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1. Medical Therapy for Heart Failure With Reduced Ejection Fraction: The CHAMP-HF Registry
by Greene, Stephen J and Butler, Javed and Albert, Nancy M and DeVore, Adam D and Sharma, Puza P and Duffy, Carol I and Hill, C. Larry and McCague, Kevin and Mi, Xiaojuan and Patterson, J. Herbert and Spertus, John A and Thomas, Laine and Williams, Fredonia B and Hernandez, Adrian F and Fonarow, Gregg C
Journal of the American College of Cardiology, ISSN 0735-1097, 07/2018, Volume 72, Issue 4, pp. 351 - 366
reduced ejection fraction | registry | dose | medication | Severity of Illness Index | Mineralocorticoid Receptor Antagonists - administration & dosage | United States - epidemiology | Age Factors | Humans | Middle Aged | Heart Failure - physiopathology | Male | Socioeconomic Factors | Heart Failure - drug therapy | Mineralocorticoid Receptor Antagonists - therapeutic use | Dose-Response Relationship, Drug | Stroke Volume | Quality Improvement | Registries - statistics & numerical data | Female | Aged | Angiotensin Receptor Antagonists - therapeutic use | Heart Failure - epidemiology | Adrenergic beta-Antagonists - administration & dosage | Drug Utilization - statistics & numerical data | Adrenergic beta-Antagonists - therapeutic use | Angiotensin Receptor Antagonists - administration & dosage | Practice Guidelines as Topic | Health care | Angiotensin-converting enzyme inhibitors | Drugs | Therapy | Cardiac arrhythmia | Health services | Medical records | Clinical trials | Cardiovascular disease | Secondary schools | Regulatory approval | Renal insufficiency | Enzyme inhibitors | Peptidyl-dipeptidase A | Blood pressure | Cardiology | Angiotensin II | Heart diseases | Age | Heart failure | Hypertension | Mortality | Hospitalization | Patients | Asthma | Heart rate | Ethnicity | Inhibitors | Coronary vessels | Angiotensin | Neprilysin | Diabetes | Clinical medicine | Females | Hispanics | Ejection fraction
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2. Full Text Biomarkers for characterization of heart failure – Distinction of heart failure with preserved and reduced ejection fraction
by Sinning, Christoph and Kempf, Tibor and Schwarzl, Michael and Lanfermann, Simon and Ojeda, Francisco and Schnabel, Renate B and Zengin, Elvin and Wild, Philipp S and Lackner, Karl-J and Munzel, Thomas and Blankenberg, Stefan and Wollert, Kai C and Zeller, Tanja and Westermann, Dirk
International journal of cardiology, ISSN 0167-5273, 2016, Volume 227, pp. 272 - 277
Cardiovascular | Heart failure | Heart failure with reduced and preserved ejection fraction | Soluble source of tumorigenicity 2 | C-reactive protein | Growth-differentiation factor-15 | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Predictive Value of Tests | Prognosis | Humans | Middle Aged | Male | Biomarkers - blood | Heart Failure - blood | Stroke Volume | C-Reactive Protein - metabolism | Growth Differentiation Factor 15 - blood | Peptide Fragments - blood | Interleukin-1 Receptor-Like 1 Protein - blood | Adult | Female | Aged | Heart Failure - diagnosis | Natriuretic Peptide, Brain - blood | Heart Failure - mortality | Analysis | Biological markers | Index Medicus
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3. Full Text Effect of Natriuretic Peptide–Guided Therapy on Hospitalization or Cardiovascular Mortality in High-Risk Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial
by Felker, G. Michael and Anstrom, Kevin J and Adams, Kirkwood F and Ezekowitz, Justin A and Fiuzat, Mona and Houston-Miller, Nancy and Januzzi, James L and Mark, Daniel B and Piña, Ileana L and Passmore, Gayle and Whellan, David J and Yang, Hongqiu and Cooper, Lawton S and Leifer, Eric S and Desvigne-Nickens, Patrice and O’Connor, Christopher M
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 08/2017, Volume 318, Issue 8, pp. 713 - 720
