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Journal Article
Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7656, pp. 118 - 123
Journal Article
Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7657, pp. 259 - 264
The human glucagon receptor, GCGR, belongs to the class B G-protein-coupled receptor family and plays a key role in glucose homeostasis and the pathophysiology... 
Medicine(all) | General | REFINEMENT | EXTRACELLULAR DOMAINS | LIPIDIC CUBIC PHASE | CORTICOTROPIN-RELEASING-FACTOR | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | VALIDATION | BINDING-SITE | SERIAL FEMTOSECOND CRYSTALLOGRAPHY | LIGAND | SOFTWARE | Receptors, Glucagon - agonists | Cross-Linking Reagents - chemistry | Allosteric Site - drug effects | Humans | Benzamides - metabolism | Models, Molecular | Receptors, Glucagon - metabolism | Crystallography, X-Ray | Receptors, Glucagon - classification | Molecular Dynamics Simulation | Deuterium Exchange Measurement | Disulfides - chemistry | Phenylurea Compounds - chemistry | Receptors, Glucagon - chemistry | Protein Domains | Ligands | Benzamides - pharmacology | Cell Membrane - metabolism | Phenylurea Compounds - metabolism | Phenylurea Compounds - pharmacology | Protein Stability | Benzamides - chemistry | Protein structure prediction | G proteins | Glucagon | Structure | Health aspects | Methods | Deuterium | Dynamic structural analysis | Exchanging | G protein-coupled receptors | Molecular structure | Hydrogen | Hydrogen-deuterium exchange | Diabetes mellitus | Homeostasis | Molecular dynamics | Crosslinking | Forming | Activation | Glucose | Guanine nucleotide-binding protein | Coupling (molecular) | Proteins | Signaling | Receptors | Receptor mechanisms | Diabetes | Protein structure | Crystal structure
Journal Article