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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ISSN 0146-0404, 05/2019, Volume 60, Issue 6, pp. 1928 - 1936
PURPOSE. Diabetes leads to the downregulation of the retinal Kir4.1 channels and Muller cell dysfunction. The insulin receptor substrate-1 (IRS-1) is a... 
CONDUCTANCE | MEMBRANE | INCREASES | Muller cell | Kir4.1 channels | diabetic retinopathy | GLIAL-CELLS | insulin receptor substrate 1 | circadian rhythm | RESISTANCE | OPHTHALMOLOGY | RETINOPATHY | MICE | RECTIFYING POTASSIUM CHANNEL | EXPRESSION | RETINAL MULLER CELLS
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 08/2013, Volume 587, Issue 15, pp. 2319 - 2324
Journal Article
International Journal of Clinical and Experimental Medicine, ISSN 1940-5901, 10/2015, Volume 8, Issue 10, pp. 17451 - 17460
The correlation between insulin receptor substrate-1 (IRS-1) rs1801278G>A polymorphism and polycystic ovary syndrome (PCOS) has been widely studied. However,... 
Insulin receptor substrate-1 | Polycystic ovary syndrome | Meta-analysis | Polymorphism | MEDICINE, RESEARCH & EXPERIMENTAL | meta-analysis | RISK | polymorphism | GENES POLYMORPHISMS | PREVALENCE | polycystic ovary syndrome | METABOLIC FEATURES | WOMEN | GLY972ARG VARIANT | PROGRESS | RESISTANCE | GLUCOSE-TOLERANCE | GLY1057ASP
Journal Article
Frontiers in Endocrinology, ISSN 1664-2392, 2014, Volume 5, p. 24
Insulin receptor substrates (IRSs) are well known to play crucial roles in mediating intracellular signals of insulin-like growth factors (IGFs)/insulin.... 
RACK1 | U96A | Insulin-like growth factor | SnoRNA | Insulin receptor substrate | BOX-C/D | PRECURSOR | IRS-1 | INTRON | BINDING-PROTEIN | INSULIN-RECEPTOR-SUBSTRATE-1 | snoRNA | NUCLEAR TRANSLOCATION | YEAST | ENDOCRINOLOGY & METABOLISM | insulin-like growth factor | insulin receptor substrate | SNORNAS | GROWTH-FACTOR-I | insulin receptor substrate (IRS)
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2012, Volume 122, Issue 4, pp. 1316 - 1338
While a potential causal factor in Alzheimer's disease (AD), brain insulin resistance has not been demonstrated directly in that disorder. We provide such a... 
DIABETES-MELLITUS | MEDICINE, RESEARCH & EXPERIMENTAL | SKELETAL-MUSCLE | RECEPTOR SUBSTRATE-1 IRS-1 | TYROSINE PHOSPHORYLATION | GLUCOSE-TRANSPORTER | CENTRAL-NERVOUS-SYSTEM | CEREBRAL-CORTEX | GROWTH-FACTOR-I | AMYLOID-BETA OLIGOMERS | TRANSGENIC MICE | Insulin-Like Growth Factor I - pharmacology | Phosphorylation | Apolipoprotein E4 - genetics | Cerebellar Cortex - metabolism | Humans | Middle Aged | Cognition Disorders - metabolism | Male | Alzheimer Disease - pathology | Brain - metabolism | Cognition Disorders - etiology | Aged, 80 and over | Female | Insulin Receptor Substrate Proteins - genetics | Insulin Receptor Substrate Proteins - chemistry | Alzheimer Disease - psychology | Drug Resistance | Insulin - pharmacology | Signal Transduction | Insulin Receptor Substrate Proteins - physiology | Insulin Resistance | Hippocampus - pathology | Recombinant Proteins - pharmacology | Phosphoserine - metabolism | Diabetes Complications - complications | Brain - drug effects | Hippocampus - metabolism | Insulin - metabolism | Insulin-Like Growth Factor I - physiology | Cerebellar Cortex - pathology | Alzheimer Disease - metabolism | Brain - pathology | Glucose - metabolism | Aged | Protein Processing, Post-Translational | Care and treatment | Insulin resistance | Insulin-like growth factors | Cellular signal transduction | Diagnosis | Research | Properties | Alzheimer's disease
Journal Article