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Single-Blind Method | Humans | Middle Aged | Ventricular Dysfunction - drug therapy | Heart Failure - physiopathology | Hospitalization - statistics & numerical data | Male | Biomarkers - blood | Heart Failure - blood | Heart Failure - drug therapy | Stroke Volume | Heart Failure - therapy | Treatment Failure | Peptide Fragments - blood | Cardiovascular Diseases - mortality | Female | Aged | Natriuretic Peptide, Brain - blood | Heart failure | Heart | Brain natriuretic peptide | Therapy | Peptides | Risk groups | Mortality | Clinical trials | Patients | Risk factors | Biomarkers | Strategy | Titration | Drug therapy | Cardiovascular diseases | Heart diseases | Biochemical markers | Index Medicus | Abridged Index Medicus | heart failure with reduced ejection fraction | amino-terminal pro–B-type natriuretic peptide | patient outcomes
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4. Full Text Effect of eplerenone in patients with heart failure and reduced ejection fraction: Potential effect modification by abdominal obesity. Insight from the EMPHASIS-HF trial
by Olivier, Arnaud and Pitt, Bertram and Girerd, Nicolas and Lamiral, Zohra and Machu, Jean-Loup and McMurray, John J. V and Swedberg, Karl and van Veldhuisen, Dirk J and Collier, Timothy J and Pocock, Stuart J and Rossignol, Patrick and Zannad, Faiez and Pizard, Anne and Sahlgrenska akademin and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
European journal of heart failure, ISSN 1388-9842, 09/2017, Volume 19, Issue 9, pp. 1186 - 1197
CARDIAC-FUNCTION | CARDIOMETABOLIC RISK | Heart failure with reduced ejection fraction | MINERALOCORTICOID RECEPTOR ANTAGONISM | Abdominal obesity | PARADOX | Eplerenone | WAIST CIRCUMFERENCE | ALDOSTERONE BLOCKADE | CARDIOVASCULAR-DISEASE | BODY-MASS INDEX | ADIPOCYTE DYSFUNCTION | ADIPOSE-TISSUE | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Mineralocorticoid Receptor Antagonists - administration & dosage | Heart Failure, Systolic - drug therapy | Spironolactone - administration & dosage | Humans | Middle Aged | Obesity, Abdominal - diagnosis | Obesity, Abdominal - metabolism | Mineralocorticoid Receptor Antagonists - adverse effects | Male | Treatment Outcome | Ventricular Dysfunction, Left - diagnosis | Ventricular Dysfunction, Left - mortality | Drug Monitoring - methods | Stroke Volume | Ventricular Dysfunction, Left - metabolism | Heart Failure, Systolic - metabolism | Aldosterone - metabolism | Obesity, Abdominal - complications | Female | Heart Failure, Systolic - diagnosis | Aged | Spironolactone - analogs & derivatives | Spironolactone - adverse effects | Heart Failure, Systolic - complications | Index Medicus | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Klinisk medicin
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5. Full Text Murine Models of Heart Failure With Preserved Ejection Fraction: A “Fishing Expedition”
by Valero-Muñoz, Maria and Backman, Warren and Sam, Flora
JACC. Basic to translational science, ISSN 2452-302X, 12/2017, Volume 2, Issue 6, pp. 770 - 789
comorbidities | HFpEF | murine model
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6. Sacubitril/Valsartan in Advanced Heart Failure With Reduced Ejection Fraction Rationale and Design of the LIFE Trial
by Mann, Douglas L and Greene, Stephen J and Givertz, Michael M and Vader, Justin M and Starling, Randall C and Ambrosy, Andrew P and Shah, Palak and McNulty, Steven E and Mahr, Claudius and Gupta, Divya and Redfield, Margaret M and Lala, Anuradha and Lewis, Gregory D and Mohammed, Selma F and Gilotra, Nisha A and DeVore, Adam D and Gorodeski, Eiran Z and Desvigne-Nickens, Patrice and Hernandez, Adrian F and Braunwald, Eugene and LIFE Investigators
JACC. Heart failure, ISSN 2213-1779, 10/2020, Volume 8, Issue 10, pp. 789 - 799
