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Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 11, p. e112945
The kynurenine pathway (KP) is the principal route of L-tryptophan (TRP) catabolism leading to the production of kynurenine (KYN), the neuroprotectants,... 
QUINOLINIC ACID | INHIBITION | METABOLISM | AMINOTRANSFERASE | MULTIDISCIPLINARY SCIENCES | INDOLEAMINE 2,3-DIOXYGENASE | T-CELL | TUMORAL IMMUNE RESISTANCE | TRYPTOPHAN DEGRADATION | IDO EXPRESSION | BRAIN | Immunohistochemistry | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Kynurenic Acid - blood | Gene Expression - drug effects | Humans | Kynurenine - biosynthesis | Brain Neoplasms - physiopathology | Picolinic Acids - blood | Quinolinic Acid - blood | Chromatography, High Pressure Liquid | Glial Fibrillary Acidic Protein - metabolism | Kynurenic Acid - metabolism | Carboxy-Lyases - genetics | Tryptophan - metabolism | Brain Neoplasms - metabolism | Picolinic Acids - metabolism | Antigens, CD - metabolism | Glioma - metabolism | Glioma - genetics | Kynurenine - blood | Tryptophan - blood | Carboxy-Lyases - metabolism | Tumor Cells, Cultured | Astrocytes - drug effects | Disaccharides | Cells, Cultured | Brain Neoplasms - genetics | Biosynthetic Pathways | Reverse Transcriptase Polymerase Chain Reaction | Glucuronates | Tryptophan Oxygenase - metabolism | Tryptophan Oxygenase - genetics | Antigens, Differentiation, Myelomonocytic - metabolism | Quinolinic Acid - metabolism | CD11b Antigen - metabolism | Glioma - physiopathology | Interferon-gamma - pharmacology | Astrocytes - metabolism | Tryptophan | Niacinamide | Methyl aspartate | Enzymes | Metabolites | Gliomas | NADPH | Neuroprotection | Brain | Brain tumors | Brain cancer | Glioblastoma | Tryptophan 2,3-dioxygenase | Immunity | DNA repair | Picolinic acid | Rodents | Glioma cells | L-Tryptophan | Kynurenic acid | Quinolinic acid | Deoxyribonucleic acid--DNA | Pyridines | Medical research | Hydroxylase | Adenine | Kynurenine-oxoglutarate transaminase | NAD | Acids | γ-Interferon | Nicotinamide adenine dinucleotide | Catabolism | Nicotinamide | Interferon | Tumors | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2010, Volume 5, Issue 1, p. e8550
Ciliary neurotrophic factor (CNTF) is a potent neuroprotective cytokine in different animal models of glutamate-induced excitotoxicity, although its action... 
FACTOR-RECEPTOR | QUINOLINIC ACID | CNTF | IN-VIVO | BIOLOGY | CENTRAL-NERVOUS-SYSTEM | REACTIVE GLIOSIS | GENE-TRANSFER | HUNTINGTONS-DISEASE | RAT MODEL | RAFT MICRODOMAINS | Ciliary Neurotrophic Factor - physiology | Rats | Evoked Potentials - physiology | Corpus Striatum - cytology | Corpus Striatum - metabolism | Evoked Potentials - drug effects | Quinolinic Acid - pharmacology | Amino Acid Transport System X-AG - antagonists & inhibitors | Animals | Corpus Striatum - drug effects | Glutamic Acid - metabolism | Neurons - metabolism | In Vitro Techniques | Neurons - drug effects | Aspartic Acid - pharmacology | Nervous system diseases | Cytokines | Neurons | Amino acids | Ciliary neurotrophic factor | Comparative analysis | Glutamate | Huntingtons disease | Neuroprotection | Animal models | Glutamic acid receptors | Recovery | Neuronal-glial interactions | Overflow | Neurotoxicity | Neurodegeneration | Rodents | Neostriatum | Trends | Quinolinic acid | Excitation | Localization | Enzymes | Dopamine | Neurodegenerative diseases | Medical treatment | Cortex | Data processing | Spiny neurons | Neurological diseases | Brain research | Excitotoxicity | Cocaine | Glutamatergic transmission | Alzheimers disease | Neurons and Cognition | Evoked Potentials | Neurobiology | Amino Acid Transport System X-AG | Aspartic Acid | Quinolinic Acid | Glutamic Acid | Life Sciences | Ciliary Neurotrophic Factor | Corpus Striatum
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 04/2013, Volume 38, Issue 5, pp. 743 - 752
The NMDA-receptor antagonist ketamine has proven efficient in reducing symptoms of suicidality, although the mechanisms explaining this effect have not been... 
cytokine | quinolinic acid | depression | glutamate | suicide | PSYCHIATRY | RESISTANT DEPRESSION | ADD-ON TRIAL | D-ASPARTATE ANTAGONIST | NEUROSCIENCES | HIPPOCAMPAL VOLUME | EMERGENCY-DEPARTMENT | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | KYNURENIC ACID | MAJOR DEPRESSIVE DISORDER | Encephalitis - psychology | Excitatory Amino Acid Agonists - cerebrospinal fluid | Kynurenine - cerebrospinal fluid | Quinolinic Acid - cerebrospinal fluid | Excitatory Amino Acid Agonists - therapeutic use | Follow-Up Studies | Somatosensory Disorders - complications | Spinal Puncture | Humans | Middle Aged | Male | Mental Disorders - complications | Kynurenic Acid - cerebrospinal fluid | Mental Disorders - psychology | Young Adult | Psychiatric Status Rating Scales | Tritium - cerebrospinal fluid | Encephalitis - cerebrospinal fluid | Suicide - psychology | Adult | Female | Aged | Retrospective Studies | Interleukin-6 - metabolism | Brain | Glutamic acid | Glutamic acid receptors (ionotropic) | Depression | Mass spectroscopy | N-Methyl-D-aspartic acid receptors | Glutamic acid receptors | Inflammation | Cerebrospinal fluid | High-performance liquid chromatography | Suicide | Interleukin 6 | Gas chromatography | Ketamine | Glutamatergic transmission | Kynurenic acid | Quinolinic acid | Neurotransmission | Original | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICIN | MEDICINE
Journal Article
1989, ISBN 9780849365928, 307
Book
Journal Article
FEBS Journal, ISSN 1742-464X, 04/2012, Volume 279, Issue 8, pp. 1355 - 1355
This minireview series reviews some of the most recent findings about quinolinic acid’s cellular toxicity and its implications in diseases such as HIV... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | Neurotoxicity Syndromes - etiology | Quinolinic Acid - adverse effects | Animals | Humans
Journal Article
Neurotoxicity Research, ISSN 1029-8428, 2/2018, Volume 33, Issue 2, pp. 259 - 267
Journal Article