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Blood, ISSN 0006-4971, 09/2010, Volume 116, Issue 10, pp. 1685 - 1697
We evaluated human CD8(+) T-cell responses generated by targeting antigens to dendritic cells (DCs) through various lectin receptors. We found the... 
NONHUMAN-PRIMATES | DEC-205 RECEPTOR | CYTOKINE PRODUCTION | C-TYPE LECTIN | HIV GAG PROTEIN | IMMUNE-RESPONSES | IN-VIVO | HEMATOLOGY | INHIBITORY MOTIF | SURFACE-RECEPTOR | LANGERHANS CELLS | CD8-Positive T-Lymphocytes - cytology | Membrane Glycoproteins - metabolism | Monocytes - cytology | Dendritic Cells - immunology | Humans | Lectins, C-Type - immunology | Neoplasm Proteins - immunology | Monocytes - metabolism | Monocytes - immunology | Quinolines - pharmacology | Lectins, C-Type - metabolism | Cross-Priming - drug effects | Flow Cytometry | Langerhans Cells - immunology | CD8-Positive T-Lymphocytes - metabolism | Membrane Glycoproteins - immunology | Receptors, Immunologic - immunology | Antibodies, Monoclonal - immunology | B-Lymphocytes - metabolism | Dendritic Cells - metabolism | Toll-Like Receptor 8 - agonists | Toll-Like Receptor 7 - agonists | B-Lymphocytes - cytology | Antigens, Neoplasm - immunology | Cells, Cultured | Animals | B-Lymphocytes - immunology | Cross-Priming - immunology | Antigens - immunology | MART-1 Antigen | Dendritic Cells - cytology | Mice | Mice, Inbred BALB C | Thiazoles - pharmacology | CD8-Positive T-Lymphocytes - immunology | gag Gene Products, Human Immunodeficiency Virus - immunology | Langerhans Cells - metabolism | Langerhans Cells - cytology | Receptors, Immunologic - metabolism | Immunobiology
Journal Article
PLoS Pathogens, ISSN 1553-7366, 08/2013, Volume 9, Issue 8, p. e1003597
In contrast to pathogenic HIV/SIV infections of humans and rhesus macaques (RMs), natural SIV infection of sooty mangabeys (SMs) is typically non-pathogenic... 
AFRICAN-GREEN MONKEYS | CD4(+) T-CELLS | NONPATHOGENIC SIV INFECTION | MICROBIOLOGY | REGULATORY FACTOR-7 | PLASMACYTOID DENDRITIC CELLS | ANTIVIRAL RESPONSE | VIROLOGY | LENTIVIRAL INFECTIONS | TOLL-LIKE RECEPTORS | IMMUNODEFICIENCY VIRUS-INFECTION | MEDIATED SUPPRESSION | PARASITOLOGY | Cell Nucleus - immunology | RNA, Messenger - immunology | Interferon-beta - immunology | Dendritic Cells - immunology | Humans | Cercocebus atys | Male | Interferon Regulatory Factor-7 - genetics | Mutation, Missense | Leukocytes, Mononuclear - virology | Quinolines - pharmacology | HIV Infections - immunology | Signal Transduction - immunology | Simian Immunodeficiency Virus - genetics | Interferon-alpha - genetics | DNA Mutational Analysis | Leukocytes, Mononuclear - immunology | Toll-Like Receptor 7 - immunology | Simian Acquired Immunodeficiency Syndrome - genetics | Interferon-beta - genetics | Female | Dendritic Cells - virology | Active Transport, Cell Nucleus - genetics | Simian Immunodeficiency Virus - immunology | Toll-Like Receptor 7 - agonists | Toll-Like Receptor 7 - genetics | HIV Infections - genetics | RNA, Messenger - genetics | Exons - genetics | Imidazoles - pharmacology | Interferon Regulatory Factor-7 - immunology | Signal Transduction - genetics | HIV-1 - genetics | Interferon-alpha - immunology | HIV-1 - immunology | Animals | Cell Nucleus - genetics | Simian Acquired Immunodeficiency Syndrome - immunology | Active Transport, Cell Nucleus - immunology | Amino Acid Substitution | Exons - immunology | Medical research | AIDS | Interferon | Human immunodeficiency virus | HIV | Acquired immune deficiency syndrome
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2014, Volume 193, Issue 2, pp. 627 - 634
Accumulating evidence suggests elements within tumors induce exhaustion of effector T cells and infiltration of immunosuppressive regulatory T cells (Tregs),... 