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Pandemics | Humans | Natriuretic Peptide, Brain - metabolism | Heart Failure - physiopathology | Hospitalization - statistics & numerical data | Aminobutyrates - therapeutic use | COVID-19 | Cardiotonic Agents - therapeutic use | Dose-Response Relationship, Drug | Early Termination of Clinical Trials | SARS-CoV-2 | Betacoronavirus | Heart-Assist Devices | Coronavirus Infections | Peptide Fragments - metabolism | Glomerular Filtration Rate | Double-Blind Method | Heart Transplantation | Heart Failure - metabolism | Hypotension - chemically induced | Heart Failure - drug therapy | Stroke Volume | Pneumonia, Viral | Tetrazoles - therapeutic use | Angiotensin Receptor Antagonists - therapeutic use | Drug Combinations
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7. Full Text The prevalence and importance of frailty in heart failure with reduced ejection fraction – an analysis of PARADIGM‐HF and ATMOSPHERE
by Dewan, Pooja and Jackson, Alice and Jhund, Pardeep S and Shen, Li and Ferreira, João Pedro and Petrie, Mark C and Abraham, William T and Desai, Akshay S and Dickstein, Kenneth and Køber, Lars and Packer, Milton and Rouleau, Jean L and Solomon, Scott D and Swedberg, Karl and Zile, Michael R and McMurray, John J.V and Sahlgrenska akademin and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
European journal of heart failure, ISSN 1388-9842, 11/2020, Volume 22, Issue 11, pp. 2123 - 2133
Frailty | Heart failure with reduced ejection fraction | Outcomes | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Index Medicus | Kardiologi | Cardiac and Cardiovascular Systems | enalapril | index | risk | older-adults | biomarker
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8. Titration of Medical Therapy for Heart Failure With Reduced Ejection Fraction
by Greene, Stephen J and Fonarow, Gregg C and DeVore, Adam D and Sharma, Puza P and Vaduganathan, Muthiah and Albert, Nancy M and Duffy, Carol and Hill, Larry and McCague, Kevin and Patterson, J. Herbert and Spertus, John A and Thomas, Laine and Williams, Fredonia B and Hernandez, Adrian F and Butler, Javed
Journal of the American College of Cardiology, ISSN 0735-1097, 05/2019, Volume 73, Issue 19, pp. 2365 - 2383
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Prospective Studies | Humans | Middle Aged | Heart Failure - physiopathology | Male | Heart Failure - drug therapy | Dose-Response Relationship, Drug | Stroke Volume | Ventricular Dysfunction, Left - drug therapy | Quality of Life | Female | Aged | Drug Therapy, Combination | Angiotensin-converting enzyme inhibitors | Heart | Drugs | Therapy | Identification methods | Clinical trials | Cardiovascular disease | Secondary schools | Multivariate analysis | Beta blockers | Confidence intervals | Enzyme inhibitors | Peptidyl-dipeptidase A | Education | Blood pressure | Angiotensin II | Heart diseases | Heart failure | Medical research | Family income | Enrollments | Hospitalization | Patients | Quality of life | Ethnicity | Inhibitors | Quality control | Angiotensin | Titration | Neprilysin | Clinical medicine | Ejection fraction
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9. Contemporary Drug Treatment of Chronic Heart Failure With Reduced Ejection Fraction: The CHECK-HF Registry
by Brunner-La Rocca, Hans-Peter and Linssen, Gerard C and Smeele, Frank J and van Drimmelen, Annemarie A and Schaafsma, Henk-Jan and Westendorp, Paul H and Rademaker, Philip C and van de Kamp, Hendrik J and Hoes, Arno W and Brugts, Jasper J and CHECK-HF Investigators
JACC. Heart failure, ISSN 2213-1779, 01/2019, Volume 7, Issue 1, pp. 13 - 21
heart failure | reduced ejection fraction | registry | treatment | guideline adherence | HFrEF | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology
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10. Full Text Medical Therapy for Heart Failure With Reduced Ejection Fraction
by Greene, Stephen J and Butler, Javed and Albert, Nancy M and DeVore, Adam D and Sharma, Puza P and Duffy, Carol I and Hill, C. Larry and McCague, Kevin and Mi, Xiaojuan and Patterson, J. Herbert and Spertus, John A and Thomas, Laine and Williams, Fredonia B and Hernandez, Adrian F and Fonarow, Gregg C
