitochondria - metabolism | Mitochondria - drug effects | Sodium-Potassium-Exchanging ATPase - metabolism | Sulfhydryl Compounds - metabolism | Animals | Cell Nucleus - metabolism | Neuroprotective Agents - pharmacology | NF-E2-Related Factor 2 - metabolism | Quinolinic Acid - toxicity | Kynurenic Acid - pharmacology | Cell Nucleus - drug effects | Corpus Striatum - pathology | Nitric Oxide Synthase Type II - metabolism | Prevention | Antioxidants | Evaluation | Medical research | Nervous system diseases | Huntington's chorea | Metabolites | Tryptophan | Medicine, Experimental | Alzheimer's disease | Adenosine triphosphatase | Reactive oxygen species | Toxicity | DNA damage | Brain slice preparation | Central nervous system | Lipid peroxidation | Mitochondria | Neurodegeneration | Rodents | Neostriatum | Membrane potential | Deoxyribonucleic acid--DNA | Peroxidation | Enzymes | Incubation | Rats | Na+/K+-exchanging ATPase | Nitric-oxide synthase | Acids | Electron transport | Index Medicus
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