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Nature genetics, ISSN 1546-1718, 2013, Volume 45, Issue 12, pp. 1439 - 1445
Journal Article
Toxicology and applied pharmacology, ISSN 0041-008X, 2008, Volume 232, Issue 3, pp. 384 - 395
Benzophenone (BP) derivatives, BP1 (2,4-dihydroxybenzophenone), BP2 (2,2′,4,4′-tetrahydroxybenzophenone), BP3 (2-hydroxy-4-methoxybenzophenone), and THB... 
Benzophenones (BPs) | Human estrogen receptor alpha and beta (hERα and hERβ) | Receptor binding assay | Human androgen receptor (hAR) | Reporter gene assay | Rainbow trout estrogen receptor alpha (rtERα) | Vitellogenin (Vtg) | Cell proliferation assay | Estrogenic activity | REPORTER CELL-LINES | RAINBOW-TROUT | Human estrogen receptor alpha and beta (hER alpha and hER beta) | ER-BETA | Rainbow trout estrogen receptor alpha (rtER alpha) | 4-METHYLBENZYLIDENE CAMPHOR | BREAST-CANCER CELLS | SYNTHETIC CHEMICALS | RAT UTEROTROPHIC ASSAY | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | TROUT ONCORHYNCHUS-MYKISS | UV FILTERS | Estradiol - metabolism | Humans | Androgen Antagonists - pharmacology | Benzophenones - pharmacology | Oncorhynchus mykiss | Estrogen Receptor beta - drug effects | Dose-Response Relationship, Drug | Estrogen Receptor alpha - drug effects | Animals | Endocrine Disruptors - pharmacology | Biological Assay | Cell Proliferation - drug effects | Vitellogenins - biosynthesis | Phenols | Gene expression | Trout | Estradiol | Fishes | Analysis | Index Medicus | Cell Proliferation | Androgen Antagonists | Endocrine Disruptors | Life Sciences | Toxicology | Estrogen Receptor alpha | Benzophenones | Vitellogenins | Estrogen Receptor beta | HAIR | CELL PROLIFERATION | INDUCTION | 60 APPLIED LIFE SCIENCES | BIOASSAY | IN VITRO | TROUT | DRUGS | ESTRADIOL | GENES | BENZOPHENONE | LIVER CELLS | CONSUMER PRODUCTS | ANDROGENS | RECEPTORS
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2007, Volume 130, Issue 5, pp. 811 - 823
Estrogen prevents osteoporotic bone loss by attenuating bone resorption; however, the molecular basis for this is unknown. Here, we report a critical role for... 
HUMDISEASE | DEVBIO | SIGNALING | ANDROGEN RECEPTOR | APOPTOSIS | RESORPTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | OSTEOPETROSIS | MICE LACKING | CELL BIOLOGY | Fas Ligand Protein - metabolism | Male | fas Receptor - metabolism | Bone Remodeling - drug effects | Selective Estrogen Receptor Modulators - therapeutic use | Estrogen Receptor alpha - metabolism | Female | Integrases - metabolism | Mice, Inbred DBA | Cell Differentiation | Estradiol - metabolism | Osteoclasts - pathology | Bone Density | Cathepsin K | Ovariectomy | Signal Transduction | Bone Diseases, Metabolic - prevention & control | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Osteoclasts - metabolism | Estrogen Receptor alpha - deficiency | Mice, Knockout | Bone Diseases, Metabolic - metabolism | Estrogen Receptor alpha - drug effects | Phenotype | Animals | Estrogen Receptor alpha - genetics | Cathepsins - genetics | Cathepsins - metabolism | Tamoxifen - therapeutic use | Tamoxifen - pharmacology | Mice | Bone Diseases, Metabolic - physiopathology | Fas Ligand Protein - genetics | Integrases - genetics | Selective Estrogen Receptor Modulators - pharmacology | Osteoclasts - drug effects | Apoptosis | Cathepsins | Antigens, CD95 | Estradiol | Life Sciences | Estrogen Receptor alpha | Biochemistry, Molecular Biology | Tamoxifen | Bone Diseases, Metabolic | Integrases | Fas Ligand Protein | Selective Estrogen Receptor Modulators | Osteoclasts | Molecular biology | Bone Remodeling
Journal Article
Molecular cell, ISSN 1097-2765, 2017, Volume 65, Issue 6, pp. 1122 - 1135.e5
Human breast cancers that exhibit high proportions of immune cells and elevated levels of pro-inflammatory cytokines predict poor prognosis. Here, we... 
