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1. Full Text Autophagy in hypoxic ovary
by Yadav, Anil Kumar and Yadav, Pramod K and Chaudhary, Govind R and Tiwari, Meenakshi and Gupta, Anumegha and Sharma, Alka and Pandey, Ashutosh N and Pandey, Ajai K and Chaube, Shail K
Cellular and Molecular Life Sciences, ISSN 1420-682X, 9/2019, Volume 76, Issue 17, pp. 3311 - 3322
Oxygen deprivation affects human health by modulating system as well as cellular physiology. Hypoxia generates reactive oxygen species (ROS), causes oxidative... 
Life Sciences | Biomedicine, general | Biochemistry, general | Life Sciences, general | Beclin 1 | Granulosa cells | HIF-1α | Follicular atresia | Oocyte | Cell Biology | MAMMALIAN TARGET | ATRETIC FOLLICLES | OXIDATIVE STRESS | HIF-1 alpha | INDUCIBLE FACTOR-I | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEDIATED CLEAVAGE | CELL BIOLOGY | AIR-POLLUTION | GRANULOSA-CELL AUTOPHAGY | FEMALE RATS | OOCYTES | CORPUS-LUTEUM | Proteins | Medicine, Ayurvedic | Reproductive health | Women | Cell death | Zoology | Physiological aspects | Protein kinases | Health aspects | Cells | TOR protein | Health care | Oxidative stress | Protein kinase C | Menopause | Kinases | Autophagy | Necrosis | Reproduction | Pathways | Protein folding | Nutrients | Physiology | Deprivation | Reproductive systems | Oxygen | Cell survival | AMP | Mortality | Rapamycin | Mammals | Organelles | Depletion | Somatic cells | Hypoxia | Endoplasmic reticulum | Phagocytosis | Apoptosis
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2. Full Text Rodent models for human polycystic ovary syndrome
by Walters, Kirsty A and Allan, Charles M and Handelsman, David J
Biology of Reproduction, ISSN 0006-3363, 05/2012, Volume 86, Issue 5, p. 149, 1
Polycystic ovary syndrome (PCOS) is the most frequent female endocrine disorder, affecting 5%-10% of women, causing infertility due to dysfunctional follicular... 
Ovary | Animal models | Pcos | Follicular development | Fertility | HORMONE PULSE-GENERATOR | animal models | ESTROGEN-RECEPTOR GENE | fertility | PLASMINOGEN-ACTIVATOR INHIBITOR-1 | PERSISTENT ESTRUS | RAT MODEL | follicular development | ovary | PCOS | REPRODUCTIVE BIOLOGY | ELEVATED LUTEINIZING-HORMONE | FEMALE REPRODUCTIVE-TRACT | ZEALAND OBESE MOUSE | TESTOSTERONE PROPIONATE | EARLY-ANDROGEN SYNDROME | Polycystic Ovary Syndrome - metabolism | Receptors, Leptin - genetics | Humans | Rats | Receptors, Leptin - biosynthesis | Leptin - genetics | Estrogens - adverse effects | Polycystic Ovary Syndrome - chemically induced | Obesity - genetics | Obesity - metabolism | Plasminogen Activator Inhibitor 1 - biosynthesis | Aromatase Inhibitors - adverse effects | Progestins - antagonists & inhibitors | Animals | Polycystic Ovary Syndrome - genetics | Female | Leptin - biosynthesis | Mice | Androgens - adverse effects | Mutation | Plasminogen Activator Inhibitor 1 - genetics | Luteinizing Hormone - biosynthesis | Disease Models, Animal
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3. Full Text Postnatal Ovary Development in the Rat
: Morphologic Study and Correlation of Morphology to Neuroendocrine Parameters
by Picut, Catherine A and Dixon, Darlene and Simons, Michelle L and Stump, Donald G and Parker, George A and Remick, Amera K
Toxicologic Pathology, ISSN 0192-6233, 4/2015, Volume 43, Issue 3, pp. 343 - 353
Histopathologic examination of the immature ovary is a required end point on juvenile toxicity studies and female pubertal and thyroid function assays. To aid... 