FLAGELLIN | STIMULATION | IMMUNE-RESPONSES | SUPPRESSIVE FUNCTION | IN-VIVO | TOLL-LIKE RECEPTORS | GENERATION | IMMUNOLOGY | EXPRESSION | CANCER | FOXP3 | Forkhead Transcription Factors - immunology | Tumor Necrosis Factor-alpha - metabolism | Leukocytes, Mononuclear - metabolism | T-Lymphocytes, Regulatory - metabolism | Lipopeptides - pharmacology | Humans | Interferon-gamma - metabolism | Quinolines - pharmacology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Flagellin - pharmacology | Lymphocyte Activation - immunology | Forkhead Transcription Factors - metabolism | Leukocytes, Mononuclear - immunology | Tumor Necrosis Factor-alpha - immunology | CD8-Positive T-Lymphocytes - metabolism | Interleukin-10 - metabolism | Killer Cells, Natural - immunology | Adult | Toll-Like Receptors - metabolism | Interleukin-6 - metabolism | B-Lymphocytes - metabolism | Leukocytes, Mononuclear - drug effects | Toll-Like Receptors - immunology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Imidazoles - pharmacology | Toll-Like Receptors - agonists | B-Lymphocytes - drug effects | T-Lymphocytes, Regulatory - drug effects | B-Lymphocytes - immunology | Analysis of Variance | Lymphocyte Activation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Interferon-gamma - immunology | Interleukin-6 - immunology | Lipopolysaccharides - pharmacology | Cell Proliferation - drug effects | Killer Cells, Natural - drug effects | Thiazoles - pharmacology | Killer Cells, Natural - metabolism | CD8-Positive T-Lymphocytes - immunology | Interleukin-10 - immunology | CD4-Positive T-Lymphocytes - drug effects
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2017, Volume 199, Issue 1, pp. 253 - 262
Chemokines have been shown to play immune-modulatory functions unrelated to steering cell migration. CXCL4 is a chemokine abundantly produced by activated... 
Journal Article | Immunology | MHC CLASS-I | IMMUNE-RESPONSES | ENDOTHELIAL-CELLS | TOLL-LIKE RECEPTORS | SUBCELLULAR-LOCALIZATION | ANTIGEN PRESENTATION | IMMUNOLOGY | SYSTEMIC-SCLEROSIS | CHEMOKINE PLATELET-FACTOR-4 | PLATELET FACTOR-IV | CROSS-PRESENTATION | Antigens, CD - immunology | B7-2 Antigen - genetics | Immunoglobulins - immunology | Escherichia coli Infections - prevention & control | Interleukin-12 - genetics | Coculture Techniques | Dendritic Cells - immunology | Humans | Platelet Factor 4 - immunology | Dendritic Cells - physiology | Immunoglobulins - genetics | Antigens, CD - genetics | CD4-Positive T-Lymphocytes - physiology | Quinolines - pharmacology | CD4-Positive T-Lymphocytes - immunology | Platelet Factor 4 - pharmacology | Tumor Necrosis Factor-alpha - immunology | Dendritic Cells - drug effects | Cell Differentiation | Membrane Glycoproteins - immunology | B7-2 Antigen - immunology | Escherichia coli - physiology | Poly I-C - pharmacology | Lymphocyte Activation | Cells, Cultured | Escherichia coli Infections - microbiology | Imidazoles - pharmacology | CD8-Positive T-Lymphocytes - physiology | Membrane Glycoproteins - genetics | Phenotype | CD8-Positive T-Lymphocytes - drug effects | Interleukin-12 - immunology | Escherichia coli Infections - immunology | Genes, MHC Class I | Platelet Factor 4 - metabolism | Thiazoles - pharmacology | CD8-Positive T-Lymphocytes - immunology | CD4-Positive T-Lymphocytes - drug effects | Cell proliferation | CD86 antigen | Leukocyte migration | CD8 antigen | Antigen processing | Stimulation | Lymphocytes T | Interleukin 4 | Cell activation | Lymphocytes | Toll-like receptors | Immune system | Immune response | Dendritic cells | Immunomodulation | Secretion | Interleukin 12 | Exposure | T cell receptors | Poly (I:C) | CD4 antigen | CD83 antigen | Monocytes | Major histocompatibility complex | Systemic sclerosis | Internalization | γ-Interferon | Ligands | Interferon | Platelets | Cell migration | Chemokines
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 02/2017, Volume 19, Issue 1, p. 39
Background: Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of... 
