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Journal Article
Journal Article
Expert Review of Anti-Infective Therapy, ISSN 1478-7210, 2014, Volume 12, Issue 7, pp. 763 - 773
About 2% of the world's population is estimated to be chronically infected with hepatitis C virus (HCV). These chronic carriers are at risk of developing liver... 
Daclatasvir | MK-8742 | Ombitasvir | Interferon-free | Ledipasvir | MK-5172 | Asunaprevir | ABT-450 | Sofosbuvir | Dasabuvir | CONTROLLED-TRIAL | PLUS RIBAVIRIN | LIVER-TRANSPLANTATION | ombitasvir | asunaprevir | HCV INFECTION | daclatasvir | interferon-free | ledipasvir | sofosbuvir | SUSTAINED VIROLOGICAL RESPONSE | PROTEASE INHIBITOR | TREATMENT OPTIONS | GENOTYPE 1 INFECTION | PHARMACOLOGY & PHARMACY | dasabuvir | CHRONIC VIRAL-HEPATITIS | DISEASE PROGRESSION | Uridine Monophosphate - administration & dosage | Quinoxalines - adverse effects | Anilides - therapeutic use | Isoquinolines - adverse effects | Hepatitis C - drug therapy | Anilides - adverse effects | Humans | Imidazoles - administration & dosage | Benzofurans - administration & dosage | Carbamates - administration & dosage | Uracil - administration & dosage | Ribavirin - administration & dosage | Uridine Monophosphate - adverse effects | Imidazoles - therapeutic use | Hepatitis C - prevention & control | Quinoxalines - therapeutic use | Uridine Monophosphate - therapeutic use | Disease Eradication | Benzofurans - therapeutic use | Quinoxalines - administration & dosage | Antiviral Agents - therapeutic use | Imidazoles - adverse effects | Ribavirin - therapeutic use | Uracil - therapeutic use | Clinical Trials as Topic | Macrocyclic Compounds - adverse effects | Antiviral Agents - administration & dosage | Benzofurans - adverse effects | Macrocyclic Compounds - therapeutic use | Uracil - adverse effects | Anilides - administration & dosage | Sulfonamides - therapeutic use | Ribavirin - adverse effects | Antiviral Agents - adverse effects | Uridine Monophosphate - analogs & derivatives | Isoquinolines - therapeutic use | Sulfonamides - adverse effects | Carbamates - adverse effects | Macrocyclic Compounds - administration & dosage | Carbamates - therapeutic use | Hepacivirus | Isoquinolines - administration & dosage | Drug Combinations | Sulfonamides - administration & dosage | Uracil - analogs & derivatives
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2009, Volume 66, Issue 2, pp. 185 - 190
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2017, Volume 67, Issue 2, pp. 263 - 271
Journal Article
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2010, Volume 335, Issue 3, pp. 807 - 816
Accumulating evidence suggests that acetylcholine nicotinic systems may contribute importantly to the abuse-related effects of d-methamphetamine (d-MA). The... 
DIHYDRO-BETA-ERYTHROIDINE | ACETYLCHOLINE-RECEPTORS | SQUIRREL-MONKEYS | DOPAMINE RELEASE | BEHAVIORAL SENSITIZATION | PHARMACOLOGY & PHARMACY | MONOAMINE TRANSPORTERS | STIMULUS PROPERTIES | ALPHA-BUNGAROTOXIN | NUCLEUS-ACCUMBENS | UPTAKE INHIBITORS | Nicotinic Antagonists - administration & dosage | Cholinergic Agents - administration & dosage | Cholinergic Agents - pharmacology | Varenicline | Pentobarbital - administration & dosage | Pentobarbital - pharmacology | Male | Nicotinic Antagonists - pharmacology | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Drug Interactions | Muscarinic Antagonists - pharmacology | Discrimination (Psychology) | Mecamylamine - pharmacology | Behavior, Animal - drug effects | Nicotinic Agonists - pharmacology | Discrimination Learning | Methamphetamine - pharmacology | Dopamine Agonists - pharmacology | Mecamylamine - administration & dosage | Dextroamphetamine - pharmacology | Quinoxalines - administration & dosage | Reinforcement (Psychology) | Rats | Benzazepines - pharmacology | Rats, Sprague-Dawley | Muscarinic Antagonists - administration & dosage | Nicotinic Agonists - administration & dosage | Animals | Cholinesterase Inhibitors - administration & dosage | Cholinesterase Inhibitors - pharmacology | Methamphetamine - administration & dosage | Dopamine Agonists - administration & dosage | Conditioning, Operant | Benzazepines - administration & dosage | Dextroamphetamine - administration & dosage
Journal Article
Cephalalgia, ISSN 0333-1024, 7/2018, Volume 38, Issue 8, pp. 1471 - 1484
Background Nitric oxide (NO) has been heavily implicated in migraine. Nitroglycerin is a prototypic NO-donor, and triggers migraine in humans. However,... 
