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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 05/2018, Volume 26, Issue 9, pp. 2199 - 2220
The quinazolinone-containing 2,3-disubstituted piperidines febrifugine and isofebrifugine have been the subject of significant research efforts since their... 
Halofuginone | Anti-fibrotic | Dichroine A and B | 3-hydroxypiperidine | Isomerization | Febrifugine | Quinazolinone | Anti-angiogenic | Isofebrifugine | Anti-protozoal | SEMICYCLIC N,O-ACETALS | CHEMISTRY, MEDICINAL | LEWIS-ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | MACROPHYLLA VAR. OTAKSA | CHEMISTRY, ORGANIC | NUCLEOPHILIC-SUBSTITUTION REACTIONS | HYDRANGEA-CHINENSIS | TRANSFER-RNA SYNTHETASE | ANTIMALARIAL ACTIVITY | CONCISE ENANTIOSELECTIVE SYNTHESIS | PLASMODIUM MALARIA PARASITE | CATALYTIC ASYMMETRIC-SYNTHESIS | Quinazolines - chemical synthesis | Piperidines - chemistry | Stereoisomerism | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Plasmodium falciparum - drug effects | Piperidines - chemical synthesis | Cycloaddition Reaction | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Antimalarials - pharmacology | Quinazolinones - chemical synthesis | Animals | Cyclization | Piperidines - pharmacology | Antimalarials - chemistry | Quinazolinones - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Quinazolines - pharmacology | Quinazolines - chemistry | Antimalarials - chemical synthesis | Quinazolinones - pharmacology | Malaria | Chemical tests and reagents | RNA | Ammonium paratungstate | Aluminum compounds | Fluorides | Biological response modifiers | Transforming growth factors | Muscle proteins | Lipase | Cytokinins | Ammonium compounds | Pyridine | Dimethyl sulfoxide | Interferon | Chemical synthesis | Adenosine triphosphate
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2015, Volume 90, pp. 124 - 169
The presence of -heterocycles as an essential structural motif in a variety of biologically active substances has stimulated the development of new strategies... 
Bioactive heterocycles | Enzymes | Biological potential | Synthetic methods | Inhibitors | Cross-coupling reactions | CHEMISTRY, MEDICINAL | ONE-POT SYNTHESIS | CRYSTAL-STRUCTURE | EFFICIENT SYNTHESIS | CELL LINES | NATIONAL-CANCER-INSTITUTE | C-H BONDS | ACRIDONE ALKALOIDS | ANTIINFLAMMATORY AGENTS | BIOLOGICAL EVALUATION | PROTEIN-KINASE INHIBITORS | Phosphotransferases - metabolism | Quinazolines - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Glucuronidase - metabolism | Phosphotransferases - antagonists & inhibitors | Enzyme Inhibitors - chemical synthesis | Anticonvulsants - pharmacology | Anti-Bacterial Agents - chemistry | Enzyme Inhibitors - chemistry | Glucuronidase - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Molecular Structure | Quinazolines - chemistry | Angiogenesis Inhibitors - chemical synthesis | Quinazolinones - pharmacology | Anticonvulsants - chemical synthesis | Enzyme Inhibitors - pharmacology | Angiogenesis Inhibitors - pharmacology | Antineoplastic Agents - chemistry | Tetrahydrofolate Dehydrogenase - metabolism | Anti-Bacterial Agents - chemical synthesis | Quinazolinones - chemical synthesis | Anticonvulsants - chemistry | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Quinazolinones - chemistry | Quinazolines - pharmacology | Angiogenesis Inhibitors - chemistry
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 11/2016, Volume 138, Issue 44, pp. 14578 - 14581
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 11/2013, Volume 78, Issue 22, pp. 11342 - 11348
The first example of a copper-catalyzed cascade reaction of (2-aminophenyl)methanols with aldehydes using the combination of cerium nitrate hexahydrate and... 
SYSTEM | NITROARENES | DESIGN | 2-SUBSTITUTED QUINAZOLINES | BENZAMIDINES | BIOLOGICAL EVALUATION | CHEMISTRY, ORGANIC | AEROBIC OXIDATION | INHIBITORS | ARYLBORONIC ACIDS | WATER | Quinazolines - chemical synthesis | Molecular Structure | Copper - chemistry | Catalysis | Quinazolines - chemistry | Pyrimidines | Chemical properties | Research | Copper | Chemical synthesis
Journal Article
Organic Letters, ISSN 1523-7060, 07/2015, Volume 17, Issue 14, pp. 3434 - 3437
A Pd(OAc)2-catalyzed divergent synthesis of multisubstituted imidazoles and quinazolines from N-allylamidines has been developed. In the presence of oxidant O2... 
Quinazolines - chemical synthesis | Acetates - chemistry | Organometallic Compounds - chemistry | Molecular Structure | Catalysis | Imidazoles - chemical synthesis | Amidines - chemistry | Quinazolines - chemistry | Microwaves
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 06/2014, Volume 79, Issue 12, pp. 5847 - 5851
Journal Article
Inorganic Chemistry, ISSN 0020-1669, 05/2016, Volume 55, Issue 9, pp. 4595 - 4605
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 06/2013, Volume 78, Issue 11, pp. 5700 - 5704
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 10/2019, Volume 25, Issue 57, pp. 13109 - 13113
The quinazoline scaffold is prevalent in pharmaceutically relevant molecules that show diverse biological activities. Herein, we report an efficient “on‐water”... 
cascade reactions | catalysis | palladium | quinazolines | on-water synthesis | Palladium | Chemical synthesis | Scaffolds | Substrates | Functional groups
Journal Article