IFN inducible genes | Monocytes | Toll-like receptor 8 | EBV reactivation | Innate immune response | Systemic sclerosis | CELLS | RECOGNITION | SUBSETS | LUPUS-ERYTHEMATOSUS | RHEUMATOLOGY | CIRCULATING MONOCYTES | TLR AGONISTS | SCLERODERMA | DISEASE | GENE-EXPRESSION | EBV | Herpesvirus 4, Human - genetics | Gene Expression - drug effects | Virus Replication - genetics | Humans | Middle Aged | Immunity, Innate - genetics | Male | Monocytes - metabolism | Monocytes - immunology | Quinolines - pharmacology | Host-Pathogen Interactions - immunology | Young Adult | Toll-Like Receptor 8 - immunology | Gene Expression - immunology | Epstein-Barr Virus Infections - genetics | Adult | Female | Epstein-Barr Virus Infections - virology | Epstein-Barr Virus Infections - immunology | Herpesvirus 4, Human - physiology | Scleroderma, Systemic - metabolism | Cells, Cultured | Herpesvirus 4, Human - immunology | Scleroderma, Systemic - genetics | Gene Expression Profiling - methods | Virus Replication - immunology | Scleroderma, Systemic - immunology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Immunity, Innate - immunology | Monocytes - virology | Host-Pathogen Interactions - genetics | Toll-Like Receptor 8 - genetics | Cell Line, Tumor | Aged | Thiazoles - pharmacology | Virus Replication - physiology | Toll-Like Receptor 8 - metabolism
Journal Article
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 10/2012, Volume 111, Issue 10, pp. 1297 - 1307
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2009, Volume 123, Issue 5, pp. 1026 - 1033
Journal Article
Immunology, ISSN 0019-2805, 11/2011, Volume 134, Issue 3, pp. 257 - 269
Summary Interferon‐α (IFN‐α) produced at high levels by human plasmacytoid dendritic cells (pDCs) can specifically regulate B‐cell activation to Toll‐like... 
dendritic cells | B cells | Type I interferon/toll‐like receptors | CpGDNA | adjuvants | plasmacytoid | Type I interferon/toll-like receptors | Adjuvants | Plasmacytoid | Dendritic cells | NATURAL-KILLER-CELLS | ACTIVATION | HIV-1 ENV TRIMERS | IMMUNOLOGY | VACCINE ADJUVANTS | BLOOD MONONUCLEAR-CELLS | I INTERFERON | MEMORY | TLR LIGANDS | CPG OLIGONUCLEOTIDES | INNATE IMMUNITY | Interferon-alpha - pharmacology | Dendritic Cells - immunology | Humans | Macaca mulatta - immunology | Immunoglobulin M - immunology | Quinolines - pharmacology | Toll-Like Receptor 9 - agonists | Immunoglobulin M - metabolism | Toll-Like Receptor 9 - immunology | Toll-Like Receptor 8 - immunology | Macaca mulatta - metabolism | Flow Cytometry | Toll-Like Receptor 7 - immunology | Dendritic Cells - drug effects | Toll-Like Receptors - metabolism | B-Lymphocytes - metabolism | Dendritic Cells - metabolism | Toll-Like Receptor 8 - agonists | Toll-Like Receptor 7 - agonists | Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology | Antigens, CD20 - immunology | Interferon-alpha - metabolism | Toll-Like Receptor 7 - metabolism | Enzyme-Linked Immunosorbent Assay | Toll-Like Receptors - immunology | Cells, Cultured | Imidazoles - pharmacology | Antigens, CD20 - metabolism | Toll-Like Receptors - agonists | Interferon-alpha - immunology | B-Lymphocytes - drug effects | Cell Differentiation - immunology | Animals | B-Lymphocytes - immunology | Cell Differentiation - drug effects | Tumor Necrosis Factor Receptor Superfamily, Member 7 - metabolism | Cell Proliferation - drug effects | Oligodeoxyribonucleotides - pharmacology | Toll-Like Receptor 9 - metabolism | Toll-Like Receptor 8 - metabolism | Primates | Immunoglobulins | Biological response modifiers | Analysis | Medical research | Ligands | T cell receptors | Immune system | Type I interferon | toll-like receptors | Original
Journal Article
Journal of Neuroimmunology, ISSN 0165-5728, 2009, Volume 214, Issue 1, pp. 67 - 77
Journal Article