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Kidney International, ISSN 0085-2538, 04/2019, Volume 95, Issue 4, pp. 797 - 814
Cisplatin is an effective chemotherapeutic agent, but significant nephrotoxicity limits its clinical use. Despite extensive investigation of the acute cellular... 
regulated necrosis | cisplatin CKD | failed repair | PATHWAYS | NECROPTOSIS | INJURY | MECHANISMS | GELATINASE-ASSOCIATED LIPOCALIN | NEPHROPATHY | CELL-DEATH | INFLAMMATION | UROLOGY & NEPHROLOGY | ATUBULAR GLOMERULI | PROGRESSION
Journal Article
Archives of Dermatological Research, ISSN 0340-3696, 7/2011, Volume 303, Issue 5, pp. 351 - 360
Journal Article
Journal of Surgical Research, ISSN 0022-4804, 05/2018, Volume 225, pp. 108 - 117
Journal Article
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, p. e0171157
Glioblastoma is a common malignant brain tumor and it is refractory to therapy because it usually contains a mixture of cell types. The tumor necrosis... 
OVARIAN-CANCER CELLS | BREAST-CANCER | DEATH RECEPTORS | PROTEIN | HUMAN HEPATOMA-CELLS | MULTIDISCIPLINARY SCIENCES | RESISTANCE | PROLIFERATION | MEDIATED APOPTOSIS | UP-REGULATION | EXPRESSION | Glioblastoma - enzymology | Lovastatin - pharmacology | Apoptosis - drug effects | Humans | NF-kappa B - metabolism | Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | TNF-Related Apoptosis-Inducing Ligand - pharmacology | HEK293 Cells | Lovastatin - administration & dosage | Disease Models, Animal | Subcutaneous Tissue - pathology | Lovastatin - therapeutic use | TNF-Related Apoptosis-Inducing Ligand - therapeutic use | Up-Regulation - drug effects | Animals | MAP Kinase Signaling System - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Models, Biological | Glioblastoma - pathology | Cell Line, Tumor | Cell Proliferation - drug effects | Mice, Inbred BALB C | Glioblastoma - drug therapy | Subcutaneous Tissue - drug effects | Brain | Therapy | Biotechnology | Brain tumors | Brain cancer | Glioblastoma | Lovastatin | Neurosurgery | Kinases | Inactivation | Anticancer properties | Proteins | Cell growth | Pathways | Rodents | Surgery | Coinjection | Cell cycle | Tumor necrosis factor-TNF | NF-κB protein | Medical research | Deactivation | Extracellular signal-regulated kinase | MAP kinase | JNK protein | Breast cancer | Injection | Signaling | Tumor necrosis factor | Cell death | Cell lines | Ligands | TRAIL protein | Mice | Glioblastoma cells | In vivo methods and tests | Combined treatment | Apoptosis
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/1998, Volume 18, Issue 5, pp. 1633 - 1641
Journal Article
Molecular Cancer, ISSN 1476-4598, 04/2010, Volume 9, Issue 1, pp. 73 - 73
Background: Tumor necrosis factor alpha (TNF alpha) has been used to treat certain tumors in clinic trials. However, the curative effect of TNF alpha has been... 
APOPTOSIS | PANCREATIC DUCTAL ADENOCARCINOMA | CANCER CELLS | ANGIOGENESIS | ONCOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | REGULATED GENE-PRODUCTS | PROLIFERATION | TNF-ALPHA | EXPRESSION | TRITERPENE
Journal Article
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 11/2013, Volume 13, Issue 11, pp. 2797 - 2804
Transplantation is invariably associated with ischemia–reperfusion injury (IRI), inflammation and rejection. Resultant cell death has morphological features of... 
RIPK1 | RIPK3 | regulated necrosis | necrostatin | Apoptosis | necroptosis | SURGERY | INDUCED SHOCK | MIXED LINEAGE KINASE | PROGRAMMED NECROSIS | CHAIN ASSEMBLY COMPLEX | DOMAIN-LIKE | TRANSPLANTATION | TUMOR-NECROSIS-FACTOR | TNF-INDUCED NECROSIS | LIVER-INJURY | IN-VIVO | NECROTIC CELL-DEATH | Animals | Reperfusion Injury - pathology | Immunity, Cellular | Humans | Necrosis | Physiological aspects | Reperfusion injury | Ischemia | Kinases
Journal Article