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Cellular and Molecular Life Sciences, ISSN 1420-682X, 10/2014, Volume 71, Issue 20, pp. 4027 - 4042
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 05/2019, Volume 234, Issue 5, pp. 5915 - 5925
Peritoneal fibrosis remains to be one of the most severe causes of failure in continuous peritoneal dialysis. The current study cultured peritoneal mesothelial... 
microRNA‐21 | peritoneal fibrosis | proliferation | JNK | apoptosis | fibrosis in peritoneal mesothelial cells | Sprouty‐1 | ERK | RAS–MAPK signaling pathway | microRNA-21 | Sprouty-1 | PHYSIOLOGY | DIFFERENTIAL EXPRESSION | MECHANISMS | CELL BIOLOGY | BIOMARKERS | RAS-MAPK signaling pathway | INHIBITION | GENES | MIR-21 | ras Proteins - genetics | Cell Proliferation | Signal Transduction | Peritoneum - enzymology | Peritoneal Fibrosis - genetics | Cells, Cultured | Peritoneal Fibrosis - enzymology | ras Proteins - metabolism | Male | Peritoneal Fibrosis - pathology | Peritoneal Fibrosis - chemically induced | Glucose | Nerve Tissue Proteins - genetics | Rats, Sprague-Dawley | Nerve Tissue Proteins - metabolism | Peritoneum - pathology | Animals | Peritoneal Dialysis | G1 Phase Cell Cycle Checkpoints | Mitogen-Activated Protein Kinases - genetics | MicroRNAs - genetics | Apoptosis | Disease Models, Animal | Mitogen-Activated Protein Kinases - metabolism | Cell culture | Flow cytometry | Animal models | Chymosin | Kinases | Peritoneal dialysis | Proteins | Signal transduction | Reporter gene | miRNA | Extracellular signal-regulated kinase | MAP kinase | Exposure | Ras protein | siRNA | Ribonucleic acid--RNA | Polymerase chain reaction | Signaling | Inhibitors | Protein kinase | Terminal protein | MicroRNAs | Fibrosis | Angiotensin | Dialysis | Viability | Peritoneum
Journal Article
Seminars in Cancer Biology, ISSN 1044-579X, 2017, Volume 48, pp. 27 - 35
Abstract Rational target therapy of cancer would benefit from the identification of new targets that can be easily inhibited by small molecules. An increasing... 
Hematology, Oncology and Palliative Medicine | Tumor microenvironment | PDPK1 | Myc | Ras/MAPK | PI3K/Akt | TARGETED THERAPY | 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE-1 | PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE | C-MYC | ONCOLOGY | CELL-MIGRATION | PROSTATE-CANCER | PLECKSTRIN HOMOLOGY DOMAIN | NF-KAPPA-B | MTOR COMPLEX | Protein kinases | Analysis | Cancer
Journal Article
Oncotarget, ISSN 1949-2553, 11/2017, Volume 8, Issue 55, pp. 94606 - 94618
Ataxin-1 (ATXN1) is a coregulator protein within which expansion of the polyglutamine tract causes spinocerebellar ataxia type 1, an autosomal dominant... 
Tumorigenesis | ATXN1 | EGFR-RAS-MAPK pathway | Cervical cancer | STEM-CELLS | ACTIVATION | CYCLIN D1 | SCA1 | DOWN-REGULATION | PROLIFERATION | cervical cancer | CELL BIOLOGY | GROWTH-FACTOR RECEPTOR | CARCINOMAS | tumorigenesis | TYPE-1 | ERK
Journal Article
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 12/2019, Volume 120, Issue 12, pp. 19245 - 19253
Colorectal cancer (CRC) is the leading cause of cancer death worldwide. Dysregulation of RAS/MAPK signaling axis is frequently found in CRC patients. The... 
RAS/MAPK signaling | microRNA | colorectal cancer | MicroRNA | Colorectal cancer | Cell proliferation | Pathogenesis | Colorectal carcinoma | MAP kinase | Disease control | Metastases | Signaling | Signal transduction | MicroRNAs | Biomarkers | miRNA | Cell migration | Apoptosis | Cancer
Journal Article
Child's Nervous System, ISSN 0256-7040, 6/2018, Volume 34, Issue 6, pp. 1247 - 1250
Apert syndrome is one of the most common craniosynostosis syndrome caused by mutation in genes encoding fibroblast growth factor receptor 2 (FGFR2).... 
Neurosciences | Apert syndrome | Medicine & Public Health | Neurosurgery | RASopathies | RAS/MAPK signaling pathway | Sturge-Weber syndrome | Fibronectin | Case studies | Cellular signal transduction | Diagnosis | Research
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 4/2012, Volume 107, Issue 2, pp. 343 - 349
Journal Article