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2012, Methods in molecular biology, ISBN 1617794309, Volume 821
Web Resource
2012, Methods in molecular biology, ISBN 9781617794292, Volume 821., xiii, 464
Book
Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7606, pp. 272 - 276
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2010, Volume 285, Issue 17, pp. 13107 - 13120
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 497, Issue 7448, pp. 217 - 223
The mammalian target of rapamycin (mTOR), a phosphoinositide 3-kinase-related protein kinase, controls cell growth in response to nutrients and growth factors... 
MAMMALIAN TARGET | RAPTOR | BINDING PARTNER | RAG GTPASES | TOS MOTIF | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | PIK-RELATED KINASES | CELL-GROWTH | P70 S6 KINASE | RAPAMYCIN COMPLEX-1 | Adaptor Proteins, Signal Transducing - chemistry | Catalytic Domain - drug effects | TOR Serine-Threonine Kinases - metabolism | Pyridines - chemistry | Furans - pharmacology | Humans | Crystallography, X-Ray | Structure-Activity Relationship | Pyrimidines - chemistry | TOR Serine-Threonine Kinases - antagonists & inhibitors | Indoles - metabolism | Furans - chemistry | Adenosine Triphosphate - metabolism | Indoles - pharmacology | Tacrolimus Binding Protein 1A - pharmacology | Naphthyridines - chemistry | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Purines - metabolism | Purines - pharmacology | MTOR Associated Protein, LST8 Homolog | Tacrolimus Binding Protein 1A - chemistry | Models, Molecular | Magnesium - metabolism | Pyrimidines - pharmacology | Sirolimus - metabolism | Sirolimus - pharmacology | Magnesium - chemistry | Purines - chemistry | TOR Serine-Threonine Kinases - chemistry | Tacrolimus Binding Protein 1A - metabolism | Pyridines - pharmacology | Sirolimus - chemistry | Adaptor Proteins, Signal Transducing - metabolism | Adenosine Triphosphate - chemistry | Indoles - chemistry | Naphthyridines - pharmacology | Naphthyridines - metabolism | Protein Structure, Tertiary - drug effects | Proteins | Enzymes | Kinases | Crystal structure | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, pp. e35572 - e35572
While natural CD4(+)Foxp3(+) regulatory T (nT(REG)) cells have long been viewed as a stable and distinct lineage that is committed to suppressive functions in... 
CPG OLIGODEOXYNUCLEOTIDES | LEISHMANIA-MAJOR | TGF-BETA | T(H)17 LINEAGE | ROR-GAMMA-T | TRANSCRIPTION FACTOR FOXP3 | SUPPRESSIVE FUNCTION | BIOLOGY | IMMUNOLOGICAL SELF-TOLERANCE | CUTTING EDGE | TH17 CELLS | Forkhead Transcription Factors - immunology | Th1 Cells - pathology | T-Lymphocytes, Regulatory - metabolism | Gene Expression - drug effects | Interleukin-17 - immunology | Intestines - metabolism | Th1 Cells - immunology | Intestines - immunology | T-Lymphocytes, Regulatory - immunology | TOR Serine-Threonine Kinases - antagonists & inhibitors | Interleukin-2 - immunology | Intestines - parasitology | Immunosuppressive Agents - pharmacology | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Th17 Cells - pathology | CD4 Antigens - immunology | Promoter Regions, Genetic | Down-Regulation | Mice, Inbred C57BL | Inflammation - immunology | Forkhead Transcription Factors - genetics | Sirolimus - pharmacology | TOR Serine-Threonine Kinases - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | Inflammation - genetics | Th17 Cells - immunology | Lymphopenia - immunology | Mice | Lymphopenia - genetics | TOR protein | Transcription factors | Laboratories | Helper cells | Homeostasis | Effector cells | Lymphocytes T | Kinases | Immunity | Immunosuppressive agents | Thymus | Plasticity (functional) | Genotype & phenotype | Immunology | Interleukin 2 | Parasitic diseases | Lymphocytes | Rodents | Foxp3 protein | Inhibition | Growth factors | Departments | Immunoregulation | Organs | Pharmacology | Rapamycin | Inflammation | T cell receptors | Interleukin 17 | CD4 antigen | Medicine | Studies | Signaling | Index Medicus
Journal Article
Transplantation Proceedings, ISSN 0041-1345, 2008, Volume 40, Issue 10, pp. S5 - S8
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 12/2012, Volume 209, Issue 13, pp. 2441 - 2453
mTORC1 (mammalian target of rapamycin complex 1) controls transcriptional programs that determine CD8(+) cytolytic T cell (CTL) fate. In some cell systems,... 
MAMMALIAN TARGET | RAPAMYCIN | SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | EFFECTOR FUNCTIONS | L-SELECTIN | ACTIVATION | KINASE | RECEPTOR | DIFFERENTIATION | IMMUNOLOGY | LYMPHOCYTES | CD8-Positive T-Lymphocytes - cytology | TOR Serine-Threonine Kinases - metabolism | Multiprotein Complexes | Phosphatidylinositol 3-Kinases - metabolism | Aryl Hydrocarbon Receptor Nuclear Translocator - metabolism | Hypoxia-Inducible Factor 1 - metabolism | Cell Movement - physiology | Hypoxia-Inducible Factor 1 - genetics | Mechanistic Target of Rapamycin Complex 1 | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Mice, Mutant Strains | CD8-Positive T-Lymphocytes - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cell Differentiation - physiology | 3-Phosphoinositide-Dependent Protein Kinases | Protein-Serine-Threonine Kinases - metabolism | Receptors, Antigen, T-Cell - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Mice, Transgenic | Phosphatidylinositol 3-Kinases - genetics | Animals | Proteins - metabolism | Glucose - metabolism | Glycolysis | Interleukin-2 - pharmacology | Aryl Hydrocarbon Receptor Nuclear Translocator - genetics | Chemokines - metabolism | Mice | CD8-Positive T-Lymphocytes - immunology | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 09/2008, Volume 68, Issue 18, pp. 7409 - 7418
Journal Article
Journal Article