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Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 2046 - 2058
T cell Ig and ITIM domain (TIGIT) is an inhibitory receptor expressed by activated T cells, Tregs, and NI( cells. Here, we determined that TIGIT is upregulated... 
MEDICINE, RESEARCH & EXPERIMENTAL | ADHESION MOLECULE | LIGANDS | DNAM-1 | INHIBITORY RECEPTORS | CHRONIC VIRAL-INFECTION | NECTIN-2 CD112 | UP-REGULATION | PVR CD155 | EXPRESSION | POLIOVIRUS RECEPTOR CD155 | Up-Regulation | Receptors, Immunologic - physiology | Receptors, Virus - biosynthesis | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Neoplasm Proteins - antagonists & inhibitors | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Programmed Cell Death 1 Receptor - physiology | Receptors, Virus - genetics | Receptors, Immunologic - antagonists & inhibitors | Receptors, Immunologic - biosynthesis | Programmed Cell Death 1 Receptor - biosynthesis | CD8-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Interleukin-2 Receptor beta Subunit - genetics | Neoplasm Proteins - genetics | Antibodies, Monoclonal - immunology | Antigen-Presenting Cells - metabolism | Antigens, Neoplasm - immunology | Lymphocyte Activation | Neoplasm Proteins - biosynthesis | Antibodies, Monoclonal - pharmacology | Immunophenotyping | Interleukin-2 Receptor beta Subunit - biosynthesis | Melanoma - pathology | Antigen-Presenting Cells - immunology | Melanoma - immunology | Antigens, Differentiation, T-Lymphocyte - genetics | Cell Line, Tumor | T-Cell Antigen Receptor Specificity | Immunologic Memory | Antigens, Differentiation, T-Lymphocyte - biosynthesis | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - genetics | Programmed Cell Death 1 Receptor - genetics | Cytokines - biosynthesis | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus | Abridged Index Medicus | Oncology | Immunology | Dermatology | Therapeutics
Journal Article
1996, Current topics in microbiology and immunology, ISBN 3540593446, Volume 205., x, 182
Book
Journal of Psychopharmacology, ISSN 0269-8811, 01/2009, Volume 23, Issue 1, pp. 65 - 73
Asenapine is a novel psychopharmacologic agent under development for the treatment of schizophrenia and bipolar disorder. We determined and compared the human... 
Schizophrenia | Affinity | Bipolar disorder | Asenapine | Human receptor | NEGATIVE SYMPTOMS | PSYCHIATRY | FOCUS | SEROTONIN RECEPTORS | DISORDERS | RISPERIDONE | schizophrenia | COGNITION | NEUROSCIENCES | CLINICAL NEUROLOGY | bipolar disorder | DOPAMINE D-3 RECEPTOR | PSYCHOSIS | ATYPICAL ANTIPSYCHOTIC-DRUG | PHARMACOLOGY & PHARMACY | asenapine | human receptor | affinity | Humans | Receptors, Serotonin - drug effects | Substrate Specificity | Receptors, Serotonin - genetics | Heterocyclic Compounds, 4 or More Rings - pharmacology | Psychotropic Drugs - therapeutic use | Receptors, Dopamine - drug effects | Clozapine - pharmacology | Histamine Release - genetics | Receptors, Muscarinic - drug effects | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Receptors, Adrenergic - drug effects | Psychotropic Drugs - pharmacology | Cloning, Molecular | Receptors, Adrenergic - genetics | Receptors, Dopamine D2 - drug effects | Inhibitory Concentration 50 | Molecular Structure | Radioligand Assay | Histamine Release - drug effects | Receptors, Muscarinic - genetics | Benzodiazepines - pharmacology | Heterocyclic Compounds, 4 or More Rings - chemistry | Clinical Trials as Topic | Psychotropic Drugs - chemistry | Bipolar Disorder - drug therapy | Receptors, Dopamine D2 - physiology | Schizophrenia - drug therapy | Receptors, Dopamine - genetics | Histamine receptors | Drugs | Neuroleptics | Olanzapine | Acetylcholine receptors (muscarinic) | Mental disorders | Dopamine D4 receptors | Serotonin S1 receptors | Serotonin S7 receptors | Psychotropic drugs | Receptors | Histamine H2 receptors | Risperidone | Dopamine D2 receptors | Dopamine receptors | Binding | Dopamine | Serotonin | Dopamine D3 receptors | Serotonin S6 receptors | Serotonin S2 receptors | Histamine | Dopamine D1 receptors | Serotonin receptors | Receptors (physiology) | Antagonist drugs | Psychopharmacology | Index Medicus
Journal Article
Purinergic Signalling, ISSN 1573-9538, 9/2015, Volume 11, Issue 3, pp. 389 - 407
Adenosine receptors (ARs) have emerged as new drug targets. The majority of data on affinity/potency and selectivity of AR ligands described in the literature... 
