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Journal of the American Chemical Society, ISSN 0002-7863, 05/2010, Volume 132, Issue 20, pp. 6908 - 6909
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2016, Volume 291, Issue 13, pp. 6610 - 6624
Pseudomonas aeruginosa produces a number of alkylquinolone-type secondary metabolites best known for their antimicrobial effects and involvement in cell-cell... 
FabH | 2-alkyl-4(1H)-quinolones | quorum sensing | condensing enzyme | BIOCHEMISTRY & MOLECULAR BIOLOGY | Pseudomonas quinolone signal | ANTHRANILATE | aeruginosa | PROTEIN SYNTHASE-III | IDENTIFICATION | MOLECULES | Pseudomonas aeruginosa (P | CHALCONE SYNTHASE | secondary metabolism | CATALYTIC CYSTEINE | biosynthesis | crystal structure | COEFFICIENTS | ABSORPTION | 2,4-DIHYDROXYQUINOLINE | COMMUNICATION | Protein Multimerization | Bacterial Proteins - chemistry | Molecular Sequence Data | Crystallography, X-Ray | Protein Subunits - metabolism | 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase - antagonists & inhibitors | Pseudomonas aeruginosa - enzymology | Anti-Bacterial Agents - chemistry | Enzyme Inhibitors - chemistry | Escherichia coli - metabolism | 4-Quinolones - chemistry | Acyl Coenzyme A - metabolism | Binding Sites | Binding, Competitive | Recombinant Proteins - metabolism | Amino Acid Sequence | Bacterial Proteins - antagonists & inhibitors | Catalytic Domain | Biocatalysis | Protein Structure, Secondary | Models, Molecular | Recombinant Proteins - chemistry | Acyl Coenzyme A - chemistry | 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase - chemistry | Pseudomonas aeruginosa - chemistry | Sequence Alignment | 4-Quinolones - metabolism | Acetophenones - chemistry | Aminobenzoates - chemistry | Escherichia coli - genetics | Aminobenzoates - metabolism | Protein Binding | Bacterial Proteins - metabolism | Ligands | Protein Subunits - antagonists & inhibitors | Protein Subunits - chemistry | Kinetics | 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase - metabolism | Pseudomonas aeruginosa (P. aeruginosa) | Enzymology
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 2826 - 7
... Sciences, University of Shizuoka, Shizuoka 422-8526, Japan. 2 Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA.... 
ALKALOID BIOSYNTHESIS | VIRIDICATIN | ASPERGILLUS-NIDULANS | MECHANISTIC INSIGHTS | MULTIDISCIPLINARY SCIENCES | DIOXYGENASE | PENICILLIUM-CYCLOPIUM | CONIDIOSPORES | CYCLOPENASE | DERIVATIVES | SOFTWARE | Fungal Proteins - chemistry | Aspergillus nidulans - genetics | Carbon Dioxide - chemistry | Hydroxyquinolines - chemistry | Zinc - metabolism | Substrate Specificity | Crystallography, X-Ray | Zinc - chemistry | Aspergillus nidulans - metabolism | Quinolones - chemistry | Aspergillus nidulans - chemistry | Isocyanates - metabolism | Cloning, Molecular | Escherichia coli - metabolism | Protein Interaction Domains and Motifs | Alkaloids - biosynthesis | Binding Sites | Methylamines - chemistry | Methylamines - metabolism | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Gene Expression | Carbon Dioxide - metabolism | Genetic Vectors - chemistry | Hemocyanins - genetics | Hydroxyquinolines - metabolism | Quinolones - metabolism | Genetic Vectors - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Biosynthetic Pathways | Recombinant Proteins - genetics | Fungal Proteins - genetics | Isocyanates - chemistry | Cyclization | Escherichia coli - genetics | Hemocyanins - metabolism | Protein Binding | Hemocyanins - chemistry | Kinetics | Alkaloids - chemistry | Fungal Proteins - metabolism | Proteins | Isocyanates | Alkaloids | Methylamine | Metabolites | Methyl isocyanate | Carbon dioxide | Computer applications | Biosynthesis | Contraction
Journal Article
Nature Chemistry, ISSN 1755-4330, 07/2009, Volume 1, Issue 4, pp. 302 - 309
Journal Article
Journal Article
ACS Chemical Biology, ISSN 1554-8929, 12/2013, Volume 8, Issue 12, pp. 2660 - 2668
Quinolones, which target gyrase and topoisomerase IV, are the most widely prescribed antibacterials worldwide. Unfortunately, their use is threatened by the... 
IN-VITRO | EUKARYOTIC TOPOISOMERASE | CLINICAL-APPLICATIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | DNA GYRASE | BACILLUS-ANTHRACIS | FLUOROQUINOLONE RESISTANCE | MUTATIONS | CLEAVAGE | II-ALPHA | DNA Topoisomerase IV - metabolism | DNA, Bacterial - metabolism | Species Specificity | Humans | DNA, Bacterial - chemistry | Quinolones - pharmacology | Structure-Activity Relationship | Antigens, Neoplasm - chemistry | Bacillus anthracis - enzymology | DNA-Binding Proteins - metabolism | Quinolones - chemistry | Anti-Bacterial Agents - chemistry | DNA Topoisomerases, Type II - chemistry | Water - chemistry | Antigens, Neoplasm - metabolism | Bacillus anthracis - drug effects | DNA Topoisomerase IV - genetics | Drug Resistance, Bacterial - drug effects | Bacillus anthracis - genetics | Quinazolinones - pharmacology | Bacillus anthracis - chemistry | Recombinant Proteins - metabolism | Antigens, Neoplasm - genetics | DNA Topoisomerase IV - chemistry | DNA Topoisomerases, Type II - metabolism | Recombinant Proteins - chemistry | Magnesium - metabolism | Recombinant Proteins - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | DNA Cleavage - drug effects | Magnesium - chemistry | Cations, Divalent | DNA Topoisomerase IV - antagonists & inhibitors | DNA Topoisomerases, Type II - genetics | Anti-Bacterial Agents - pharmacology | Quinazolinones - chemistry | Kinetics | Mutation
Journal Article
Nature (London), ISSN 1476-4687, 2010, Volume 466, Issue 7309, pp. 935 - 940
Journal Article
Journal Article