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Clinical Immunology, ISSN 1521-6616, 07/2014, Volume 153, Issue 1, pp. 23 - 30
It is hypothesized that CD4 CD25 FoxP3 regulatory T cells (Tregs) can prevent destruction of pancreatic islets protecting from type 1 diabetes (DM1). Here we... 
CD4 + CD25 + T regulatory cells | Tregs | Immunotherapy | Type 1 diabetes mellitus
Journal Article
International Immunology, ISSN 0953-8178, 02/2014, Volume 26, Issue 2, pp. 61 - 69
Journal Article
Microbes and infection, ISSN 1286-4579, 12/2019
Knowledge of the role of Tregs in the immunopathogenesis of the different clinical outcomes within the leprosy spectrum remains limited due to the lack of... 
Journal Article
Transplantation, ISSN 0041-1337, 05/2018, Volume 102, Issue 10, pp. 1597 - 1598
Journal Article
IMMUNITY, ISSN 1074-7613, 04/2008, Volume 28, Issue 4, pp. 546 - 558
The regulatory T (Treg) cells restrain immune responses through suppressor-function elaboration that is dependent upon expression of the transcription factor... 
INTESTINAL INFLAMMATION | MOUSE ASTHMA MODEL | TARGET GENES | TGF-BETA | REGULATORY CELLS | DENDRITIC CELLS | TRANSCRIPTION FACTOR FOXP3 | AIRWAY INFLAMMATION | MEDIATED SUPPRESSION | MICE | IMMUNOLOGY
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 08/2009, Volume 106, Issue 31, pp. 12885 - 12890
The development of T helper (T-H)17 and regulatory T (T-reg) cells is reciprocally regulated by cytokines. Transforming growth factor (TGF)-beta alone induces... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | TGF-BETA | MULTIDISCIPLINARY SCIENCES | RECEPTOR | INTERLEUKIN-9 | CYTOKINE | INDUCTION | regulatory cells | autoimmunity | TRANSCRIPTION FACTOR FOXP3 | GROWTH | STAT5 | GLYCOPROTEIN | tolerance
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 11/2006, Volume 177, Issue 10, pp. 7398 - 7405
In this study, we investigated whether CD4(+)CD25(high) regulatory T cells (Treg) are increased in the tumor tissue and peripheral blood of early-stage... 
IMMUNITY | HEPATOCELLULAR-CARCINOMA | IN-VITRO | REGULATORY CELLS | INFILTRATING LYMPHOCYTES | DEPLETION | IMMUNOLOGY | EXPRESSION | FOXP3 | DRAINING LYMPH-NODES | DISEASE PROGRESSION
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 01/2013, Volume 110, Issue 5, pp. E415 - E424
Each year, more than 700,000 people undergo cancer surgery in the United States. However, more than 40% of those patients develop recurrences and have a poor... 
CELLS | MECHANISM | RESECTION | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | CYTOREDUCTION | INDUCTION | T regulatory cells | tumor macrophages | GROWTH | immunology | ADJUVANT IMMUNOTHERAPY | CARCINOMA | ANTIGEN
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 10/2019, Volume 203, Issue 8, pp. 2150 - 2162
Hepatic immune system is uniquely challenged to mount a controlled effector response to pathogens while maintaining tolerance to diet and microbial Ags. We... 
POPULATION | TCR | ACTIVATION | REGULATORY CELLS | ALPHA-CHAIN | TOLERANCE | INNATE-LIKE FEATURES | RECEPTOR | IMMUNOLOGY | EXPRESSION | BETA
Journal Article
IMMUNITY, ISSN 1074-7613, 08/2007, Volume 27, Issue 2, pp. 334 - 348
gamma delta T cells are important contributors to innate immunity against cancer, but their regulatory role in controlling immune responses remains largely... 
REGULATORY-CELLS | LUNG-CANCER | RECOGNITION | KINASE TAK1 | IMMUNOTHERAPY | IMMUNE-RESPONSES | PERIPHERAL-BLOOD | IMMUNOLOGY | INNATE IMMUNITY | ANTIGEN | LYMPHOCYTES
Journal Article
Proceedings of the Nutrition Society, ISSN 0029-6651, 05/2012, Volume 71, Issue 2, pp. 316 - 321
Journal Article
NATURE REVIEWS RHEUMATOLOGY, ISSN 1759-4790, 09/2014, Volume 10, Issue 9, pp. 543 - 551
Naturally occurring Foxp3(+)CD25(+)CD4(+) regulatory T (T-REG) cells maintain immunological self-tolerance and prevent a variety of autoimmune diseases,... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | TGF-BETA | REGULATORY CELLS | SYNOVIAL-FLUID | JUVENILE IDIOPATHIC ARTHRITIS | TRANSCRIPTION FACTOR FOXP3 | RETINOIC-ACID | IN-VIVO | IMMUNOLOGICAL SELF-TOLERANCE | RHEUMATOLOGY | EFFECTOR-CELLS
Journal Article
Cancer Research, ISSN 0008-5472, 07/2012, Volume 72, Issue 13, pp. 3125 - 3130
Established tumors are complex masses that contain not only neoplastic cells but also nontransformed cellular elements such as stromal cells, the... 
INHIBITION | COLONY-STIMULATING FACTOR | DENDRITIC CELLS | ONCOLOGY | T-REGULATORY CELLS | INFLAMMATION | MACROPHAGES | SUPPRESSOR-CELLS | CANCER-IMMUNOTHERAPY | MYELOID CELLS | LYMPHOCYTES | Neoplasms - therapy | Tumor Escape | Interleukin-12 - genetics | Neoplasms - immunology | Humans | Immunotherapy | Tumor Microenvironment | Macrophage Activation
Journal Article
Science Signaling, ISSN 1945-0877, 01/2017, Volume 10, Issue 462
Major barriers to cancer therapy include the lack of selective inhibitors of regulatory T cells (T-regs) and the lack of broadly applicable ways to directly... 
REGULATORY-CELLS | APO2L/TRAIL | NECROSIS-FACTOR RECEPTOR | COMPLEX | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMORADIOTHERAPY | PERIPHERAL-BLOOD | INDUCTION | EXPRESSION | FACTOR-ALPHA | CELL BIOLOGY
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 07/2018, Volume 201, Issue 2, pp. 772 - 781
Leukocyte-associated Ig-like receptor 1 (LAIR1) is an ITIM-bearing collagen receptor expressed by leukocytes and is implicated in immune suppression. However,... 
COLLAGEN TYPE-V | ACTIVATION | LAIR-1 | MECHANISM | T-REGULATORY CELLS | AUTOIMMUNITY | MICE | DIFFERENTIATION | IMMUNOLOGY | OBLITERATIVE BRONCHIOLITIS | TRANSPLANTATION
Journal Article