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The Journal of Immunology, ISSN 0022-1767, 06/2005, Volume 174, Issue 11, pp. 6686 - 6691
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2016, Volume 22, Issue 8, pp. 933 - 939
Individuals who have mutations in the breast-cancer-susceptibility gene BRCA1 (hereafter referred to as BRCA1-mutation carriers) frequently undergo... 
BRCA2 MUTATION CARRIERS | MEDICINE, RESEARCH & EXPERIMENTAL | TUMOR-DEVELOPMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | OVARIAN-CANCER | CELL BIOLOGY | RISK-REDUCING SURGERY | STEM-CELL | MICE | DIFFERENTIAL EXPRESSION ANALYSIS | GLAND | MAMMARY EPITHELIAL-CELLS | Immunohistochemistry | Neoplasm Transplantation | RANK Ligand - metabolism | Humans | Molecular Targeted Therapy | Prophylactic Mastectomy | Stem Cells - metabolism | Breast - metabolism | Breast Neoplasms - metabolism | Denosumab - therapeutic use | Flow Cytometry | Organoids - metabolism | Female | Receptor Activator of Nuclear Factor-kappa B - metabolism | Disease Models, Animal | Carcinogenesis - genetics | Bone Density Conservation Agents - therapeutic use | Reverse Transcriptase Polymerase Chain Reaction | Bone Density Conservation Agents - pharmacology | Breast Neoplasms - prevention & control | Carcinogenesis - drug effects | Xenograft Model Antitumor Assays | BRCA1 Protein - genetics | Animals | Breast Neoplasms - genetics | RANK Ligand - antagonists & inhibitors | Breast - drug effects | DNA Repair | Organoids - drug effects | Pilocarpine - analogs & derivatives | Stem Cells - drug effects | Heterozygote | Cell Proliferation - drug effects | Mice | Mutation | Denosumab - pharmacology | Tumor Suppressor Proteins | Care and treatment | Cytokines | BRCA mutations | Development and progression | Breast cancer | Genetic aspects | Health aspects | Ligands | Genes
Journal Article
Journal of Clinical Periodontology, ISSN 0303-6979, 05/2009, Volume 36, Issue 5, pp. 396 - 403
Aim: T regulatory (Treg) cells have been detected in periodontitis lesions, and forkhead box P3 (Foxp3) expression has been negatively correlated to receptor... 
regulatory T cells | CTLA‐4 | RANKL | periodontitis | Treg | CD25 | Foxp3 | IL‐17 | RORC2 | Periodontitis | IL-17 | CTLA-4 | Regulatory T cells | CYTOKINES | TGF-BETA | SUBPOPULATIONS | MATRIX METALLOPROTEINASE-13 | DENDRITIC CELLS | LYMPHOCYTE | INFLAMMATION | DENTISTRY, ORAL SURGERY & MEDICINE | REGULATORY T-CELLS | PARADIGM | Forkhead Transcription Factors - immunology | GATA3 Transcription Factor - immunology | Humans | Interleukin-17 - analysis | Interleukin-17 - immunology | DNA-Binding Proteins - analysis | T-Box Domain Proteins - immunology | Th2 Cells - immunology | Th1 Cells - immunology | Lymphotoxin-alpha - immunology | T-Lymphocytes, Regulatory - immunology | RANK Ligand - immunology | Transforming Growth Factor beta1 - immunology | T-Lymphocytes, Helper-Inducer - immunology | Receptors, Retinoic Acid - immunology | Receptors, Retinoic Acid - analysis | Chronic Periodontitis - immunology | T-Box Domain Proteins - analysis | GATA3 Transcription Factor - analysis | Transforming Growth Factor beta1 - analysis | Interleukin-10 - analysis | Receptors, Thyroid Hormone - immunology | Cytokines - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 | Interleukin-1beta - analysis | DNA-Binding Proteins - immunology | Gene Expression Regulation - genetics | Interleukin-1beta - immunology | RANK Ligand - analysis | Reverse Transcriptase Polymerase Chain Reaction | Disease Progression | Alveolar Bone Loss - immunology | Interferon-gamma - analysis | Receptors, Thyroid Hormone - analysis | Lymphotoxin-alpha - analysis | Down-Regulation - immunology | Interferon-gamma - immunology | Forkhead Transcription Factors - analysis | Interleukin-10 - immunology
Journal Article
Journal Article
Nature, ISSN 0028-0836, 11/2010, Volume 468, Issue 7320, pp. 103 - 107
RANK ligand (RANKL), a TNF-related molecule, is essential for osteoclast formation, function and survival through interaction with its receptor RANK(1,2).... 
