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International Journal of Pharmaceutics, ISSN 0378-5173, 05/2017, Volume 523, Issue 1, pp. 300 - 309
Metastasis impedes the successful chemotherapy for breast cancer. In this study, an Akt inhibitor (quercetin, Qu) was co-delivered with a chemotherapeutic... 
Metastasis docetaxel | Breast cancer | Akt/MMP-9 pathway | Hyaluronic acid | Quercetin | MMP-9 EXPRESSION | TARGETED DRUG-DELIVERY | POLYMERIC MICELLES | CELLULAR UPTAKE | COLON-CANCER | TUMOR XENOGRAFTS | IN-VIVO | COMBINATION CHEMOTHERAPY | PHARMACOLOGY & PHARMACY | ANTICANCER DRUGS | PI3K/AKT SIGNALING PATHWAY | Alct/MMP-9 pathway | Polyethylenes - administration & dosage | Antioxidants - chemistry | Nanoparticles - chemistry | Apoptosis - drug effects | Matrix Metalloproteinase Inhibitors - administration & dosage | Matrix Metalloproteinase Inhibitors - pharmacokinetics | Antineoplastic Agents - administration & dosage | Breast Neoplasms | Polyethylenes - pharmacokinetics | Lactic Acid - pharmacokinetics | Matrix Metalloproteinase 9 - metabolism | Quercetin - pharmacokinetics | Imines - chemistry | Quercetin - administration & dosage | Female | Antineoplastic Agents - pharmacokinetics | Proto-Oncogene Proteins c-akt - metabolism | Lactic Acid - administration & dosage | Polyethylenes - chemistry | Wound Healing - drug effects | Imines - administration & dosage | Polyglycolic Acid - administration & dosage | Taxoids - chemistry | Cell Survival - drug effects | Hyaluronic Acid - administration & dosage | Lactic Acid - chemistry | Quercetin - chemistry | Hyaluronic Acid - chemistry | Matrix Metalloproteinase Inhibitors - chemistry | Antineoplastic Agents - chemistry | Hyaluronic Acid - pharmacokinetics | Imines - pharmacokinetics | Taxoids - pharmacokinetics | Cell Movement - drug effects | Taxoids - administration & dosage | Animals | Polyglycolic Acid - pharmacokinetics | Polyglycolic Acid - chemistry | Antioxidants - administration & dosage | Cell Line, Tumor | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Antioxidants - pharmacokinetics | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Nanoparticles | Chemotherapy | Cancer cells | Metastasis | Cancer | Index Medicus
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 38, pp. 22 - 35
Abstract Nanodiamond application in biotechnological and medical fields is nowadays in continuous progress. In fact, biocompatibility, reduced dimensions and... 
Advanced Basic Science | Dentistry | Antineoplastic properties | Nanodiamonds | Ciproten (5,7-dimethoxycoumarin) | Quercetin (3,3′,4′,5,6-pentahydroxyflavone) | Therapeutic approach | Natural bioactive compounds | Quercetin (3,3',4',5,6-pentahydroxyflavone) | MATERIALS SCIENCE, BIOMATERIALS | METASTASIS | INDUCED APOPTOSIS | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | CELL-CYCLE ARREST | ANTIOXIDANT PROPERTIES | BREAST-CANCER | Quercetin (3,3 ',4 ',5,6-pentahydroxyflavone) | QUERCETIN | BIOMEDICAL APPLICATIONS | DETONATION NANODIAMOND | DIAMOND NANOPARTICLES | Plant Extracts - chemistry | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Nanocomposites - chemistry | Apoptosis - drug effects | Nanocapsules - administration & dosage | Humans | Drug Carriers - administration & dosage | Coumarins - chemistry | Nanocapsules - chemistry | Nanocapsules - ultrastructure | Neoplasms, Experimental - pathology | Plant Extracts - administration & dosage | Surface Properties | Quercetin - administration & dosage | Nanocomposites - ultrastructure | Diffusion | Cell Survival - drug effects | Nanodiamonds - ultrastructure | Quercetin - chemistry | Nanodiamonds - administration & dosage | Nanodiamonds - chemistry | Coumarins - administration & dosage | Materials Testing | Treatment Outcome | Particle Size | Animals | Mice | HeLa Cells | Neoplasms, Experimental - drug therapy | Nanocomposites - administration & dosage | Antimitotic agents | Care and treatment | Antineoplastic agents | Health aspects | Plant metabolites | Cancer | Index Medicus | Cellular | Antiproliferatives | Metabolites | Biocompatibility | Plants (organisms) | Medical | Nanostructure | Conjugation
Journal Article
Journal Article
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 01/2016, Volume 81, pp. 1 - 9
Journal Article
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 10/2014, Volume 75, pp. 149 - 155
A new strategy was designed to evaluate the antioxidant effectiveness of five topically applied polyphenols following skin penetration profiles. The... 