ovary | Sprague-Dawley rats | endocrine disruptors | pubertal assay | female | postnatal development | reproduction | PATHOLOGY | PUBERTY | FEMALE RATS | FSH | TOXICOLOGY | MOUSE OVARY | ONSET | JUVENILE TOXICITY | Animals, Newborn | Ovary - anatomy & histology | Rats | Ovary - physiology | Gonadal Steroid Hormones - blood | Rats, Sprague-Dawley | Ovary - growth & development | Animals | Aging - physiology | Neurosecretory Systems - physiology | Estrus - physiology | Ovarian Follicle - physiology | Female | Neurosecretory Systems - growth & development
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4. Full Text Circadian clocks in the ovary
by Sellix, Michael T and Menaker, Michael
Trends in Endocrinology & Metabolism, ISSN 1043-2760, 2010, Volume 21, Issue 10, pp. 628 - 636
Clock gene expression has been observed in tissues of the hypothalamic–pituitary–gonadal (HPG) axis. Whereas the contribution of hypothalamic oscillators to... 
Endocrinology & Metabolism | LUTEINIZING-HORMONE SURGE | MESSENGER-RNA | RHYTHMS | SUPRACHIASMATIC NUCLEUS | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | PERIOD GENE | PROTEIN BMAL1 | NONCANONICAL E-BOX | GONADOTROPIN | REPRODUCTIVE-PERFORMANCE | Animals | Humans | Female | Ovary - physiology | Circadian Clocks - physiology | Ovulation - physiology | Ovary - metabolism | Gene expression | mouse | rat | rhythm | clock gene | ovulation | reproduction
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5. Full Text Myo‐inositol and D‐chiro‐inositol (40:1) reverse histological and functional features of polycystic ovary syndrome in a mouse model
by Bevilacqua, Arturo and Dragotto, Jessica and Giuliani, Alessandro and Bizzarri, Mariano
Journal of Cellular Physiology, ISSN 0021-9541, 06/2019, Volume 234, Issue 6, pp. 9387 - 9398
Mice exposed to continuous light undergo functional and histological changes that mimic those of human Polycystic Ovary Syndrome (PCOS). We herein induced the... 
Myo‐inositol | PCOS | continuous light model | D‐chiro‐inositol | D-chiro-inositol | Myo-inositol | INTERNATIONAL CONSENSUS CONFERENCE | PHYSIOLOGY | QUALITY | FOLLICULAR-FLUID | RATS | THECAL CELLS | CELL BIOLOGY | WOMEN | CONSTANT LIGHT | ANIMAL-MODELS | IVF | Stein-Leventhal syndrome | Inositol | Analysis | Polycystic ovary syndrome | Signs and symptoms | Phenotypes | Histology | Ovaries | Follicles | Recovery | Pregnancy | Thickness | Fertility | Morphology | Mice | Supplementation | Females | Continuity (mathematics) | Theca
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6. Full Text Bisphenol a exposure during adulthood causes augmentation of follicular atresia and luteal regression by Decreasing 17β-estradiol synthesis via downregulation of aromatase in rat ovary
by Lee, Seung Gee and Kim, Ji Young and Chung, Jin-Yong and Kim, Yoon-Jae and Park, Ji-Eun and Oh, Seunghoon and Yoon, Yong-Dal and Yoo, Ki Soo and Yoo, Young Hyun and Kim, Jong-Min
Environmental Health Perspectives, ISSN 0091-6765, 06/2013, Volume 121, Issue 6, pp. 663 - 669
BACKGROUND: Bisphenol A (BPA) has been detected in human body fluids, such as serum and ovarian follicular fluids. Several reports indicated that BPA exposure... 
Bisphenol a | Ovary | Aromatase | Luteal regression | 17β-estradiol | Steroidogenic acute regulatory protein | Follicular atresia | 17 beta-estradiol | NEONATAL EXPOSURE | aromatase | GRANULOSA-CELLS | UTERUS | STEROID-HORMONE PRODUCTION | ENVIRONMENTAL SCIENCES | ovary | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | PERINATAL EXPOSURE | FOLLICLES | BIOSYNTHESIS | ESTRADIOL | follicular atresia | luteal regression | bisphenol A | TOXICOLOGY | EXPRESSION | steroidogenic acute regulatory protein | ESTROUS-CYCLE | Estradiol - blood | Luteolysis - drug effects | Granulosa Cells - enzymology | Apoptosis - drug effects | Benzhydryl Compounds - toxicity | Phenols - toxicity | Down-Regulation | Rats | Luteinizing Hormone - metabolism | Rats, Sprague-Dawley | Granulosa Cells - drug effects | Aromatase - genetics | Animals | Ovary - enzymology | Female | Ovary - drug effects | Cell Proliferation - drug effects | Estradiol - biosynthesis | Follicular Atresia - drug effects | Proteins | Bisphenol A | Fluid flow | Regression | Adults | Ovaries | Hormones | Serums | Research
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7. Full Text Identification of miRNAs associated with the follicular-luteal transition in the ruminant ovary
by McBride, D and Carré, W and Sontakke, S.D and Hogg, C.O and Law, A and Donadeu, F.X and Clinton, M
Reproduction, ISSN 1470-1626, 08/2012, Volume 144, Issue 2, pp. 221 - 233
Little is known about the involvement of microRNAs (miRNAs) in the follicular-luteal transition. The aim of this study was to identify genome-wide changes in... 