crystallography | estrogen receptor | inflammation | breast cancer | cytokines | drug resistance | tamoxifen | ACTIVATION | PROTEIN | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESTROGEN-RECEPTOR-ALPHA | TAMOXIFEN RESISTANCE | LIGAND | NF-KAPPA-B | BINDING | ER-ALPHA | CELLULAR-RESPONSE | CELL BIOLOGY | Neoplasms, Hormone-Dependent - metabolism | Tumor Necrosis Factor-alpha - metabolism | Phosphorylation | Humans | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Structure-Activity Relationship | Breast Neoplasms - metabolism | Neoplasms, Hormone-Dependent - genetics | Dose-Response Relationship, Drug | Transfection | I-kappa B Kinase - metabolism | MCF-7 Cells | RNA Interference | Interleukin-1beta - metabolism | Inflammation Mediators - metabolism | Estrogen Receptor alpha - metabolism | Female | Transcription, Genetic | Estrogen Receptor alpha - chemistry | Antineoplastic Agents, Hormonal - pharmacology | Cytokines - metabolism | I-kappa B Kinase - genetics | Breast Neoplasms - drug therapy | Molecular Dynamics Simulation | Hep G2 Cells | Estrogen Receptor alpha - drug effects | Drug Resistance, Neoplasm - genetics | Breast Neoplasms - genetics | Estrogen Receptor alpha - genetics | Signal Transduction - drug effects | Breast Neoplasms - pathology | Neoplasms, Hormone-Dependent - pathology | Tamoxifen - pharmacology | Tamoxifen - analogs & derivatives | Protein Conformation | HeLa Cells | Neoplasms, Hormone-Dependent - drug therapy | Selective Estrogen Receptor Modulators - pharmacology | Medical colleges | Cytokines | Analysis | Cancer cells | Estrogen | Physiological aspects | Development and progression | Breast cancer | Gene expression | Drug resistance
Journal Article
Toxicological sciences, ISSN 1096-0929, 2015, Volume 148, Issue 1, pp. 137 - 154
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 04/2016, Volume 126, Issue 4, pp. 1525 - 1537
Journal Article
Endocrinology (Philadelphia), ISSN 1945-7170, 2009, Volume 150, Issue 5, pp. 2109 - 2117
Journal Article
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2009, Volume 119, Issue 10, pp. 3011 - 3023
Cytokines orchestrate the tumor-promoting interplay between malignant cells and the immune system. In many experimental and human cancers, the cytokine... 
RHEUMATOID-ARTHRITIS | MEDICINE, RESEARCH & EXPERIMENTAL | TGF-BETA | INTERLEUKIN-17 FAMILY | IN-VIVO | GROWTH | IL-17-PRODUCING T-CELLS | FACTOR RECEPTOR P55 | PHASE-II | NECROSIS-FACTOR-ALPHA | NF-KAPPA-B | Humans | Tumor Necrosis Factor-alpha - genetics | Interleukin-17 - immunology | Antibodies, Monoclonal - therapeutic use | Gene Expression Profiling | Chimera - genetics | CD4-Positive T-Lymphocytes - immunology | Interleukin-23 - genetics | Ovarian Neoplasms - genetics | Chimera - immunology | Interleukin-2 Receptor alpha Subunit - genetics | Infliximab | Microarray Analysis | Tumor Necrosis Factor-alpha - immunology | Anti-Inflammatory Agents - therapeutic use | Female | Ovarian Neoplasms - drug therapy | Disease Models, Animal | Interleukin-2 Receptor alpha Subunit - immunology | Receptors, Interleukin - immunology | Mice, Inbred C57BL | Receptors, Tumor Necrosis Factor, Type I | Interleukin-17 - genetics | Clinical Trials as Topic | Receptors, Interleukin - genetics | Interleukin-23 - immunology | Mice, Knockout | Animals | Signal Transduction - physiology | Mice | Ovarian Neoplasms - immunology | Interleukin-2 Receptor alpha Subunit | Signal Transduction | Anti-Inflammatory Agents | Interleukin-23 | Receptors, Interleukin | Antibodies, Monoclonal | Tumor Necrosis Factor-alpha | Life Sciences | Immunology | CD4-Positive T-Lymphocytes | Interleukin-17 | Ovarian Neoplasms | Chimera
Journal Article