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Journal Article
Nature Reviews Disease Primers, ISSN 2056-676X, 12/2016, Volume 2, Issue 1, p. 16090
Lyme borreliosis is a tick-bornedisease that predominantly occurs in temperate regions of the northern hemisphere and is primarily caused by the bacterium... 
UNITED-STATES | TICK-BORNE ENCEPHALITIS | TOLL-LIKE RECEPTOR-2 | ERYTHEMA MIGRANS | MEDICINE, GENERAL & INTERNAL | B-CELL RESPONSES | BURGDORFERI SENSU-LATO | ANTIBIOTIC-REFRACTORY ARTHRITIS | ACRODERMATITIS CHRONICA ATROPHICANS | HUMAN GRANULOCYTIC ANAPLASMOSIS | PREVENT LYME
Journal Article
Journal Article
Pathogens and Disease, ISSN 2049-632X, 2017, Volume 75, Issue 2
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 05/2017, Volume 69, Issue 5, pp. 964 - 975
Objective Prevotella copri, an intestinal microbe, may overexpand in stool samples from patients with new‐onset rheumatoid arthritis (RA), but it is not yet... 
TARGET | B-CELL RESPONSES | COMMENSAL | PEPTIDES | PERIODONTITIS | AUTOIMMUNITY | PORPHYROMONAS-GINGIVALIS | DISEASE | AUTOANTIGEN | RHEUMATOLOGY | REFRACTORY LYME ARTHRITIS | Humans | Middle Aged | Synovial Fluid - metabolism | Synovial Membrane - immunology | DNA, Ribosomal - metabolism | Male | Th1 Cells - immunology | Organothiophosphorus Compounds - immunology | Young Adult | Tandem Mass Spectrometry | Prevotella - immunology | Immunoglobulin G - immunology | Leukocytes, Mononuclear - immunology | Polymerase Chain Reaction | Aged, 80 and over | Adult | Female | Bacterial Proteins - immunology | Prevotella - genetics | Epitopes, T-Lymphocyte - immunology | DNA, Ribosomal - genetics | Enzyme-Linked Immunosorbent Assay | Peptides - immunology | Enzyme-Linked Immunospot Assay | Arthritis, Rheumatoid - microbiology | Gastrointestinal Microbiome - genetics | Immunoglobulin A - immunology | Aged | Gastrointestinal Microbiome - immunology | Arthritis, Rheumatoid - immunology | Peptides | Pathogenesis | Immunoglobulin G | Helper cells | Antibodies | Lymphocytes T | Arthritis | Assaying | Immunoglobulin A | Subgroups | Proteins | Synovial fluid | Antigenicity | Water analysis | Intestine | Direct reduction | Peripheral blood mononuclear cells | Feces | Digestive tract | Enzyme-linked immunosorbent assay | Deoxyribonucleic acid--DNA | Enzymes | Cytokines | Rheumatic diseases | Mass spectroscopy | Citrulline | Epitopes | Patients | Diseases | Polymerase chain reaction | Rheumatoid arthritis | Histocompatibility antigen HLA | Mass spectrometry
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2017, Volume 127, Issue 8, pp. 2946 - 2956
In rheumatoid arthritis (RA), immunological triggers at mucosal sites, such as the gut microbiota, may promote autoimmunity that affects joints. Here, we used... 
TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | NATURAL AUTOANTIBODIES | B-CELL RESPONSES | VIRUS | PORPHYROMONAS-GINGIVALIS | DISEASE | BACTEROIDES-THETAIOTAOMICRON | MOLECULAR MIMICRY | REFRACTORY LYME ARTHRITIS | HUMAN GUT SYMBIONT | Sulfatases - immunology | Filamins - immunology | Leukocytes, Mononuclear - metabolism | Enzyme-Linked Immunosorbent Assay | Humans | Gastrointestinal Microbiome | Joints - pathology | Synovial Membrane - metabolism | Epitopes - immunology | Arthritis, Rheumatoid - drug therapy | Autoimmunity - immunology | Immunoglobulin G - immunology | Joints - immunology | Autoantigens - immunology | Immunoglobulin A - immunology | Leukocytes, Mononuclear - immunology | Leukocytes, Mononuclear - cytology | HLA-DR Antigens - immunology | Arthritis, Rheumatoid - immunology | Antirheumatic Agents - therapeutic use | Autoantigens | Research | Microbiota (Symbiotic organisms) | T cells | Analysis | Rheumatoid arthritis | N-Acetylglucosamine-6-sulfatase | Mucosal immunity | Disease | Peptides | N-Acetylglucosamine | Mucosa | Leukocytes (mononuclear) | Homology | Lymphocytes T | Cell adhesion & migration | Proteins | Lymphocytes | Peripheral blood mononuclear cells | Antigens | Enzymes | T cell receptors | Citrulline | Epitopes | Joint diseases | Patients | Lymphocytes B | Alleles | Proteomics | Histocompatibility antigen HLA | Autoimmune diseases
Journal Article
Paediatrics and Child Health (Canada), ISSN 1205-7088, 10/2015, Volume 20, Issue 7, pp. 377 - 380
BACKGROUND: Lyme disease is an emerging problem in Nova Scotia. Lyme arthritis is a late manifestation of Lyme disease. OBJECTIVE: To describe the demographic... 
Lyme disease | Pediatrics | Antibiotic refractory | Lyme arthritis | CANADA | DISEASE
Journal Article
Paediatrics & child health, ISSN 1205-7088, 10/2015, Volume 20, Issue 7, pp. 377 - 380
Lyme disease is an emerging problem in Nova Scotia. Lyme arthritis is a late manifestation of Lyme disease. To describe the demographic characteristics,... 
Lyme disease | Pediatrics | Antibiotic refractory | Original | Lyme arthritis
Journal Article
Infection and Immunity, ISSN 0019-9567, 04/2018, Volume 86, Issue 4
Host genotype influences the severity of murine Lyme borreliosis, caused by the spirochetal bacterium Borrelia burgdorferi. C57BL/6 (B6) mice develop mild Lyme... 
Lyme | Borrelia | Macrophages | IL-10 | CELLS | INFECTIOUS DISEASES | RECEPTOR | IMMUNOLOGY | REFRACTORY LYME ARTHRITIS | macrophages | DISEASE | HOST-DEFENSE | MICE | CD14 | INFLAMMATORY RESPONSE | TOLL | EXPRESSION
Journal Article
International journal of medical sciences, ISSN 1449-1907, 2018, Volume 15, Issue 13, pp. 1473 - 1479
In this study, we investigated the mechanisms that lead to the production of proinflammatory mediators by the murine macrophage cell line, RAW264.7, when thes