Journal of the American College of Cardiology, ISSN 0735-1097, 07/2018, Volume 72, Issue 4, pp. 351 - 366
reduced ejection fraction | registry | dose | medication | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology
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11. Digoxin Discontinuation and Outcomes in Patients With Heart Failure With Reduced Ejection Fraction
by Malik, Awais and Masson, Ravi and Singh, Steven and Wu, Wen-Chih and Packer, Milton and Pitt, Bertram and Waagstein, Finn and Morgan, Charity J and Allman, Richard M and Fonarow, Gregg C and Ahmed, Ali
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2019, Volume 74, Issue 5, pp. 617 - 627
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | United States - epidemiology | Survival Rate - trends | Humans | Risk Factors | Heart Failure - physiopathology | Stroke Volume - physiology | Patient Readmission - trends | Male | Treatment Outcome | Withholding Treatment | Cause of Death | Heart Failure - drug therapy | Propensity Score | Cardiotonic Agents - administration & dosage | Outpatients | Digoxin - administration & dosage | Female | Registries | Aged | Retrospective Studies | Heart Failure - mortality | Heart failure | Angiotensin-converting enzyme inhibitors | Heart | Enzymes | Digoxin | Mortality | Clinical trials | Beta blockers | Patients | Discharge | Confidence intervals | Enzyme inhibitors | Peptidyl-dipeptidase A | Government programs | Angiotensin | Blood pressure | Health risk assessment | Heart diseases | Ejection fraction
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12. Full Text B-Type Natriuretic Peptide in Heart Failure With Preserved Ejection Fraction　― Relevance to Age-Related Left Ventricular Modeling in Japanese
by Harada, Eisaku and Mizuno, Yuji and Kugimiya, Fumihito and Shono, Makoto and Maeda, Hiroyuki and Yano, Naotsugu and Kuwahara, Koichiro and Yasue, Hirofumi
Circulation journal : official journal of the Japanese Circulation Society, ISSN 1346-9843, 2017, Volume 81, Issue 7, pp. 1006 - 1013
LV diastolic function | B-type natriuretic peptide | Heart failure with reduced EF | Heart failure with preserved EF | LV concentric remodeling/hypertrophy | Age Factors | Humans | Middle Aged | Heart Failure - physiopathology | Male | Heart Failure - blood | Ventricular Dysfunction, Left - physiopathology | Aging - blood | Ventricular Remodeling | Ventricular Dysfunction, Left - blood | Sex Factors | Aged, 80 and over | Female | Aged | Natriuretic Peptide, Brain - blood | Index Medicus
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13. Effect of Empagliflozin on Hemodynamics in Patients With Heart Failure and Reduced Ejection Fraction
by Omar, Massar and Jensen, Jesper and Frederiksen, Peter H and Kistorp, Caroline and Videbæk, Lars and Poulsen, Mikael Kjær and Möller, Sören and Ali, Mulham and Gustafsson, Finn and Køber, Lars and Borlaug, Barry A and Schou, Morten and Møller, Jacob Eifer
Journal of the American College of Cardiology, ISSN 0735-1097, 12/2020, Volume 76, Issue 23, pp. 2740 - 2751
exercise | heart failure reduced ejection fraction | SGLT2 inhibitor | hemodynamics
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14. Health-Related Quality of Life in Heart Failure With Preserved Ejection Fraction The PARAGON-HF Trial
by Chandra, Alvin and Vaduganathan, Muthiah and Lewis, Eldrin F and Claggett, Brian L and Rizkala, Adel R and Wang, Wenyan and Lefkowitz, Martin P and Shi, Victor C and Anand, Inder S and Ge, Junbo and Lam, Carolyn S. P and Maggioni, Aldo P and Martinez, Felipe and Packer, Milton and Pfeffer, Marc A and Pieske, Burkert and Redfield, Margaret M and Rouleau, Jean L and van Veldhuisen, Dirk J and Zannad, Faiez and Zile, Michael R and McMurray, John J. V and Solomon, Scott D and PARAGON-HF Investigators
JACC. Heart failure, ISSN 2213-1779, 10/2019, Volume 7, Issue 10, pp. 862 - 874
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology
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