cGMP | nitric oxide | Trigeminovascular pain | mouse model | CGRP | OXIDATIVE STRESS | GENE-RELATED PEPTIDE | C-FOS | NITRIC-OXIDE SYNTHASE | MITOCHONDRIAL ALDEHYDE DEHYDROGENASE | CORTICAL SPREADING DEPRESSION | FOS EXPRESSION | GLYCERYL TRINITRATE INFUSION | NEUROSCIENCES | CLINICAL NEUROLOGY | EXPERIMENTAL-MODEL | HEADACHE | Hyperalgesia - chemically induced | Oxadiazoles - administration & dosage | Soluble Guanylyl Cyclase - metabolism | Allosteric Regulation | Propranolol - therapeutic use | Sumatriptan - therapeutic use | Proto-Oncogene Proteins c-fos - biosynthesis | Sumatriptan - administration & dosage | Topiramate - therapeutic use | Anticonvulsants - administration & dosage | Male | Nitric Oxide - adverse effects | Molecular Targeted Therapy | Nitroglycerin - pharmacology | Enzyme Inhibitors - administration & dosage | Migraine Disorders - chemically induced | Migraine Disorders - enzymology | Propranolol - administration & dosage | Female | Nitric Oxide Donors - pharmacology | Adrenergic beta-Antagonists - administration & dosage | Adrenergic beta-Antagonists - therapeutic use | Disease Models, Animal | Quinoxalines - therapeutic use | Topiramate - administration & dosage | Enzyme Inhibitors - metabolism | Quinoxalines - administration & dosage | Mice, Inbred C57BL | Anticonvulsants - therapeutic use | Quinoxalines - metabolism | Soluble Guanylyl Cyclase - physiology | Serotonin 5-HT1 Receptor Agonists - therapeutic use | Enzyme Inhibitors - therapeutic use | Migraine Disorders - drug therapy | Oxadiazoles - therapeutic use | Animals | Hyperalgesia - drug therapy | Migraine Disorders - etiology | Calcitonin Gene-Related Peptide - biosynthesis | Serotonin 5-HT1 Receptor Agonists - administration & dosage | Mice | Nitric Oxide - metabolism | Hyperalgesia - enzymology | Oxadiazoles - metabolism | trigeminovascular pain
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 12/2007, Volume 176, Issue 11, pp. 1138 - 1145
Rationale: Nitric oxide-independent agonists of soluble guanylate cyclase (sGC) have been developed. Objectives: We tested whether inhalation of novel... 
BAY 41-2272 | BAY 58-2667 | Pulmonary hypertension | BAY 41-8543 | Soluble guanylate cyclase | LARGE POROUS PARTICLES | AUGMENTS | pulmonary hypertension | INHALATION | soluble guanylate cyclase | DELIVERY | INHIBITION | ACTIVATOR | RESPIRATORY SYSTEM | BAY-41-2272 | NITRIC-OXIDE | AWAKE LAMBS | HYPERTENSION | CRITICAL CARE MEDICINE | Oxadiazoles - administration & dosage | Injections, Intravenous | Nitric Oxide - pharmacology | Purinones - administration & dosage | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Oxadiazoles - pharmacology | Lung - metabolism | Pyrazoles - pharmacology | Powders | Pyridines - administration & dosage | Quinoxalines - administration & dosage | Pyrimidines - administration & dosage | Morpholines - administration & dosage | Administration, Inhalation | Morpholines - pharmacology | Phosphodiesterase Inhibitors - pharmacology | Soluble Guanylyl Cyclase | Receptors, Cytoplasmic and Nuclear - agonists | Pyrimidines - pharmacology | Nitric Oxide - administration & dosage | Benzoates - administration & dosage | Particle Size | Phosphodiesterase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Animals | Cyclic GMP - metabolism | Guanylate Cyclase | Lung - drug effects | Aerosols | Benzoates - pharmacology | Purinones - pharmacology | Sheep | Pulmonary Circulation - drug effects | Pyridines - pharmacology | Vasodilation - drug effects | Drug Combinations | H. Pulmonary Vascular Disease
Journal Article