LINEAGE DIFFERENTIATION | STIMULATING-HORMONE | STEM-CELLS | IN-VITRO | REPRODUCTIVE BIOLOGY | CAENORHABDITIS-ELEGANS | SMALL RNAS | GENE | DOWN-REGULATION | DEVELOPMENTAL BIOLOGY | RAT GRANULOSA-CELLS | MICRORNA EXPRESSION | Ovary - chemistry | MicroRNAs - metabolism | Gene Expression Profiling | Granulosa Cells - metabolism | Cell Differentiation - genetics | Ovarian Follicle - chemistry | MicroRNAs - isolation & purification | Cattle | Ruminants - metabolism | Corpus Luteum - chemistry | Ovarian Follicle - physiology | Luteal Phase - metabolism | Female | Ovarian Follicle - metabolism | Ovary - metabolism | Granulosa Cells - physiology | Cells, Cultured | Luteal Phase - genetics | Ruminants - genetics | Follicular Phase - genetics | Animals | Corpus Luteum - metabolism | Follicular Phase - metabolism | Theca Cells - physiology | Progesterone - metabolism | Theca Cells - metabolism | Sheep | MicroRNAs - genetics
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8. Full Text Brown adipose tissue transplantation ameliorates polycystic ovary syndrome
by Xiaoxue Yuan and Tao Hu and Han Zhao and Yuanyuan Huang and Rongcai Ye and Jun Lin and Chuanhai Zhang and Hanlin Zhang and Gang Wei and Huiqiao Zhou and Meng Dong and Jun Zhao and Haibin Wang and Qingsong Liu and Hyuek Jong Lee and Wanzhu Jin and Zi-Jiang Chen
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2016, Volume 113, Issue 10, pp. 2708 - 2713
Polycystic ovary syndrome (PCOS), which is characterized by anovulation, hyperandrogenism, and polycystic ovaries, is a complex endocrinopathy. Because the... 
Brown adipose tissue | PCOS | Transplantation | Ameliorates | Adiponectin | adiponectin | DIAGNOSIS | ameliorates | MULTIDISCIPLINARY SCIENCES | HUMANS | PREVALENCE | FEATURES | THERMOGENESIS | WOMEN | OBESITY | brown adipose tissue | INSULIN-RESISTANCE | transplantation | MASS | MICE | Adiponectin - pharmacology | Polycystic Ovary Syndrome - metabolism | Humans | Insulin Resistance | Male | Treatment Outcome | Insulin - blood | Polycystic Ovary Syndrome - chemically induced | Rats, Sprague-Dawley | Estrous Cycle - drug effects | Adiponectin - blood | Adipose Tissue, Brown - transplantation | Dehydroepiandrosterone | Animals | Analysis of Variance | Polycystic Ovary Syndrome - surgery | Infertility, Female - surgery | Adult | Female | Blood Glucose - metabolism | Energy Metabolism - drug effects | Adipose tissues | Transplantation of organs, tissues, etc | Care and treatment | Stein-Leventhal syndrome | Health aspects | Methods | Biological Sciences
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9. Full Text Hypothalamic–pituitary, ovarian and adrenal contributions to polycystic ovary syndrome
by Baskind, N. Ellissa, MBChB, MRCOG, MD and Balen, Adam H., MB, BS, MD, DSc, FRCOG
Best Practice & Research: Clinical Obstetrics & Gynaecology, ISSN 1521-6934, 2016, Volume 37, pp. 80 - 97
Polycystic ovary syndrome (PCOS) is a prevalent heterogeneous disorder linked with disturbances of reproductive, endocrine and metabolic function. The... 
