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Nature, ISSN 0028-0836, 04/2018, Volume 556, Issue 7699, pp. 64 - 69
Nutrients, such as amino acids and glucose, signal through the Rag GTPases to activate mTORC1. The GATOR1 protein complex-comprising DEPDC5, NPRL2 and... 
MTORC1 | ACTIVATION | RAG GTPASES | RHEB | PATHWAY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | TUMOR-SUPPRESSOR | TSC2 GAP ACTIVITY | CELL-GROWTH | GTP-BINDING PROTEINS | Humans | Protein Multimerization | Monomeric GTP-Binding Proteins - ultrastructure | Repressor Proteins - ultrastructure | Guanosine Triphosphate - metabolism | GTPase-Activating Proteins - metabolism | Protein Subunits - metabolism | Multiprotein Complexes - antagonists & inhibitors | Multiprotein Complexes - metabolism | Tumor Suppressor Proteins - chemistry | Protein Domains | Repressor Proteins - metabolism | Repressor Proteins - chemistry | Tumor Suppressor Proteins - metabolism | Tumor Suppressor Proteins - ultrastructure | GTPase-Activating Proteins - antagonists & inhibitors | Models, Molecular | Mechanistic Target of Rapamycin Complex 1 - antagonists & inhibitors | Amino Acids - deficiency | GTPase-Activating Proteins - chemistry | Mechanistic Target of Rapamycin Complex 1 - metabolism | Cryoelectron Microscopy | Hydrolysis | Multiprotein Complexes - ultrastructure | Multiprotein Complexes - chemistry | Monomeric GTP-Binding Proteins - metabolism | Monomeric GTP-Binding Proteins - chemistry | Protein Binding | Protein Subunits - chemistry | GTPase-Activating Proteins - ultrastructure | GTP | Starvation | Desensitization | Architecture | Amino acids | Homology | Electron microscopy | Kinases | Substrates | Proteins | Signal transduction | Signaling | Nutrient loss | GTPase-activating protein | Microscopy | Nutrients | Guanosinetriphosphatase | Crystal structure | Index Medicus
Journal Article
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2011, Volume 286, Issue 37, pp. 32651 - 32660
Journal Article
Journal Article
Autophagy, ISSN 1554-8627, 06/2018, Volume 14, Issue 6, pp. 1105 - 1106
Target of rapamycin complex 1 (TORC1) is an evolutionarily conserved protein kinase complex, whose activation in response to nutrients suppresses autophagy. In... 
TORC1 | autophagy | Ragulator | proliferation | TOR | GATOR1 | Rag GTPase | CELL BIOLOGY | Index Medicus
Journal Article
16.