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quinazolinones - chemical synthesis (333) 333
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biochemistry & molecular biology (132) 132
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cell line, tumor (99) 99
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male (91) 91
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4-quinazolinones (86) 86
quinazolines - chemistry (82) 82
analogs (80) 80
cancer (80) 80
quinazolin-4-ones (80) 80
antineoplastic agents - chemistry (79) 79
aldehydes (72) 72
alkaloids (71) 71
models, molecular (71) 71
discovery (70) 70
cyclization (67) 67
dose-response relationship, drug (65) 65
acid (62) 62
female (62) 62
cell proliferation - drug effects (60) 60
chemistry, applied (60) 60
molecular docking simulation (60) 60
biochemistry, general (59) 59
quinazolinone derivatives (58) 58
efficient (57) 57
microbial sensitivity tests (57) 57
amines (56) 56
cytotoxicity (56) 56
stereoisomerism (56) 56
apoptosis (54) 54
quinazoline (53) 53
solvent-free conditions (53) 53
efficient synthesis (52) 52
potent (52) 52
heterocycles (51) 51
inhibition (51) 51
drug screening assays, antitumor (50) 50
inhibitory concentration 50 (50) 50
in-vitro (49) 49
enzyme inhibitors - pharmacology (47) 47
cell biology (46) 46
chemistry, physical (44) 44
magnetic resonance spectroscopy (44) 44
4-quinazolinone (43) 43
chemical properties (43) 43
pharmacy (43) 43
water (43) 43
inorganic chemistry (42) 42
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physical chemistry (41) 41
activation (40) 40
2,3-dihydroquinazolin-4-ones (39) 39
catalysts (39) 39
drug discovery (39) 39
heterocyclic compounds (39) 39
molecular docking (39) 39
anti-bacterial agents - pharmacology (38) 38
enzyme inhibitors - chemical synthesis (37) 37
docking (36) 36
cell survival - drug effects (35) 35
pharmacology/toxicology (35) 35
proteins (35) 35
quinazolines (35) 35
quinazolinones - therapeutic use (35) 35
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Journal of the American Chemical Society, ISSN 0002-7863, 08/2011, Volume 133, Issue 30, pp. 11430 - 11433
A Rh(III)-catalyzed protocol for the amidation of anilide and enamide C H bonds with isocyanates has been developed. This method provides direct and efficient... 
QUINAZOLINONES | ALKENES | CATALYSIS | ACTIVATION | RHODIUM | COUPLING REACTIONS | NITRILES | INTERNAL ALKYNES | CHEMISTRY, MULTIDISCIPLINARY | HYDROARYLATION | ACRYLATES | Amides - chemical synthesis | Stereoisomerism | Amides - chemistry | Organometallic Compounds - chemistry | Molecular Structure | Catalysis | Isocyanates - chemistry | Rhodium - chemistry | Index Medicus
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 08/2011, Volume 76, Issue 15, pp. 6362 - 6366
Journal Article
Organic Letters, ISSN 1523-7060, 03/2011, Volume 13, Issue 6, pp. 1274 - 1277
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 10/2011, Volume 76, Issue 19, pp. 7730 - 7736
Journal Article
Organic Letters, ISSN 1523-7060, 02/2012, Volume 14, Issue 4, pp. 1150 - 1153
Cul/4-hydroxy-L-proline catalyzed coupling of N-substituted o-bromobenzamides with formamide takes place at 80 degrees C, affording 3-substituted... 
QUINAZOLIN-4(3H)-ONES | HETEROCYCLES | ANTICANCER AGENTS | CHEMISTRY, ORGANIC | CONDENSATION | DICTYOQUINAZOL-A | 1,3-DIHYDROBENZIMIDAZOL-2-ONES | INHIBITORS | FACILE | CYCLIZATION | ACCESS | Quinazolinones - chemical synthesis | Molecular Structure | Copper - chemistry | Catalysis | Amination | Cyclization | Index Medicus
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 06/2014, Volume 79, Issue 11, pp. 5082 - 5087
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 11/2012, Volume 77, Issue 21, pp. 9473 - 9486
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2016, Volume 121, pp. 410 - 421
A new series of 2-substituted mercapto-4(3 )-quinazolinone were synthesized and assessed for anti-inflammatory and analgesic activities and inhibition of... 
Docking study | Synthesis | 2-Mercapto-4(3H)-quinazolinone | Cyclooxygenase-1/cyclooxygenase-2 inhibition assay | Anti-inflammatory activities | inhibition assay | Cyclooxygenase-1/cyclooxygenase-2 | SELECTIVE-INHIBITION | DESIGN | CHEMISTRY, MEDICINAL | CYCLOOXYGENASE-2 | ANALOGS | ANTITUMOR-ACTIVITY | DRUGS | BIOLOGICAL EVALUATION | DERIVATIVES | PROSTAGLANDIN SYNTHESIS | QUINAZOLINES | Analgesics - pharmacology | Analgesics - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Cyclooxygenase 2 Inhibitors - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Analgesics - chemical synthesis | Cyclooxygenase 1 - chemistry | Cyclooxygenase 2 Inhibitors - metabolism | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Quinazolinones - pharmacology | Cyclooxygenase 2 Inhibitors - chemical synthesis | Chemistry Techniques, Synthetic | Cyclooxygenase 2 Inhibitors - pharmacology | Cyclooxygenase 2 - chemistry | Quinazolinones - chemical synthesis | Animals | Analgesics - chemistry | Cyclooxygenase 2 - metabolism | Protein Conformation | Mice | Molecular Docking Simulation | Quinazolinones - chemistry | Cyclooxygenase 1 - metabolism | Quinazolinones - metabolism | Drugstores | COX-2 inhibitors | Pharmacy | Diclofenac | Index Medicus
Journal Article
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 2013, Volume 78, Issue 11, pp. 5700 - 5704
Journal Article
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 07/2015, Volume 80, Issue 14, pp. 7099 - 7107
Journal Article
Journal Article
Organic Letters, ISSN 1523-7060, 08/2013, Volume 15, Issue 15, pp. 4006 - 4009
Insertion reactions of an in situ generated arynes to a variety of suitably substituted 1,3-quinazolin-4-ones have been demonstrated for a new efficient... 
HETEROCYCLES | ARYLATION | BONDS | CHEMISTRY | CHEMISTRY, ORGANIC | EFFICIENT | DERIVATIVES | TRYPTANTHRIN | BENZYNE | ALKALOIDS | Quinazolinones - chemical synthesis | Biological Products - chemistry | Molecular Structure | Quinazolinones - chemistry | Stereoisomerism | Quinazolines - chemistry | Index Medicus
Journal Article
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