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PLOS ONE, ISSN 1932-6203, 08/2019, Volume 14, Issue 8
The insulin-like growth factor-1 (IGF-1) signaling pathway has been implicated in non-small cell lung cancer (NSCLC) outcomes and resistance to targeted... 
MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | INSULIN-RECEPTOR-SUBSTRATE-1 | RESISTANCE | MUTATIONS | IGF-1R | EGFR | IGF1R
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2012, Volume 32, Issue 2, pp. 247 - 256
Journal Article
Journal Article
Kidney International, ISSN 0085-2538, 04/2011, Volume 79, Issue 8, pp. 883 - 896
Insulin resistance has been associated with the progression of chronic kidney disease in both diabetes and obesity. In order to determine the cellular... 
insulin receptor substrate-1 | protein kinase C-β | insulin resistance | diabetic nephropathy | obesity | ACTIVATION | DOWN-REGULATION | MECHANISMS | MELLITUS | NEPHROPATHY | NITRIC-OXIDE PRODUCTION | ENDOTHELIAL-CELLS | CHRONIC RENAL-DISEASE | UROLOGY & NEPHROLOGY | protein kinase C-beta | KIDNEY | PROGRESSION | Protein Kinase C beta | Phosphorylation | Diabetes Mellitus, Experimental - genetics | Maleimides - pharmacology | Kidney Glomerulus - physiopathology | Male | NF-kappa B - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Obesity - genetics | Ubiquitination | Insulin Resistance - physiology | Indoles - pharmacology | Nitric Oxide Synthase Type III - metabolism | Insulin Receptor Substrate Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Diabetes Mellitus, Experimental - physiopathology | Nitric Oxide - biosynthesis | Protein Kinase C - physiology | Signal Transduction | Insulin Receptor Substrate Proteins - physiology | RNA, Messenger - genetics | Rats | Obesity - physiopathology | Protein Kinase C - antagonists & inhibitors | Antioxidants - pharmacology | Kidney Glomerulus - pathology | Glycogen Synthase Kinase 3 - metabolism | Rats, Sprague-Dawley | Obesity - pathology | Rats, Zucker | Animals | Insulin Resistance - genetics | Diabetes Mellitus, Experimental - pathology | Receptor, Insulin - metabolism | Protein Kinase Inhibitors - pharmacology | Blood Glucose - metabolism | Proteasome Inhibitors
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 12/2017, Volume 313, Issue 6, pp. L1174 - L1187
Platelet-derived growth factor (PDGF)-A, which only signals through PDGF-receptor-alpha (PDGFR-alpha), is required for secondary alveolar septal formation.... 
Pulmonary alveoli | Lung development | Mechanotransduction | Emphysema | Cell migration | ACTIVATION | PHYSIOLOGY | FACTOR-A | COLLAGEN | ALVEOLAR SEPTATION | pulmonary alveoli | mechanotransduction | emphysema | EMERGING ROLE | RESPIRATORY SYSTEM | CELL-MIGRATION | PDGFR-ALPHA | MOUSE MODEL | cell migration | GENE-EXPRESSION | lung development | PULMONARY-FIBROSIS | rac GTP-Binding Proteins - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Pulmonary Emphysema - metabolism | Pulmonary Fibrosis - genetics | Platelet-Derived Growth Factor - genetics | rac GTP-Binding Proteins - genetics | Pulmonary Alveoli - metabolism | Pulmonary Emphysema - genetics | src-Family Kinases - metabolism | Pulmonary Fibrosis - metabolism | Neuropeptides - genetics | Rho Guanine Nucleotide Exchange Factors - metabolism | Fibroblasts - metabolism | Pulmonary Alveoli - pathology | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Pulmonary Emphysema - pathology | Neuropeptides - metabolism | Pulmonary Fibrosis - pathology | Rho Guanine Nucleotide Exchange Factors - genetics | Fibroblasts - pathology | Mice, Knockout | Phosphatidylinositol 3-Kinases - genetics | Mechanotransduction, Cellular | Platelet-Derived Growth Factor - metabolism | Animals | Receptor, Platelet-Derived Growth Factor alpha - genetics | Mice | src-Family Kinases - genetics | rac1 GTP-Binding Protein - metabolism | Cell Movement | rac1 GTP-Binding Protein - genetics
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 2009, Volume 329, Issue 2, pp. 496 - 504
Journal Article