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JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 09/2000, Volume 275, Issue 39, pp. 29980 - 29985
Microtubule-damaging agents arrest cells at G(2)/M and induce apoptosis in association with phosphorylation of the anti-apoptotic proteins Bcl-2 and Bcl-X-L.... 
RAF-1/BCL-2 PHOSPHORYLATION | PROTEIN-KINASE PATHWAY | APOPTOSIS | ACTIVATION | CANCER CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | RAF-1 | DEATH
Journal Article
Cancer Research, ISSN 0008-5472, 05/2012, Volume 72, Issue 10, pp. 2457 - 2467
Journal Article
Biochimica et Biophysica Acta. C, Molecular Cell Research, ISSN 0167-4889, 2015, Volume 1853, Issue 7, pp. 1606 - 1614
Rotenone (ROT) is a widely used inhibitor of complex I (CI), the first complex of the mitochondrial oxidative phosphorylation (OXPHOS) system. However,... 
murine myotube formation | ROCK2 | Raf-1 | Rotenone
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 04/2010, Volume 23, Issue 2, pp. 190 - 200
Summary BRAFV600E/K is a frequent mutationally active tumor‐specific kinase in melanomas that is currently targeted for therapy by the specific inhibitor... 
drug response | cell migration | ERK pathway | serum markers | melanoma | BRAF | RAF1 | Drug response | Melanoma | Serum markers | Cell migration | CANCER | CELL BIOLOGY | DERMATOLOGY | ONCOLOGY | KIT | RAF-1 | REVEALS | Original
Journal Article
国际眼科杂志:英文版, ISSN 2222-3959, 2016, Volume 9, Issue 10, pp. 1371 - 1375
AIM: To investigate the expression of the v-raf-1murine leukemia viral oncogene homolog 1(Raf-1) and its role in the innate immune response of human corneal... 
Innate immune | Human corneal epithelial cells | Dectin-1/Raf-1 signal pathway | Aspergillus fumigatus | innate immune | DEFENSE | RAF-1 KINASE | ACTIVATION | human corneal epithelial cells | TYROSINE PHOSPHORYLATION | PATHWAY | OPHTHALMOLOGY | Aspergillus fumigates
Journal Article
Toxicology, ISSN 0300-483X, 2008, Volume 250, Issue 1, pp. 55 - 61
Abstract Protein kinase C (PKC) family of serine/threonine protein kinases is sensitive signaling transducers in response to lead acetate (Pb) that could... 
Emergency | Lung cancer cells | Lead acetate | PKCα | Mutation frequency | Phospho-Raf-1 S338 | Phospho-Raf-1 | mutation frequency | PHOSPHORYLATION | PKC alpha | PKC-ALPHA | phospho-Raf-1(S338) | INORGANIC LEAD | lead acetate | NUCLEOTIDE EXCISION-REPAIR | ISOZYMES | INHIBITION | HUMAN ASTROCYTOMA-CELLS | PATHWAY | RAF-1 | PHARMACOLOGY & PHARMACY | TOXICOLOGY | DIFFERENTIATION | lung cancer cells
Journal Article
Cell Cycle, ISSN 1538-4101, 12/2018, Volume 17, Issue 24, pp. 2666 - 2683
Multiple myeloma (MM) is a cancer that occurs in plasma cells, which fall under the category of white blood cells that are in charge of antibody production.... 
multiple myeloma | proliferation | invasion | MAPK/ERK signaling pathway | MicroRNA-497 | migration | Raf-1
Journal Article
MOLECULAR BIOLOGY OF THE CELL, ISSN 1059-1524, 04/2019, Volume 30, Issue 9, pp. 1108 - 1117
HRAS, NRAS, and KRAS isoforms are almost identical proteins that are ubiquitously expressed and activate a common set of effectors. In vivo studies have... 
ONCOGENIC K-RAS | REPLACEMENT | CELLS | H-RAS | N-RAS | PATHWAY | ACTIVATE RAF-1 | PROLIFERATION | MUTATIONS | CANCER | CELL BIOLOGY
Journal Article
SCIENCE, ISSN 0036-8075, 12/2004, Volume 306, Issue 5705, pp. 2267 - 2270
The ablation of the protein kinase Raf-1 renders cells hypersensitive to apoptosis despite normal regulation of extracellular signal-regulated kinases, which... 
C-RAF-1 GENE | PROTEIN INTERACTIONS | ACTIVATION | RAS | MULTIDISCIPLINARY SCIENCES | HIPPO | PROLIFERATION | CELL-CYCLE EXIT | DROSOPHILA | PROMOTES APOPTOSIS | SALVADOR
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 11/2001, Volume 21, Issue 21, pp. 7207 - 7217
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
MEK1 protein | Raf kinase inhibitor protein | Raf-1 protein | IKK protein | Cell Growth and Development
Journal Article
by Yang, LF and Tang, L and Dai, F and Meng, GL and Yin, RT and Xu, XL and Yao, WJ
TOXICOLOGY, ISSN 0300-483X, 08/2017, Volume 389, pp. 74 - 84
Both RhoA/ROCK and Raf-1/CK2 pathway play essential roles in cell proliferation, apoptosis, differentiation, and multiple other common cellular functions. We... 
Vimentin | ACTIVATION | PHOSPHORYLATION | Rho signaling | KINASE | Raf-1 | PLASMA-MEMBRANE | ACTIN STRESS FIBERS | Tumor necrosis factor-alpha | PATHWAY | RAF | PHARMACOLOGY & PHARMACY | TOXICOLOGY | DYSFUNCTION | RHO-GTPASES | INTERMEDIATE-FILAMENTS | Apoptosis
Journal Article
Cancer Research, ISSN 0008-5472, 08/1998, Volume 58, Issue 15, pp. 3331 - 3338
The oncogenic protein Bcl-2 functions as a potent inhibitor of programmed cell death. This survival activity has been shown in some settings to be influenced... 
BCL-2 PROTEIN | MECHANISM | ONCOLOGY | MITOCHONDRIA | KINASE | RAF-1 | DEATH | TAXOL-INDUCED APOPTOSIS | C-RAF-1 | EXPRESSION
Journal Article
Molecular Cell, ISSN 1097-2765, 02/2019, Volume 73, Issue 4, pp. 830 - 844.e12
Proximity-dependent biotin labeling (BioID) may identify new targets for cancers driven by difficult-to-drug oncogenes such as Ras. Therefore, BioID was used... 
BioID | CRISPR | proteomics | Ras | MAPKAP1 | mTOR | cancer | ACTIVATION | INHIBITION | ALIGNMENT | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | NETWORKS | C-RAF-1 | IDENTIFICATION | PROTEINS | PHOSPHOINOSITIDE 3-KINASE | CELL BIOLOGY | Proteins | Stem cell research | Biotin | Stem cells | Protein binding
Journal Article
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