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Journal of Cell Science, ISSN 0021-9533, 12/2002, Volume 115, Issue 24, pp. 4901 - 4913
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2015, Volume 290, Issue 15, pp. 9363 - 9376
Journal Article
06/2014
One of the hallmarks of postprandial glucose homeostasis is the ability of insulin to promote glucose uptake into skeletal muscles. Insulin achieves this feat... 
Rac | 0487 | Actin | Muscle | GLUT4 | GTPase | Insulin
Dissertation
03/2014
Genetic and epigenetic factors that predispose to ineffective control of subgingival biofilm composition are incompletely understood. The objective of this... 
0567 | Periodontitis | 0982 | Inflammation | Rac GTPases
Dissertation
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 47, pp. 19179 - 19197
Cell adhesion to the extracellular matrix or to surrounding cells plays a key role in cell proliferation and differentiation and is critical for proper tissue... 
Index Medicus | Life Sciences | Biochemistry, Molecular Biology | adhesion | cell proliferation | yes-associated protein (YAP) | integrin | Rac (Rac GTPase) | Cell Biology
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2016, Volume 291, Issue 38, pp. 20042 - 20054
Downstream of receptor tyrosine kinase and G protein-coupled receptor (GPCR) stimulation, the phosphatidylinositol 3,4,5-trisphosphate (PIP3)-dependent Rac... 
RAC-GEF | STIMULATED GLUCOSE-UPTAKE | NUCLEOTIDE-EXCHANGE FACTOR | NEUTROPHIL FUNCTION | insulin | signal transduction | phosphatidylinositol 3-kinase (PI 3-kinase) | BIOCHEMISTRY & MOLECULAR BIOLOGY | PKA | 4,5-trisphosphate-dependent Rac exchanger 1 (PREX1) | Rac (Rac GTPase) | phosphatidylinositol 3 | P-REX1 | p-21-activated kinase (PAK) | BREAST-CANCER CELLS | SKELETAL-MUSCLE | INHIBITION | G protein-coupled receptor (GPCR) | PLECKSTRIN HOMOLOGY | receptor tyrosine kinase | guanine nucleotide exchange factor (GEF) | Cyclic AMP-Dependent Protein Kinases - metabolism | Dinoprostone - pharmacology | Insulin - pharmacology | Guanine Nucleotide Exchange Factors - genetics | Insulin-Like Growth Factor I - pharmacology | Phosphatidylinositol Phosphates - metabolism | p21-Activated Kinases - genetics | Signal Transduction | Humans | p21-Activated Kinases - metabolism | Phosphatidylinositol Phosphates - genetics | Cyclic AMP-Dependent Protein Kinases - genetics | MCF-7 Cells | Guanine Nucleotide Exchange Factors - metabolism | Receptor, Insulin - genetics | Isoproterenol - pharmacology | HEK293 Cells | Receptor, Insulin - metabolism | Phosphorylation - drug effects | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Index Medicus | phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 (PREX1) | Cell Biology
Journal Article
Journal of Experimental Botany, ISSN 0022-0957, 1/2010, Volume 61, Issue 7, pp. 1917 - 1937
Polarized cell expansion plays an important role in plant morphogenesis. Tip growth is a dramatic form of this process, which is widely used as a model to... 
Proteins | Cell growth | Plant growth regulators | Review Papers | Pollen tubes | Gene expression regulation | Root hairs | Genomes | Pollen | Plants | Plant cells | Polarity | Physcomitrella | RAC/ROP signalling | Tip growth | RHO-RELATED GTPASES | POLLEN-TUBE GROWTH | ARABIDOPSIS-THALIANA | POLAR CELL-GROWTH | ACTIVATING PROTEIN | CLOSEST LIVING RELATIVES | ROP GTPASE | tip growth | EXOCYST COMPLEX | PLANT SCIENCES | RAC | RAC-LIKE GTPASES | NUCLEOTIDE-EXCHANGE FACTORS | polarity | ROP signalling | Meristem - cytology | Multigene Family | Guanine Nucleotide Dissociation Inhibitors - chemistry | Molecular Sequence Data | rac GTP-Binding Proteins - metabolism | Phylogeny | rho-Specific Guanine Nucleotide Dissociation Inhibitors | Plant Proteins - chemistry | rac GTP-Binding Proteins - genetics | Plant Proteins - metabolism | Amino Acid Sequence | Guanine Nucleotide Exchange Factors - genetics | Signal Transduction | GTPase-Activating Proteins - chemistry | Rho Guanine Nucleotide Exchange Factors | Sequence Analysis, DNA | Meristem - growth & development | Bryopsida - growth & development | Plant Proteins - genetics | Models, Biological | rac GTP-Binding Proteins - chemistry | Guanine Nucleotide Dissociation Inhibitors - genetics | GTPase-Activating Proteins - genetics | Bryopsida - cytology | Guanine Nucleotide Exchange Factors - chemistry | Index Medicus | Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Biology | Biologi | Natural Sciences
Journal Article
Blood, ISSN 0006-4971, 06/2012, Volume 119, Issue 25, pp. 6118 - 6127
Journal Article
Oncogene, ISSN 0950-9232, 04/2009, Volume 28, Issue 13, pp. 1570 - 1583
The motility of cancer cells in 3D matrices is of two types: mesenchymal motility, in which the cells are elongated and amoeboid motility, in which the cells... 
