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PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e30434
HemaMax, a recombinant human interleukin-12 (IL-12), is under development to address an unmet medical need for effective treatments against acute radiation... 
PROGENITOR CELLS | NERVOUS-SYSTEM | NATURAL-KILLER-CELLS | IN-VITRO | INTERFERON-GAMMA | DENDRITIC CELLS | HEMATOPOIETIC STEM-CELLS | BIOLOGY | IONIZING-RADIATION | STROMAL CELLS | DOSE INTERLEUKIN-12 | Recombinant Proteins - therapeutic use | Humans | Male | Macaca mulatta | Interferon-gamma - metabolism | Hematopoiesis - drug effects | Dose-Response Relationship, Drug | Radiation Injuries, Experimental - drug therapy | Female | Interleukin-12 - therapeutic use | Osteoblasts - cytology | Megakaryocytes - cytology | Lipopolysaccharide Receptors - biosynthesis | Biomarkers - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Recombinant Proteins - chemistry | Treatment Outcome | Animals | Receptors, Interleukin-12 - metabolism | Hematopoietic Stem Cells - cytology | Interleukin-12 - chemistry | Leukocytes, Mononuclear - cytology | Mice | Intestine, Small - metabolism | Ionizing radiation | Erythropoietin | Dendritic cells | Interleukins | Primates | Interferon | Biological response modifiers | Femur | Radiation | Mesothelioma | Monkeys | Body weight loss | Osteoblasts | Recovery | Blood | Hematopoiesis | Bone marrow | Biocompatibility | Megakaryocytes | Nuclear power plants | Growth factors | Drug dosages | Radiation effects | Pharmacodynamics | Cytokines | Interleukin 12 | Leukocytes (neutrophilic) | Statistical tests | Interleukin 15 | Survival | Interleukin 18 | Mitigation | γ-Interferon | Stem cells | Irradiation | Neopterin | Radiation damage | Osteoprogenitor cells | Neurosciences | Interleukin | Medical services | Multiple myeloma | Fuel consumption | Biomedical materials | Blood platelets | Lymphocytes | Rodents | Radiation injuries | Recombinant | Cell survival | Terrorism | Pharmacology | Hemopoiesis | White blood cells | Equivalence | Pharmacokinetics | Chemokines | Apoptosis
Journal Article
Cytokine and Growth Factor Reviews, ISSN 1359-6101, 2015, Volume 26, Issue 5, pp. 559 - 568
Journal Article
Protein Expression and Purification, ISSN 1046-5928, 10/2014, Volume 102, Issue C, pp. 76 - 84
Journal Article
World Journal of Clinical Oncology, ISSN 2218-4333, 04/2017, Volume 8, Issue 2, pp. 158 - 167
To evaluate the treatment effects of recombinant human interleukin-12 (rhIL-12) on radiotherapy complications, such as severe myelosuppression or pancytopenia,... 
Cancer prevention | Clinical research | Recombinant human interleukin-12 | Radiotherapy complications | Clinical Trials Study
Journal Article
Enzyme and Microbial Technology, ISSN 0141-0229, 2010, Volume 46, Issue 5, pp. 347 - 351
Journal Article
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2006, Volume 55, Issue 5, pp. 807 - 813
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 08/2019, Volume 25, Issue 16, pp. 4955 - 4965
Purpose: mAbs including cetuximab can induce antibody-dependent cellular cytotoxicity (ADCC) and cytokine production mediated via innate immune cells with the... 
CYTOKINE RESPONSE | GROWTH-FACTOR RECEPTOR | SINGLE-AGENT | RECOMBINANT HUMAN INTERLEUKIN-12 | NATURAL-KILLER-CELLS | EFFECTOR FUNCTIONS | ONCOLOGY | FC-GAMMA-RIIIA | I TRIAL | SUPPRESSOR-CELLS | T-CELLS
Journal Article
Blood, ISSN 0006-4971, 05/2012, Volume 119, Issue 18, pp. 4133 - 4141
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 10/2017, Volume 61, pp. 114 - 123
Journal Article