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2008, 1. Aufl., Cancer drug discovery and development series, ISBN 1934115290, xxi, 419
Book
PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, pp. e0178204 - e0178204
This study was designed to identify potential radiosensitizing (RS) agents for combined radio-and chemotherapy in a murine model of human lung carcinoma, and... 
THERAPY | INHIBITION | MRI | MULTIDISCIPLINARY SCIENCES | TUMOR RESPONSE | CHEMORADIOTHERAPY | MECHANISMS | CANCER | RADIATION | CHEMOTHERAPY | MOLECULES | Carcinoma, Non-Small-Cell Lung - pathology | A549 Cells | Carcinoma, Non-Small-Cell Lung - radiotherapy | Cell Survival - drug effects | Lung Neoplasms - drug therapy | Neoplasm Transplantation | Triterpenes - pharmacology | Humans | Radiation-Sensitizing Agents - pharmacology | Lung Neoplasms - radiotherapy | Lung Neoplasms - pathology | Male | Random Allocation | Cell Survival - radiation effects | Chemoradiotherapy | Feasibility Studies | Animals | Mice, Nude | Diffusion Magnetic Resonance Imaging | Lung Neoplasms - diagnostic imaging | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Carcinoma, Non-Small-Cell Lung - drug therapy | Drug Screening Assays, Antitumor | Usage | Care and treatment | Chemotherapy | Lung cancer | Patient outcomes | Cancer cells | Diagnosis | Research | Radiotherapy | Cancer | Animal models | Nuclear magnetic resonance--NMR | Genomics | Lung | Radioresistance | Cancer therapies | Ionizing radiation | Radiosensitization | Diffusion coefficient | Drug dosages | Correlation coefficient | Small cell lung carcinoma | Feasibility studies | Non-small cell lung carcinoma | I.R. radiation | Lung carcinoma | Radiation therapy | Gene expression | Medicine | Magnetic resonance imaging | Connectivity | Resonance | Tumors | Apoptosis | Index Medicus | Nuclear magnetic resonance | NMR
Journal Article
BMC Cancer, ISSN 1471-2407, 01/2015, Volume 15, Issue 1, pp. 21 - 21
Journal Article
Journal Article
GENES & DEVELOPMENT, ISSN 0890-9369, 06/2004, Volume 18, Issue 11, pp. 1331 - 1344
S(N)1-type alkylating agents represent an important class of chemotherapeutics, but the molecular mechanisms underlying their cytotoxicity are unknown. Thus,... 
G check point | PROTEIN-KINASE | NITRO-N-NITROSOGUANIDINE | DNA damage signaling | mismatch repair | DEVELOPMENTAL BIOLOGY | cell cycle arrest | methylating agents | STRAND BREAKS | DNA-DAMAGE CHECKPOINT | REPLICATION | ATM/ATR | CELL-CYCLE CHECKPOINT | GENETICS & HEREDITY | S-PHASE | RECENT PROGRESS | RADIOSENSITIZING AGENT | ALKYLATION DAMAGE
Journal Article
Current Colorectal Cancer Reports, ISSN 1556-3790, 8/2016, Volume 12, Issue 4, pp. 189 - 200
Over the past several decades, the management of localized rectal cancer has evolved from surgery alone as the definitive treatment to incorporating both... 
Targeted therapies | Medicine & Public Health | Rectal cancer | Colorectal Surgery | Radiosensitizing therapy | Oncology | Chemoradiotherapy | Proctology | Care and treatment | Chemotherapy | Epidermal growth factor | Colorectal cancer | Radiation | Radiotherapy | Vascular endothelial growth factor | Sugars | Cancer | Fluorouracil | Monosaccharides
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 3/2012, Volume 55, Issue 5, pp. 2437 - 2451
This report describes the design and application of several distinct gold-containing indoles as anti-cancer agents. When used individually, all gold-bearing... 
Gold | apoptosis | indoles | chemotherapy | radiosensitizing agents
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 03/2011, Volume 29, Issue 7, pp. 23 - 23
Conference Proceeding
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2017, Volume 138, pp. 979 - 992
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 04/2001, Volume 19, Issue 8, pp. 2319 - 2333
Journal Article
Cancer Cell, ISSN 1535-6108, 2007, Volume 11, Issue 2, pp. 175 - 189
In response to DNA damage, eukaryotic cells activate ATM-Chk2 and/or ATR-Chk1 to arrest the cell cycle and initiate DNA repair. We show that, in the absence of... 
SIGNALING | CANCER-CELLS | ONCOLOGY | 7-HYDROXYSTAUROSPORINE UCN-01 | MITOTIC CATASTROPHE | SECKEL-SYNDROME | MAPKAP KINASE-2 | NUCLEAR EXPORT | INDUCED CYTOTOXICITY | 14-3-3 PROTEIN-BINDING | RADIOSENSITIZING AGENT | PHOSPHORYLATION SITES | Protein Kinases - genetics | Antibiotics, Antineoplastic - pharmacology | Humans | DNA Repair - radiation effects | Staurosporine - analogs & derivatives | Bone Neoplasms - pathology | G2 Phase - drug effects | Bone Neoplasms - metabolism | DNA-Binding Proteins - metabolism | Neoplasms, Experimental - pathology | Tumor Suppressor Protein p53 - physiology | Ultraviolet Rays | Antineoplastic Agents - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | cdc25 Phosphatases - metabolism | Osteosarcoma - metabolism | Protein-Serine-Threonine Kinases - metabolism | DNA Damage - drug effects | DNA Repair - drug effects | Tumor Suppressor Proteins - metabolism | Mitosis - radiation effects | G2 Phase - radiation effects | Signal Transduction | Cell Survival | Cell Cycle Proteins - metabolism | Cells, Cultured | Cell Division - radiation effects | Intracellular Signaling Peptides and Proteins | Protein Kinase C - antagonists & inhibitors | Ataxia Telangiectasia Mutated Proteins | Cisplatin - pharmacology | Cell Division - drug effects | Mice, Knockout | Phosphorylation - radiation effects | S Phase - radiation effects | Animals | Mitosis - drug effects | Mice, Nude | Protein Kinases - physiology | Mice | S Phase - drug effects | Neoplasms, Experimental - metabolism | DNA Damage - radiation effects | Doxorubicin - pharmacology | Osteosarcoma - pathology | Staurosporine - pharmacology | DNA | Index Medicus
Journal Article