Amoeboid | Rac | Migration | Invasion | Cancer | Mesenchymal | PERICELLULAR PROTEOLYSIS | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | amoeboid | MECHANISMS | CELL BIOLOGY | ACTIN-RELATED PROTEIN-2 | WAVE2 | MODES | invasion | GTPASES | ONCOLOGY | mesenchymal | GENETICS & HEREDITY | migration | cancer | PLASTICITY | Neoplasms - metabolism | Humans | rac GTP-Binding Proteins - metabolism | rhoA GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - physiology | Cell Shape - genetics | rhoA GTP-Binding Protein - genetics | Cell Culture Techniques - methods | Cell Movement - genetics | Cell Movement - physiology | Neoplasms - genetics | rac GTP-Binding Proteins - genetics | Collagen - pharmacology | Tumor Cells, Cultured | rac GTP-Binding Proteins - physiology | Cell Adhesion - genetics | Neoplasm Invasiveness | rho GTP-Binding Proteins - genetics | Mutant Proteins - metabolism | Signal Transduction - genetics | Mutant Proteins - physiology | rho GTP-Binding Proteins - physiology | rac1 GTP-Binding Protein - physiology | Cell Adhesion - physiology | rho GTP-Binding Proteins - metabolism | Signal Transduction - physiology | Cell Shape - physiology | Neoplasms - pathology | rac1 GTP-Binding Protein - metabolism | Gels - pharmacology | rac1 GTP-Binding Protein - genetics | Physiological aspects | Cellular signal transduction | Motility | Research | Cells | Cancer cells | Signal transduction | Oncology | Genetics | Substrates | Cell adhesion & migration | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2016, Volume 291, Issue 13, pp. 6912 - 6922
The activity of Rac in leukocytes is essential for immunity. However, its role in NK cell-mediated anti-microbial signaling remains unclear. In this study, we... 
IMMUNITY | Cellular signaling | Src | BIOCHEMISTRY & MOLECULAR BIOLOGY | SIGNALS | RECEPTOR | adhesion | Rac (Rac GTPase) | PHOSPHOINOSITIDE 3-KINASE | PLC-GAMMA | fungi | Cryptococcus | natural killer cells (NK cells) | phosphatidylinositide 3-kinase (PI 3-kinase) | PROTEINS | SMALL GTPASES | POLARIZATION | T-CELLS | LYMPHOCYTES | RNA, Small Interfering - genetics | Cryptococcus neoformans - physiology | Humans | Class Ia Phosphatidylinositol 3-Kinase - immunology | Pyrones - pharmacology | Quinolines - pharmacology | rac GTP-Binding Proteins - antagonists & inhibitors | rac1 GTP-Binding Protein - immunology | rac GTP-Binding Proteins - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Killer Cells, Natural - immunology | Phosphorylation - drug effects | Class Ia Phosphatidylinositol 3-Kinase - genetics | Killer Cells, Natural - microbiology | Mitogen-Activated Protein Kinase 3 - immunology | Mitogen-Activated Protein Kinase 1 - immunology | Mitogen-Activated Protein Kinase 3 - genetics | Signal Transduction | Gene Expression Regulation | rac GTP-Binding Proteins - immunology | src-Family Kinases - immunology | Host-Pathogen Interactions | rac1 GTP-Binding Protein - antagonists & inhibitors | Cell Line, Tumor | Killer Cells, Natural - drug effects | Primary Cell Culture | src-Family Kinases - genetics | Cytotoxicity, Immunologic | RNA, Small Interfering - metabolism | rac1 GTP-Binding Protein - genetics | Index Medicus | Immunology
Journal Article
Journal Article