Neurosciences | Agonist | Biomedicine | Human Physiology | Cancer Research | Selectivity | Potency | Antagonist | Pharmacology/Toxicology | Species differences | Biomedicine general | XANTHINE DERIVATIVES | NEUROSCIENCES | STRIATAL MEMBRANES | PROTEIN-COUPLED ADENOSINE | P2Y RECEPTORS | A(2B) RECEPTORS | INTERNATIONAL UNION | LIGANDS | A(2A) RECEPTOR | HIGHLY POTENT | PARKINSONS-DISEASE | Cricetulus | Species Specificity | Humans | DNA, Complementary - genetics | Adenosine A1 Receptor Antagonists - pharmacology | Adenosine A2 Receptor Agonists - metabolism | Receptor, Adenosine A2B - genetics | Structure-Activity Relationship | Adenosine A1 Receptor Antagonists - metabolism | Adenosine A2 Receptor Antagonists - metabolism | Adenosine A2 Receptor Agonists - pharmacology | Adenosine A3 Receptor Agonists - pharmacology | Adenosine A1 Receptor Agonists - pharmacology | Receptor, Adenosine A2B - drug effects | Receptor, Adenosine A2A - genetics | Adenosine A3 Receptor Antagonists - pharmacology | Cell Membrane - metabolism | Adenosine A3 Receptor Agonists - metabolism | Cyclic AMP - metabolism | Arrestin - metabolism | Cell Membrane - drug effects | DNA, Complementary - drug effects | CHO Cells | Cricetinae | Receptors, Purinergic P1 - genetics | Rats | Receptor, Adenosine A2A - metabolism | Receptor, Adenosine A2B - metabolism | Receptor, Adenosine A2A - drug effects | Binding, Competitive - drug effects | Adenosine A2 Receptor Antagonists - pharmacology | Animals | Adenosine A1 Receptor Agonists - metabolism | Adenosine A3 Receptor Antagonists - metabolism | Mice | Receptors, Purinergic P1 - metabolism | Receptors, Purinergic P1 - drug effects | Adenosine | Index Medicus | Original
Journal Article
1994, ISBN 9780867208627, xii, 228
Book
Book
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0167240 - e0167240
Tamoxifen (Tam) is a selective estrogen receptor (ER) modulator (SERM) that is an essential drug to treat ER-positive breast cancer. Aside from known actions... 
SIGNAL-TRANSDUCTION | IN-VITRO | ALLOSTERIC MODULATORS | HUMAN-BREAST-CANCER | MULTIDISCIPLINARY SCIENCES | INVERSE AGONIST | CELL-GROWTH | RAT-BRAIN | ADENYLATE-CYCLASE | ESTROGEN-RECEPTOR | CB1 RECEPTOR | Cannabinoid Receptor Agonists - metabolism | Cricetulus | Receptor, Cannabinoid, CB2 - agonists | Humans | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Cannabinoid Receptor Agonists - pharmacology | Isomerism | Breast Neoplasms - metabolism | Indoles - metabolism | Cyclohexanols - metabolism | Receptor, Cannabinoid, CB1 - agonists | Colforsin - metabolism | Tamoxifen - chemistry | Cannabinoid Receptor Antagonists - pharmacology | Female | Indoles - pharmacology | Cyclohexanols - pharmacology | Cyclic AMP - metabolism | CHO Cells | Binding, Competitive | Tamoxifen - metabolism | Cricetinae | Colforsin - pharmacology | Selective Estrogen Receptor Modulators - chemistry | Adenylyl Cyclases - metabolism | Breast Neoplasms - drug therapy | Selective Estrogen Receptor Modulators - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Guanosine 5'-O-(3-Thiotriphosphate) - metabolism | Animals | Cannabinoid Receptor Antagonists - metabolism | Tamoxifen - pharmacology | Tamoxifen - analogs & derivatives | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Selective Estrogen Receptor Modulators - pharmacology | GTP-Binding Proteins - metabolism | Cell receptors | Patient outcomes | Drug metabolism | Development and progression | Genetic aspects | Breast cancer | Tamoxifen | Drug therapy | Health aspects | Cytochrome | Drugs | Estrogens | Estrogen receptors | Drug development | Isomers | Proteins | Adenylate cyclase | Osteoporosis | Receptors | Toxicology | Cell growth | Metabolites | Cannabinoid CB2 receptors | Cannabinoid receptors | Medical treatment | Cytochrome P450 | Pharmacology | Cannabinoid CB1 receptors | FDA approval | Medicine | Studies | Inverse agonists | Affinity | Selective estrogen receptor modulators | Cancer | Index Medicus
Journal Article
1988, Neurology and neurobiology, ISBN 9780845127377, Volume 35, xi, 548
Book
1981, ISBN 041215840X, Volume 12., ix, 365
Book
2003, Methods in enzymology, ISBN 9780121822675, Volume 364., xliv, 536 p., [20] p. of plates
Nuclear Receptors are inducible transcription factors that mediate complex effects on development, differentiation and homeostasis. They regulate the... 
Complexes récepteur-ligand | Receptor-ligand complexes | Nuclear receptors (Biochemistry) | Récepteurs nucléaires (Biochimie) | Hormone receptors | Handbooks, manuals, etc
Book
1988, ISBN 0306427087, xv, 235
Book
2007, Advances in experimental medicine and biology, ISBN 9780387706290, Volume 597., xix, 206
It has been established that TNF receptor associated factors (TRAFs) are critical signaling mediators for not only the TNF receptor superfamily, but also the... 
Tumor necrosis factor | Receptors | Cellular signal transduction | Life Sciences | Developmental Biology | Cell Biology
Book
The International journal of biological markers, ISSN 0393-6155, 1986
Journal
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