Obstetrics and Gynecology | ovary | hypothalamic–hypophyseal system | physiopathology | hyperandrogenism | polycystic ovary syndrome | MENSTRUAL-CYCLE | hypophyseal system | GONADOTROPIN-RELEASING-HORMONE | ANDROGEN PRODUCTION | ANTI-MULLERIAN HORMONE | LUTEINIZING-HORMONE | OBSTETRICS & GYNECOLOGY | hypothalamic | FOLLICLE-STIMULATING-HORMONE | HUMAN THECAL CELLS | RAT GRANULOSA-CELLS | SYNDROME PCOS | ENDOTHELIAL GROWTH-FACTOR | Hyperinsulinism - metabolism | Follicle Stimulating Hormone - metabolism | Oocytes - growth & development | Polycystic Ovary Syndrome - metabolism | Ovarian Follicle - growth & development | Pituitary-Adrenal System - metabolism | Humans | Luteinizing Hormone - metabolism | Hypothalamo-Hypophyseal System - metabolism | Hyperandrogenism - etiology | Polycystic Ovary Syndrome - complications | Gonadotropin-Releasing Hormone - metabolism | Female | Hyperandrogenism - metabolism | Ovary - metabolism | Neurohormones | Brain | Androgens | Pituitary hormones | Stein-Leventhal syndrome
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10. Full Text Fertility after intact ovary transplantation
by Wang, Xiang and Wang, Xiang and Chen, Huifang and Chen, Huifang and Yin, Hang and Yin, Hang and Kim, S. Samuel and Kim, S. Samuel and Tan, Seang Lin and Tan, Seang Lin and Gosden, Roger G and Gosden, Roger G
Nature, ISSN 0028-0836, 01/2002, Volume 415, Issue 6870, pp. 385 - 385
Transplantation surgery, which is limited by the supply and short-term viability of fresh donor organs, would be revolutionized if these could survive... 
KIDNEYS | MULTIDISCIPLINARY SCIENCES | Uterus - transplantation | Animals | Cryopreservation | Fertility | Rats, Inbred Lew | Rats | Female | Ovary - physiology | Ovary - transplantation | Nitrogen | Fallopian Tubes - transplantation
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11. Full Text Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy
by Patel, Seema
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 09/2018, Volume 182, pp. 27 - 36
Polycystic ovary syndrome (PCOS) is an endocrine disorder, afflicting females of reproductive age. This syndrome leads to infertility, insulin resistance,... 
Amenorrhea | Hyperandrogenism | Anovulation | Endocrine disorder | Hyperprolactinemia | Polycystic ovary syndrome (PCOS) | C-REACTIVE PROTEIN | METFORMIN | MELATONIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | RAT MODEL | WOMEN | IN-VITRO | HORMONE | CHEMERIN | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | ASSOCIATION | Inflammation - complications | Life Style | Polycystic Ovary Syndrome - etiology | Obesity - complications | Endocrine System - physiopathology | Humans | Insulin Resistance | Female | Polycystic Ovary Syndrome - pathology | Insulin resistance | Contraceptives | Stein-Leventhal syndrome | Medical informatics
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12. Full Text Association between polycystic ovary syndrome and gut microbiota
by Guo, Yanjie and Qi, Yane and Yang, Xuefei and Zhao, Lihui and Wen, Shu and Liu, Yinhui and Tang, Li
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0153196
Polycystic ovary syndrome (PCOS) is the most frequent endocrinopathy in women of reproductive age. It is difficult to treat PCOS because of its complex... 
Ovary - pathology | Estrous Cycle - physiology | Nitriles - pharmacology | Aromatase Inhibitors - pharmacology | Microbiota - drug effects | Rats | Gastrointestinal Microbiome - physiology | Rats, Sprague-Dawley | Estrous Cycle - drug effects | Triazoles - pharmacology | Animals | Gastrointestinal Microbiome - drug effects | Polycystic Ovary Syndrome - drug therapy | Female | Polycystic Ovary Syndrome - pathology | Care and treatment | Microbiota (Symbiotic organisms) | Stein-Leventhal syndrome | Analysis | Dysbacteriosis | Disease | Pathogenesis | Science | Transplantation | Biosynthesis | Microbiota | Metabolites | Etiology | Rodents | Aromatase | Animal tissues | Fibroblasts | Feces | Immune system | Pathogens | Polycystic ovary syndrome | Medical research | Obesity | Estrus | Metabolism | Studies | Testosterone | Researchers | Cysts | Womens health | Insulin resistance | Diabetes | Endocrinology
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