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Journal Article
Circulation research, ISSN 1524-4571, 2018, Volume 122, Issue 3, pp. 489 - 505
The mTOR (mechanistic target of rapamycin) is a master regulator of several crucial cellular processes, including protein synthesis, cellular growth,... 
Heart | Mice | Cardiovascular diseases | Autophagy | Hypertrophy | MAMMALIAN TARGET | CARDIAC & CARDIOVASCULAR SYSTEMS | autophagy | ACTIVATED PROTEIN-KINASE | RAG GTPASES | hypertrophy | MYOCARDIAL-ISCHEMIA | cardiovascular diseases | DIET-INDUCED OBESITY | mice | heart | ISCHEMIA-REPERFUSION INJURY | TERM CALORIC RESTRICTION | CARDIAC-HYPERTROPHY | PERIPHERAL VASCULAR DISEASE | PROMOTES HEART-FAILURE | TUBEROUS SCLEROSIS | HEMATOLOGY | Adaptation, Physiological | Mechanistic Target of Rapamycin Complex 1 - physiology | Mechanistic Target of Rapamycin Complex 2 - physiology | Protein Biosynthesis | Humans | Stress, Mechanical | Hypoxia - metabolism | Organelle Biogenesis | Mammals - physiology | TOR Serine-Threonine Kinases - physiology | Cardiovascular Physiological Phenomena | Signal Transduction | Cell Survival | Heart Diseases - physiopathology | Mechanistic Target of Rapamycin Complex 1 - deficiency | Models, Cardiovascular | Mechanistic Target of Rapamycin Complex 2 - deficiency | Gene Expression Regulation | Cardiomegaly - physiopathology | Lipid Metabolism | Mechanistic Target of Rapamycin Complex 1 - antagonists & inhibitors | Mitochondria - metabolism | Heart Diseases - enzymology | Animals | Energy Metabolism | Heart Diseases - drug therapy | Cell proliferation | Cardiovascular system | Heart failure | Care and treatment | Analysis | Cell metabolism | Physiological aspects | Protein biosynthesis | Rapamycin | Dosage and administration | Research | Cardiopulmonary system | mTOR signaling | mTORC2 | mTORC1 | reperfusion | ischemia
Journal Article
American journal of physiology. Heart and circulatory physiology, ISSN 1522-1539, 2018, Volume 314, Issue 4, pp. H693 - H703
An intact blood-brain barrier (BBB) limits entry of proinflammatory and neurotoxic blood-derived factors into the brain parenchyma. The BBB is damaged in... 
Mammalian/ mechanistic target of rapamycin | Brain endothelium | Cerebrovasculature | Rapamycin | Blood-brain barrier | blood-brain barrier | MAMMALIAN TARGET | LIFE-SPAN | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | brain endothelium | cerebrovasculature | RAPAMYCIN MTOR | INTEGRITY | JUNCTIONAL-ADHESION-MOLECULE | MITOCHONDRIAL DYSFUNCTION | PERIPHERAL VASCULAR DISEASE | MICE | IMMUNOSUPPRESSIVE DRUGS | mammalian/mechanistic target of rapamycin | NF-KAPPA-B | rapamycin | TOR Serine-Threonine Kinases - metabolism | Dementia, Vascular - drug therapy | Male | Cognition | Tight Junctions - enzymology | Alzheimer Disease - pathology | Behavior, Animal | TOR Serine-Threonine Kinases - antagonists & inhibitors | Matrix Metalloproteinase 9 - metabolism | Receptors, LDL - deficiency | Dementia, Vascular - pathology | Female | Alzheimer Disease - psychology | Tight Junction Proteins - metabolism | Disease Models, Animal | Tight Junctions - drug effects | Cell Line | Dementia, Vascular - psychology | Receptors, LDL - genetics | Mice, Inbred C57BL | Dementia, Vascular - enzymology | Alzheimer Disease - drug therapy | Alzheimer Disease - enzymology | Blood-Brain Barrier - drug effects | Sirolimus - pharmacology | Mechanistic Target of Rapamycin Complex 1 - metabolism | Mice, Knockout | Blood-Brain Barrier - pathology | Animals | Blood-Brain Barrier - enzymology | Protein Kinase Inhibitors - pharmacology | Tight Junctions - pathology | Physiological aspects | Models | Alzheimer's disease | Phosphotransferases | mammalian | mechanistic target of rapamycin
Journal Article
The journals of gerontology. Series A, Biological sciences and medical sciences, ISSN 1758-535X, 2016, Volume 71, Issue 7, pp. 841 - 849
Journal Article
Angiogenesis, ISSN 0969-6970, 7/2016, Volume 19, Issue 3, pp. 359 - 371
Journal Article
Journal Article