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biochemistry & molecular biology (133) 133
phosphorylation (111) 111
animals (98) 98
cystic fibrosis (97) 97
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cystic fibrosis transmembrane conductance regulator - metabolism (89) 89
transmembrane conductance regulator (85) 85
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adenosine triphosphate - metabolism (45) 45
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cyclic amp-dependent protein kinases - metabolism (27) 27
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mice (26) 26
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congenital, hereditary, and neonatal diseases and abnormalities (24) 24
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protein structure, secondary (22) 22
ion channel gating (21) 21
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respiratory system (21) 21
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Journal Article
Biochemistry, ISSN 0006-2960, 10/2018, Volume 57, Issue 43, pp. 6234 - 6246
The cystic fibrosis transmembrane conductance regulator (CFTR) anion channel, crucial to epithelial salt and water homeostasis, and defective due to mutations... 
TRANSMEMBRANE CONDUCTANCE REGULATOR | R-DOMAIN | ABC TRANSPORTER | HUMAN P-GLYCOPROTEIN | STRUCTURAL BASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYSTIC-FIBROSIS | CHLORIDE CHANNEL | NUCLEOTIDE-BINDING DOMAIN | DELTA-F508 CFTR | ATP-BINDING
Journal Article
NATURE STRUCTURAL & MOLECULAR BIOLOGY, ISSN 1545-9985, 01/2005, Volume 12, Issue 1, pp. 17 - 25
Journal Article
Journal Article
Biochemistry, ISSN 0006-2960, 11/2018, Volume 57, Issue 44, pp. 6278 - 6292
ATP-sensitive potassium (K-ATP) channels in vascular smooth muscle are comprised of four pore-forming Kir6.1 subunits and four copies of the sulfonylurea... 
R-DOMAIN | MOLECULAR-BIOLOGY | CONFORMATIONAL-CHANGES | INTRINSICALLY DISORDERED PROTEIN | EARLY REPOLARIZATION | HELICAL PEPTIDES | BIOCHEMISTRY & MOLECULAR BIOLOGY | K-ATP CHANNEL | SULFONYLUREA RECEPTOR | NUCLEOTIDE-BINDING DOMAIN | SUBUNIT STOICHIOMETRY
Journal Article
Industrial Engineering & Management Systems, ISSN 1598-7248, 2017, Volume 16, Issue 4, pp. 647 - 655
This paper investigates a method for evaluating profitability and risk for multiple investment alternatives, for both cases of consistent return over a planned... 
Multiple Investment Alternatives | Risk | Profitability | Safety | C-R Domain | 산업공학
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 09/2019, Volume 9, Issue 1, pp. 1 - 17
VX-770 (ivacaftor) is approved for clinical use in CF patients bearing multiple CFTR mutations. VX-770 potentiated wildtype CFTR and several disease mutants... 
R-DOMAIN | TRANSMEMBRANE-CONDUCTANCE-REGULATOR | ATP HYDROLYSIS | DELTA-F508 | RESCUE | MULTIDISCIPLINARY SCIENCES | MUTATION | CYSTIC-FIBROSIS | CHLORIDE CHANNEL | NUCLEOTIDE-BINDING DOMAIN | REGION | Protein kinase A | Potentiation | Phosphorylation | Epithelial cells | Mutation | Drug screening | Electrostatic properties | Gating | Oocytes
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2018, Volume 115, Issue 50, pp. 12757 - 12762
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 06/2009, Volume 75, Issue 6, pp. 1430 - 1438
The deletion of Phe-508 (Delta Phe508) constitutes the most prevalent of a number of mutations in the cystic fibrosis transmembrane conductance regulator... 
TRANSMEMBRANE CONDUCTANCE REGULATOR | R-DOMAIN | ABC TRANSPORTER | CHLORIDE-CHANNEL | NUCLEOTIDE-BINDING DOMAINS | PHOSPHORYLATION | POTENTIATES WILD-TYPE | CFTR CHANNELS | PHARMACOLOGY & PHARMACY | CYSTIC-FIBROSIS | ADENYLATE KINASE-ACTIVITY
Journal Article
Nature Reviews Microbiology, ISSN 1740-1526, 12/2010, Volume 8, Issue 12, pp. 843 - 848
Journal Article