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Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 2011, Volume 6, Issue 6, pp. 1286 - 1291
BACKGROUND AND OBJECTIVES: Circulating autoantibodies against the M-type phospholipase A(2) receptor (anti-PLA(2)R) were recently identified in the majority of... 
UROLOGY & NEPHROLOGY | RAT-KIDNEY | EXPERIMENTAL GLOMERULONEPHRITIS
Journal Article
Nature, ISSN 0028-0836, 09/2010, Volume 467, Issue 7313, pp. 291 - 296
Mitochondrial calcium uptake has a central role in cell physiology by stimulating ATP production, shaping cytosolic calcium transients and regulating cell... 
UNIPORTER | YEAST MITOCHONDRIA | TRANSPORT | INNER MEMBRANE | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | RAT KIDNEY MITOCHONDRIA | GLYCOPROTEIN | CALCIUM-UPTAKE | OSCILLATIONS | CELL
Journal Article
AMERICAN JOURNAL OF PATHOLOGY, ISSN 0002-9440, 08/2010, Volume 177, Issue 2, pp. 632 - 643
We recently showed in a tetracycline-controlled transgenic mouse model that overexpression of transforming growth factor (TGF)-beta 1 in renal tubules induces... 
APOPTOSIS | LOCALIZATION | GROWTH-FACTOR-BETA | TGF-BETA | RAT-KIDNEY | INTERSTITIAL FIBROSIS | PATHOLOGY | EXPRESSION | TRANSGENIC MICE | TGF-BETA-1 | TRANSDIFFERENTIATION
Journal Article
DIABETES, ISSN 0012-1797, 08/2013, Volume 62, Issue 8, pp. 2935 - 2947
Podocyte apoptosis is a critical mechanism for excessive loss of urinary albumin that eventuates in kidney fibrosis. Pharmacological doses of the mammalian... 
KIDNEY-DISEASE | MEMBRANE THICKNESS | CELLS | HYPERTROPHY | ACTIVATED PROTEIN-KINASE | RAT-KIDNEY | GROWTH | ENDOCRINOLOGY & METABOLISM | NEPHROPATHY | MTOR | TRANSGENIC MICE
Journal Article
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 2018, Volume 314, Issue 5, pp. F879 - F880
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 07/2004, Volume 114, Issue 1, pp. 5 - 14
Acute renal failure (ARF), characterized by sudden loss of the ability of the kidneys to excrete wastes, concentrate urine, conserve electrolytes, and maintain... 
ISCHEMIA-REPERFUSION INJURY | MEDICINE, RESEARCH & EXPERIMENTAL | SYNTHASE KNOCKOUT MICE | ENDOTHELIAL INJURY | RAT-KIDNEY | VASCULAR-RESPONSES | STEM-CELLS CONTRIBUTE | NITRIC-OXIDE | EPITHELIAL POLARITY | ACUTE TUBULAR-NECROSIS | MILITARY CASUALTIES
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2005, Volume 115, Issue 5, pp. 1188 - 1198
Synaptopodin is the founding member of a novel class of proline-rich actin-associated proteins highly expressed in telencephalic dendrites and renal podocytes.... 
DENDRITIC SPINES | MEDICINE, RESEARCH & EXPERIMENTAL | LOCALIZATION | PROTEIN | FILAMENTS | RAT-KIDNEY | DIFFERENTIATION | CELL-LINES | PODOCYTES | EXPRESSION | GLOMERULAR EPITHELIUM
Journal Article
Nature Cell Biology, ISSN 1465-7392, 2013, Volume 15, Issue 12, pp. 1464 - 1472
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 12/2016, Volume 57, Issue 12, pp. 1920 - 1926
Metformin is the most widely prescribed oral antiglycemic drug, with few adverse effects. However, surprisingly little is known about its human biodistribution... 
biodistribution | RAT-KIDNEY | INCREASES | metformin | EXCRETION | GENETIC-VARIATION | C-11-metformin | PET/CT | MULTIDRUG | CATION TRANSPORTERS OCT1 | EXPRESSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET | METFORMIN PHARMACOKINETICS | GLUCOSE-PRODUCTION
Journal Article
Toxicological sciences : an official journal of the Society of Toxicology, ISSN 1096-6080, 12/2018, Volume 166, Issue 2, pp. 441 - 450
Identification of improved translatable biomarkers of nephrotoxicity is an unmet safety biomarker need. Fatty-acid-binding protein 4 (FABP4) was previously... 
DIKI | FABP4 | Nephrotoxicity | Safety biomarkers | URINARY CLUSTERIN | LIVER-TYPE | nephrotoxicity | RAT-KIDNEY | TOXICOLOGY | safety biomarkers | IDENTIFICATION | EXCRETION | NEXT-GENERATION | CYSTATIN C
Journal Article
MAGNETIC RESONANCE IN MEDICINE, ISSN 0740-3194, 04/2017, Volume 77, Issue 4, pp. 1650 - 1655
Purpose: In the current study, we investigated hyperpolarized urea as a possible imaging biomarker of the renal function by means of the intrarenal osmolality... 
kidney | METABOLISM | MRI | Type 1 diabetes | RAT-KIDNEY | DISEASE | renal function | hyperpolarization | MELLITUS | PROTEINS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 07/2008, Volume 118, Issue 7, pp. 2526 - 2534
Diabetes mellitus is the most common and rapidly growing cause of end-stage renal disease in developed countries. A classic hallmark of early diabetes mellitus... 
OXYGEN | MEDICINE, RESEARCH & EXPERIMENTAL | IN-VITRO | ANGIOTENSIN SYSTEM | ACID | METABOLISM | MACULA DENSA CELLS | RAT-KIDNEY | NITRIC-OXIDE SYNTHASE | PROTEIN-COUPLED RECEPTORS | DIABETIC-NEPHROPATHY
Journal Article
Journal of magnetic resonance imaging : JMRI, ISSN 1053-1807, 4/2015, Volume 41, Issue 4, pp. 1124 - 1128
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, ISSN 1931-857X, 11/2014, Volume 307, Issue 10, pp. F1134 - F1135
Journal Article
Kidney International, ISSN 0085-2538, 03/2014, Volume 85, Issue 3, pp. 611 - 623
AMP-activated protein kinase (AMPK) is an important energy sensor that may be critical in regulating renal lipid accumulation. To evaluate the role of AMPK in... 
lysosomal dysfunction | AMPK | chronic kidney disease | lipid accumulation | obesity | SYSTEM | RAT-KIDNEY | PROTEIN-KINASE | AUTOPHAGY | GENTAMICIN | INDUCED LYSOSOMAL PHOSPHOLIPIDOSIS | PROXIMAL TUBULE CELLS | METABOLISM | DISEASE | UROLOGY & NEPHROLOGY | DIFFERENT FIXATIVES
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 01/2011, Volume 22, Issue 1, pp. 104 - 112
Journal Article
BLOOD, ISSN 0006-4971, 07/2009, Volume 114, Issue 1, pp. 49 - 59
Osteopontin (OPN), a multifunctional acidic glycoprotein, expressed by osteoblasts within the endosteal region of the bone marrow (BM) suppresses the... 
ADHESIVE PROPERTIES | IN-VITRO | COLONY-STIMULATING FACTOR | NONPHOSPHORYLATED FORMS | STRUCTURAL REQUIREMENTS | NEUTROPHIL MIGRATION | RAT-KIDNEY CELLS | BONE-MARROW | PHYSIOLOGICAL-PROPERTIES | ALPHA-4 INTEGRINS | HEMATOLOGY
Journal Article