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Cell Reports, ISSN 2211-1247, 02/2016, Volume 14, Issue 7, pp. 1761 - 1773
Interleukin (IL)-11 has been shown to be a crucial factor for intestinal tumorigenesis, lung carcinomas, and asthma. IL-11 is thought to exclusively mediate... 
ADAM10 | ADAM17 | interleukin-11 | signal transduction | proteolysis | Signal transduction | Interleukin-11 | Proteolysis | MURINE INTERLEUKIN-11 | INFLAMMATION | GLYCOPROTEIN 130 | FAMILY CYTOKINE | SOLUBLE IL-6 | RECEPTOR ALPHA-CHAIN | EXPRESSION | TUMORIGENESIS | IL-6 RECEPTOR | CELL BIOLOGY
Journal Article
Biochimie, ISSN 0300-9084, 12/2015, Volume 119, pp. 175 - 182
Interleukin (IL)-6 and IL-11 are the only canonical members of the IL-6 family of cytokines that induce signaling through a homodimer of the common β-receptor... 
Signal transduction | Proliferation | Interleukin-11 | Proteolysis | Plasticity | Interleukin-6 | ACTIVATION | HUMAN IL-6 RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | GP130 | LEUKEMIA INHIBITORY FACTOR | CYTOKINE | SIGNAL-TRANSDUCTION | ONCOSTATIN-M | GLYCOPROTEIN 130 | CILIARY NEUROTROPHIC FACTOR | BINDING | Protein Subunits | Receptors, Interleukin-6 - chemistry | Cell Proliferation | Cytokine Receptor gp130 - genetics | Humans | Interleukin-11 Receptor alpha Subunit - agonists | Cytokine Receptor gp130 - agonists | Interleukin-6 Receptor alpha Subunit - metabolism | Interleukin-6 Receptor alpha Subunit - agonists | Protein Interaction Domains and Motifs | Interleukin-11 Receptor alpha Subunit - genetics | Binding Sites | Interleukin-6 - metabolism | Peptide Fragments - genetics | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Cell Line | Peptide Fragments - metabolism | Cytokine Receptor gp130 - metabolism | Interleukin-6 - genetics | Signal Transduction | Receptors, Interleukin-6 - genetics | Cytokine Receptor gp130 - chemistry | Models, Molecular | Recombinant Proteins - chemistry | Interleukin-11 - genetics | Interleukin-11 - metabolism | Interleukin-11 Receptor alpha Subunit - metabolism | Interleukin-6 Receptor alpha Subunit - chemistry | Interleukin-6 Receptor alpha Subunit - genetics | Peptide Fragments - chemistry | Animals | Interleukin-11 Receptor alpha Subunit - chemistry | Peptide Fragments - agonists | Ligands | Mice | Receptors, Interleukin-6 - agonists | Receptors, Interleukin-6 - metabolism
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 52, pp. 15928 - 15933
Journal Article
Molecules, ISSN 1420-3049, 12/2016, Volume 21, Issue 12, pp. 1632 - 1632
Journal Article
Journal Article
Cell reports, ISSN 2211-1247, 02/2016, Volume 14, Issue 7, p. 1761
Journal Article
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 11/2018, Volume 107, Issue 11, pp. 2755 - 2763
Treating thrombocytopenia induced by chemotherapy remains an unmet-medical need. The use of recombinant human interleukin-11 (rhIL-11) requires repeated... 
plasma expansion | PEGylation | dilutional anemia | fluid retention | interleukin | IL-11 | chemotherapy-induced thrombocytopenia | CHEMISTRY, MEDICINAL | FORM | CHEMICAL-MODIFICATION | IDENTIFICATION | THROMBOPOIETIN-RECEPTOR AGONISTS | CHEMISTRY, MULTIDISCIPLINARY | RECOMBINANT HUMAN INTERLEUKIN-11 | RHIL-11 | PHARMACOLOGY & PHARMACY
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, p. e101947
Journal Article