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Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 01/2014, Volume 15, Issue 1, pp. 19 - 33
Journal Article
TRENDS IN PHARMACOLOGICAL SCIENCES, ISSN 0165-6147, 02/2014, Volume 35, Issue 2, pp. 103 - 109
The canonical WNT pathway regulates the stability of the proto-oncogene p-catenin and is aberrantly activated in many cancer types. Studies in a wide range of... 
COLON-CANCER | E3 LIGASE | DRIVEN CANCERS REQUIRE | COLORECTAL-CANCER | ONCOGENIC KRAS | IN-VIVO | TUMOR-SUPPRESSOR | PHARMACOLOGY & PHARMACY | R-SPONDIN FAMILY | BETA-CATENIN | MEDIATOR COMPLEX
Journal Article
Journal Article
by Cao, J and Li, C and Wei, XH and Tu, MQ and Zhang, Y and Xu, FW and Xu, YH
MOLECULAR CANCER THERAPEUTICS, ISSN 1535-7163, 07/2018, Volume 17, Issue 7, pp. 1475 - 1485
Cancer stem cells (CSC) that may account for only a small fraction of tumor mass were found to play crucial roles during tumor initiating, progression, and... 
HEPATOCELLULAR-CARCINOMA | ONCOLOGY | PROTEIN-COUPLED RECEPTOR | WNT/BETA-CATENIN | R-SPONDIN | MARKER | COLORECTAL-CANCER | TUMOR | MONOCLONAL-ANTIBODY | IDENTIFICATION | WNT RECEPTORS
Journal Article
Developmental Cell, ISSN 1534-5807, 01/2016, Volume 36, Issue 1, pp. 79 - 93
The WNT signaling enhancer R-spondin3 (RSPO3) is prominently expressed in the vasculature. Correspondingly, embryonic lethality of -deficient mice is caused by... 
vascular regression | RNF213 | angiogenesis | Moyamoya | vascular pruning | RSPO3 | R-spondin | vascular remodeling | WNT | non-canonical WNT pathway | NFAT | CELLS | MOYAMOYA-DISEASE | ANGIOGENESIS | WNT/BETA-CATENIN | PATHWAY | PROLIFERATION | R-SPONDIN3 | DEVELOPMENTAL BIOLOGY | RECEPTORS | BLOOD-BRAIN-BARRIER | EXPRESSION | CELL BIOLOGY
Journal Article
脊髄外科, ISSN 0914-6024, 2018, Volume 32, Issue 3, pp. 275 - 279
Journal Article
Cancer Research, ISSN 0008-5472, 08/2018, Volume 78, Issue 16, pp. 4497 - 4511
R-spondin3 (RSPO3) is a member of a family of secreted proteins that enhance Wnt signaling pathways in diverse processes, including cancer. However, the role... 
EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER CELLS | ONCOLOGY | R-SPONDIN | GENES | BRANCHING MORPHOGENESIS | SELF-RENEWAL | BETA-CATENIN | WNT/BETA-CATENIN PATHWAY | GLAND DEVELOPMENT | LGR4
Journal Article
Genes and Cancer, ISSN 1947-6019, 2015, Volume 6, Issue 9-10, pp. 365 - 366
Journal Article