CELL FUNCTION | OSTEOPROTEGERIN-LIGAND | MULTIDISCIPLINARY SCIENCES | MEDROXYPROGESTERONE ACETATE | RECEPTOR | HORMONE REPLACEMENT THERAPY | HUMAN BREAST-TUMORS | OSTEOCLAST DIFFERENTIATION | EXPRESSION | GLAND DEVELOPMENT | TRANSGENIC MICE | Epithelial Cells - metabolism | RANK Ligand - metabolism | Progesterone - administration & dosage | Epithelial Cells - drug effects | Humans | Progestins - adverse effects | Cell Transformation, Neoplastic - chemically induced | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | Lung Neoplasms - secondary | Mammary Neoplasms, Experimental - pathology | Medroxyprogesterone Acetate - adverse effects | Female | Precancerous Conditions - pathology | Receptor Activator of Nuclear Factor-kappa B - metabolism | Disease Models, Animal | 9,10-Dimethyl-1,2-benzanthracene - administration & dosage | Neoplasm Invasiveness | Mice, Inbred C57BL | Epithelial Cells - pathology | Mice, Transgenic | Progesterone - adverse effects | Mammary Neoplasms, Experimental - chemically induced | RANK Ligand - genetics | Animals | RANK Ligand - antagonists & inhibitors | Breast Neoplasms - pathology | Progestins - administration & dosage | Receptor Activator of Nuclear Factor-kappa B - genetics | Cell Proliferation - drug effects | Medroxyprogesterone Acetate - administration & dosage | Mice | Cell Transformation, Neoplastic - drug effects | Precancerous Conditions - prevention & control | Cell Transformation, Neoplastic - pathology | Mammary Tumor Virus, Mouse - genetics | Mammary Tumor Virus, Mouse - physiology | 9,10-Dimethyl-1,2-benzanthracene - adverse effects | Immunohistochemistry | Care and treatment | Usage | Physiological aspects | Breast cancer | Genetic aspects | Research | Progesterone | Tumor proteins | Health aspects | Risk factors | Proteins | Hormone replacement therapy | Rodents | Apoptosis | Index Medicus
Journal Article
Journal Article
Journal of Clinical Periodontology, ISSN 0303-6979, 03/2012, Volume 39, Issue 3, pp. 239 - 248
Background and Objectives The receptor activator of NF‐κB ligand‐osteoprotegerin (RANKL‐OPG) bi‐molecular system is the “bottle‐neck” regulator of... 
gingival crevicular fluid | receptor activator of NF‐κB ligand | diagnostics | receptor activator of NF‐κB ligand/osteoprotegerin ratio | osteoprotegerin | periodontal disease | receptor activator of NF-ÎB ligand/osteoprotegerin ratio | receptor activator of NF-ÎB ligand | receptor activator of NF-?B ligand | DIFFERENTIAL EXPRESSION | osteoprotegerin ratio | NECROSIS-FACTOR-ALPHA | TRANSCRIPTION FACTOR NFATC1 | MESSENGER-RNA | DENTISTRY, ORAL SURGERY & MEDICINE | OSTEOPROTEGERIN LIGAND | RECEPTOR ACTIVATOR | OSTEOCLAST DIFFERENTIATION | KAPPA-B LIGAND | ALVEOLAR BONE DESTRUCTION | Alveolar Bone Loss - metabolism | Biomarkers - metabolism | Lymphocytes - metabolism | Alveolar Bone Loss - therapy | RANK Ligand - metabolism | Humans | Periodontitis - therapy | Diabetes Mellitus - metabolism | Periodontitis - blood | Gingival Crevicular Fluid - chemistry | Biomarkers - blood | Saliva - chemistry | Periodontal Ligament - metabolism | Periodontitis - metabolism | Dental Plaque - microbiology | Smoking - metabolism | RANK Ligand - blood | Animals | Gingiva - chemistry | Osteoporosis - metabolism | Osteoprotegerin - blood | Osteoprotegerin - metabolism | Osteoblasts - metabolism | Alveolar Bone Loss - blood | Oral hygiene | Immune system | Diabetes mellitus | biomarkers | Blood | Osteoprotegerin | Bone resorption | Osteoclastogenesis | Periodontal diseases | NF- Kappa B protein | Molecular modelling | Periodontitis | Gingiva | TRANCE protein | Saliva | Smoking
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2003, Volume 170, Issue 4, pp. 1797 - 1805
Members of the TNF superfamily have been shown to be instrumental in enhancing cell-mediated immune responses, primarily through their interactions with... 
HELP | PLASMA VIREMIA | TUMOR-NECROSIS-FACTOR | VIRUS-INFECTION | HIV-INFECTION | INTERFERON-GAMMA | TRANCE | IMMUNOLOGY | MHC CLASS-II | DISEASE PROGRESSION | CUTTING EDGE | CD40 Ligand - physiology | Receptor Activator of Nuclear Factor-kappa B | Monocytes - cytology | Coculture Techniques | Dendritic Cells - immunology | Humans | Glycoproteins - metabolism | Culture Media, Conditioned - pharmacology | Monocytes - metabolism | NF-kappa B - metabolism | RANK Ligand | Monocytes - immunology | Lymphocyte Depletion | Interleukin-15 - biosynthesis | Osteoprotegerin | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | Membrane Glycoproteins - physiology | Cell Division - immunology | Leukocytes, Mononuclear - immunology | Epitopes, T-Lymphocyte - immunology | Dendritic Cells - metabolism | Interleukin-12 - biosynthesis | Carrier Proteins - physiology | T-Lymphocytes, Cytotoxic - immunology | CD4-Positive T-Lymphocytes - cytology | HIV Infections - virology | Cells, Cultured | Herpesvirus 4, Human - immunology | Immunophenotyping | Cell Differentiation - immunology | HIV-1 - immunology | Receptors, Tumor Necrosis Factor | CD8-Positive T-Lymphocytes - virology | Tumor Necrosis Factor-alpha - physiology | Immunologic Memory | Interleukin-10 - biosynthesis | Leukocytes, Mononuclear - cytology | Dendritic Cells - cytology | CD8-Positive T-Lymphocytes - immunology | T-Lymphocytes, Cytotoxic - cytology | Drug Combinations | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article
Journal Article