Franz cells | Polyphenols | Percutaneous absorption | Free radicals | In vitro | Antioxidant activity | RESVERATROL | VIVO | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOTOPROTECTION | IN-VITRO | EPICATECHIN | DISEASE | ENDOCRINOLOGY & METABOLISM | SYSTEMS | SKIN | ULTRAVIOLET-RADIATION | CATECHIN | Free Radical Scavengers - pharmacology | Stilbenes - administration & dosage | Antioxidants - chemistry | Free Radical Scavengers - chemistry | Skin - metabolism | Rutin - pharmacology | Polyphenols - pharmacology | Catechin - administration & dosage | Stilbenes - chemistry | Administration, Cutaneous | Chromatography, High Pressure Liquid | Stilbenes - pharmacology | Biphenyl Compounds - antagonists & inhibitors | Chromans - pharmacology | Swine | Picrates - chemistry | Quercetin - administration & dosage | Biphenyl Compounds - chemistry | Catechin - pharmacology | Chromans - administration & dosage | Chromans - chemistry | Quercetin - chemistry | Free Radical Scavengers - administration & dosage | Skin Absorption | Antioxidants - pharmacology | Picrates - antagonists & inhibitors | Animals | Quercetin - pharmacology | Polyphenols - chemistry | Rutin - administration & dosage | Antioxidants - administration & dosage | Rutin - chemistry | Polyphenols - administration & dosage | Catechin - chemistry | Skin - drug effects | Antioxidants | Resveratrol | Index Medicus
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 09/2013, Volume 170, Issue 2, pp. 440 - 457
BACKGROUND AND PURPOSE Flavonols and terpene lactones are putatively responsible for the properties of Ginkgo biloba leaf extracts that relate to prevention... 
inkgo biloba | GBE50 | terpene lactones | systemic exposure | ing injection | flavonols | pharmacokinetics | cerebral exposure | markers | route of administration | Ginkgo biloba | ShuXueNing injection | PK markers | ALZHEIMERS-DISEASE | EGB 761(R) | CORONARY-ARTERY | BIOAVAILABILITY | ADHESION MOLECULE EXPRESSION | QUERCETIN | PLASMA | ENDOTHELIAL-CELLS | IN-VIVO | PHARMACOLOGY & PHARMACY | BRAIN | Plant Extracts - chemistry | Plant Leaves | Flavonols - pharmacokinetics | Biological Availability | Male | Flavonols - isolation & purification | Glycosides - administration & dosage | Brain - metabolism | Plant Extracts - administration & dosage | Tissue Distribution | Lactones - pharmacokinetics | Lactones - administration & dosage | Mass Spectrometry | Chromatography, Liquid | Flavonols - administration & dosage | Drugs, Chinese Herbal - administration & dosage | Terpenes - isolation & purification | Lactones - isolation & purification | Administration, Oral | Rats | Ginkgo biloba - chemistry | Rats, Sprague-Dawley | Drugs, Chinese Herbal - pharmacokinetics | Animals | Microdialysis | Terpenes - administration & dosage | Terpenes - pharmacokinetics | Plant Extracts - pharmacokinetics | Glycosides - pharmacokinetics | Liquid chromatography | Medicine, Herbal | Medicine, Botanic | Lactones | Rodents | Chromatography | Human exposure | Index Medicus | Research Papers
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2009, Volume 182, Issue 6, pp. 3556 - 3565
Existing therapies for rheumatoid arthritis and other autoimmune diseases are not Ag specific, which increases the likelihood of systemic toxicity. We show... 
RHEUMATOID-ARTHRITIS | CD8 EXPRESSION | CYCLIC CITRULLINATED PEPTIDE | DENDRITIC CELLS | MOUSE THYMUS | CURCUMIN | IN-VIVO | LYMPH-NODES | REGULATORY T-CELLS | IMMUNOLOGY | NF-KAPPA-B | Injections, Intravenous | Drug Carriers - therapeutic use | Ovalbumin - immunology | Serum Albumin, Bovine - administration & dosage |