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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 05/2017, Volume 61, Issue 5
para-Aminosalicylic acid (PAS) is a second-line antituberculosis drug that has been used to treat multidrug-resistant and extensively drug-resistant... 
MYCOBACTERIUM-TUBERCULOSIS | METHOTREXATE | ELIMINATION | MICROBIOLOGY | GENETIC-VARIANTS | antituberculosis drug | ORGANIC CATION TRANSPORTERS | 22 ANTITUBERCULOSIS DRUGS | drug-drug interactions | THERAPY | PHARMACOKINETICS | membrane transporter | RESISTANCE | PHARMACOLOGY & PHARMACY | ANION TRANSPORTER | Octamer Transcription Factor-1 - antagonists & inhibitors | Organic Anion Transport Protein 1 - metabolism | Proton Pump Inhibitors - pharmacology | Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors | Humans | Naproxen - pharmacology | Organic Cation Transporter 2 - antagonists & inhibitors | Organic Cation Transporter 2 - metabolism | Aminosalicylic Acid - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Aminosalicylic Acid - pharmacokinetics | Organic Anion Transporters, Sodium-Independent - metabolism | HEK293 Cells | ATP-Binding Cassette Transporters - metabolism | Biological Transport - drug effects | Cell Line | Organic Anion Transport Protein 1 - antagonists & inhibitors | Ibuprofen - pharmacology | Antitubercular Agents - pharmacology | Probenecid - pharmacology | Quinidine - pharmacology | Verapamil - pharmacology | Antitubercular Agents - pharmacokinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 - antagonists & inhibitors | Solute Carrier Organic Anion Transporter Family Member 1b1 - metabolism | Drug Interactions - physiology | Cimetidine - pharmacology | Aminosalicylic Acid - pharmacology | Biological Transport - physiology | Rifampin - pharmacology | Antitubercular Agents - metabolism | Octamer Transcription Factor-1 - metabolism
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 07/2016, Volume 68, Issue 7, pp. 883 - 889
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e89985
Dextromethorphan is an antitussive with a high margin of safety that has been hypothesized to display rapid-acting antidepressant activity based on... 
DEPRESSION | LIGANDS | NOREPINEPHRINE | BEHAVIORAL DESPAIR | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | MICE | SEROTONIN | RAT-BRAIN | FORCED SWIMMING TEST | BINDING | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Dextromethorphan - pharmacology | Cytochrome P-450 Enzyme Inhibitors | Receptors, N-Methyl-D-Aspartate - metabolism | Cytochrome P-450 Enzyme System - metabolism | Behavior, Animal - physiology | Male | Adrenergic alpha-Antagonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Quinidine - pharmacology | Receptors, sigma - antagonists & inhibitors | Piperazines - pharmacology | Ethylenediamines - pharmacology | Dose-Response Relationship, Drug | Swimming - physiology | Animals | Protein Binding | Behavior, Animal - drug effects | Antidepressive Agents - pharmacology | Mice | Kinetics | Ketamine - pharmacology | Receptors, sigma - metabolism | Methyl aspartate | Dextromethorphan | Antidepressants | Analysis | Cytochrome | Glutamic acid receptors (ionotropic) | Glutamic acid receptors | Kinases | Proteins | Receptors | Metabolites | Rodents | Pretreatment | Pharmaceutical sciences | Binding | Dopamine | Serotonin | Saturation | Cytochrome P450 | Health psychology | N-Methyl-D-aspartic acid receptors | Pharmacology | Bioavailability | Metabolism | Pentazocine | Medicine | Studies | Hypotheses | Ketamine | Quinidine | Ligands | Psychiatry
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/1998, Volume 18, Issue 3, pp. 868 - 877
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2003, Volume 278, Issue 30, pp. 27406 - 27412
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e69394
We have reported that the P-gp substrate digoxin required basolateral and apical uptake transport in excess of that allowed by digoxin passive permeability (as... 
MEMBRANE TRANSPORTERS | IN-VITRO | EFFLUX | MULTIDISCIPLINARY SCIENCES | CONFLUENT MONOLAYER | GLYCOPROTEIN | CANDIDATES | PHARMACEUTICAL DRUGS | IDENTIFICATION | CACO-2 CELLS | MDCKII-HMDR1 CELLS | Vinblastine - metabolism | Digoxin - metabolism | Cyclosporine - pharmacology | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Ketoconazole - metabolism | Ketoconazole - pharmacology | Carbamates - metabolism | Madin Darby Canine Kidney Cells | Digoxin - antagonists & inhibitors | Cyclosporine - metabolism | Carbamates - pharmacology | Caco-2 Cells | Quinidine - metabolism | Tetrahydroisoquinolines - pharmacology | Gene Expression | Acridines - metabolism | Loperamide - pharmacology | Quinidine - pharmacology | Sulfonamides - pharmacology | Animals | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Tetrahydroisoquinolines - metabolism | Acridines - pharmacology | Cell Membrane Permeability - drug effects | Dogs | Sulfonamides - metabolism | Protein Binding | Loperamide - metabolism | Vinblastine - pharmacology | Kinetics | Loperamide | Permeability | Ketoconazole | Digoxin | Analysis | Monomolecular films | Drugs | Biotechnology | Cyclosporins | Membrane permeability | Biochemistry | Biology | Kinases | MDR1 protein | Inhibition | P-Glycoprotein | Dimerization | Efflux | Enzymes | Vinblastine | Glycoproteins | Metabolism | Substrates | Quinidine | Cell lines | Verapamil | Transport | Amprenavir | Transporter | Cancer | Pharmaceuticals
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 10/2000, Volume 68, Issue 4, pp. 401 - 411
Journal Article