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Nucleic Acids Research, ISSN 0305-1048, 04/2019, Volume 47, Issue 7, pp. 3550 - 3567
Abstract Activation of the checkpoint protein Tel1 requires the Mre11-Rad50-Xrs2 (MRX) complex, which recruits Tel1 at DNA double-strand breaks (DSBs) through... 
REPAIR | MRE11 | PROTEIN | MRE11/RAD50 | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA END-RESECTION | DOUBLE-STRAND BREAKS | CHECKPOINT RESPONSE | RAD50 HOOK | SAE2 | DAMAGE | Genome Integrity, Repair and
Journal Article
Molecular Cell, ISSN 1097-2765, 07/2017, Volume 67, Issue 2, pp. 334 - 347.e5
Journal Article
Journal Article
Cell, ISSN 0092-8674, 04/2011, Volume 145, Issue 1, pp. 54 - 66
Journal Article
Journal Article
by Chen, C and Wang, Y and Mei, J.F and Li, S.S and Xu, H.X and Xiong, H.P and Wang, X.H and He, X
Neoplasma, ISSN 0028-2685, 2018, Volume 65, Issue 1, pp. 75 - 80
Radiotherapy resistance remains the major factor limiting the radiotherapy efficacy in colorectal cancer. The Mrell-RAD50-Nbsl (MRN) complex is known to play a... 
DSB repair | RAD50 | Radiosensitivity | Colorectal cancer | colorectal cancer | MRE11/RAD50/NBS1 COMPLEX | MRE11 | PROTEIN | radiosensitivity | DOUBLE-STRAND BREAKS | IDENTIFICATION | REPAIR | RADIOSENSITIZATION | ONCOLOGY | NBS1 | EXPRESSION | CARCINOMA
Journal Article
Cell Reports, ISSN 2211-1247, 11/2018, Volume 25, Issue 7, pp. 1681 - 1692.e4
The yeast Mre11-Rad50-Xrs2 (MRX) complex has structural, signaling, and catalytic functions in the response to DNA damage. Xrs2, the eukaryotic-specific... 
Xrs2 | Rad50 | Tel1 | genome stability | Mre11 | DNA replication | DNA repair | SISTER-CHROMATID COHESION | MRE11 COMPLEX | GROSS CHROMOSOMAL REARRANGEMENTS | CRYSTAL-STRUCTURE | MRE11-RAD50-XRS2 COMPLEX | DOUBLE-STRAND BREAK | RAD50 HOOK DOMAIN | SACCHAROMYCES-CEREVISIAE | MITOTIC RECOMBINATION | MEIOTIC RECOMBINATION | CELL BIOLOGY
Journal Article
Cytokine, ISSN 1043-4666, 05/2016, Volume 81, pp. 1 - 9
IL-5 is a Th2 cytokine which activates eosinophils and is suggested to have an atheroprotective role. Genetic variants in the locus have been associated with... 
Intima-media thickness | Genetics | IL-5 | RAD50 | Subclinical atherosclerosis | Eosinophil count | IMMUNITY | MYOCARDIAL-INFARCTION | VARIANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUSCEPTIBILITY | RECEPTOR | IMMUNOLOGY | IDENTIFICATION | CELL BIOLOGY | INFLAMMATION | ARCHITECTURE | COMMON | Eosinophils - metabolism | Plaque, Atherosclerotic - genetics | Humans | Middle Aged | DNA Repair Enzymes - genetics | Genetic Loci - genetics | Male | Interleukin-5 - genetics | Coronary Artery Disease - blood | Female | Leukocyte Count | Plaque, Atherosclerotic - blood | Chromosomes, Human, Pair 5 - genetics | Genetics, Population | Gene Expression | Genetic Predisposition to Disease - genetics | Carotid Intima-Media Thickness | Europe | Risk Factors | Linear Models | DNA-Binding Proteins - genetics | Interleukin-5 - blood | Coronary Artery Disease - genetics | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Chromosomes, Human, Pair 14 - genetics | Genetic aspects | Interleukins | Cardiovascular diseases | Risk factors | Index Medicus | IMT-Bifmean, mean of IMT measures in the carotid bifurcation | IMTmean-max, mean of the maximum IMT measures along the entire carotid tree | IMT-CCmax, max of IMT measures in the common carotid | IMT-CCmean, mean of IMT measures in the common carotid | IMT-Bifmax, max of IMT measures in the carotid bifurcation | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2014, Volume 53, Issue 1, pp. 7 - 18
Journal Article