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Organic Letters, ISSN 1523-7060, 11/2017, Volume 19, Issue 21, pp. 5912 - 5915
A new submonomeric synthetic method of β-peptoids that allows introduction of chiral backbone substituents is established. The synthesis of β-peptoids with... 
SIDE-CHAINS | PEPTIDOMIMETICS | CIRCULAR-DICHROISM | PEPTIDES | CHIMERAS | COMBINATORIAL LIBRARIES | FOLDAMERS | CHEMISTRY, ORGANIC | RELATIVE CELL-PERMEABILITY | OLIGOMERS | DISCOVERY
Journal Article
BIOPOLYMERS, ISSN 0006-3525, 06/2019, Volume 110, Issue 6
Peptoids, oligomers of N-substituted glycines, have been attracting increasing interest due to their advantageous properties as peptidomimetics. However, due... 
SUBSTITUTION | DESIGN | peptoid | alpha-ABpeptoid | CYCLIC PEPTOIDS | HELICAL FOLDAMERS | PEPTIDE | BIOPHYSICS | alpha-ABpeptoid/beta-peptide hybrid | peptidomimetics | RELATIVE CELL-PERMEABILITY | CHAIN-LENGTH | foldamer
Journal Article
by Lee, KJ and Lee, WS and Yun, H and Hyun, YJ and Seo, CD and Lee, CW and Lim, HS
ORGANIC LETTERS, ISSN 1523-7060, 08/2016, Volume 18, Issue 15, pp. 3678 - 3681
A new class of peptoid-based peptidomimetics composed of oligomers of N-substituted beta(2)-homoalanines is reported. Design, solid-phase synthesis, and... 
AROMATIC SIDE-CHAINS | CIRCULAR-DICHROISM | SOLID-PHASE SYNTHESIS | COMBINATORIAL LIBRARIES | FOLDAMERS | CYCLIC PEPTOIDS | CHEMISTRY, ORGANIC | SECONDARY STRUCTURE | BETA-PEPTOIDS | RELATIVE CELL-PERMEABILITY | ALPHA-PEPTOIDS
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2011, Volume 133, Issue 39, pp. 15559 - 15567
Journal Article
Chemical Science, ISSN 2041-6520, 2014, Volume 5, Issue 3, pp. 887 - 893
N-Alkyl amino acids are invaluable building blocks for ribosomally synthesized peptides because they can increase proteolytic stability and cell-permeability... 
GENETIC-CODE | DISPLAY | SPECIFICITY | ASPARTIC-ACID | PEPTOIDS | IN-VITRO SELECTION | RELATIVE CELL-PERMEABILITY | TRANSLATION | PROTEINS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Organic Letters, ISSN 1523-7060, 10/2011, Volume 13, Issue 19, pp. 5012 - 5015
Triazine-bridged bicyclic peptoids as conformationally constrained peptidomimetics are described. Bicyclic peptoids composed of 6–12 peptoid residues (m, n =... 
PEPTIDES | MACROCYCLES | COMBINATORIAL LIBRARIES | DRUG DISCOVERY | CHEMISTRY, ORGANIC | PROTEIN-PROTEIN INTERACTIONS | RELATIVE CELL-PERMEABILITY | STRATEGIES | Bridged Bicyclo Compounds, Heterocyclic - chemistry | Molecular Structure | Peptoids - chemical synthesis
Journal Article
BIOCONJUGATE CHEMISTRY, ISSN 1043-1802, 05/2012, Volume 23, Issue 5, pp. 1069 - 1079
Peptoids are a rapidly developing class of biomimetic polymers based on oligo-N-substituted glycine backbones, designed to mimic peptides and proteins.... 
MAGAININ-2 | MECHANISM | MIMICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | PEXIGANAN | POLYPEPTOIDS | CHEMISTRY, MULTIDISCIPLINARY | OLIGOMERS | HOST-DEFENSE PEPTIDES | SIDE-CHAINS | N-SUBSTITUTED GLYCINES | RELATIVE CELL-PERMEABILITY
Journal Article
ChemPlusChem, ISSN 2192-6506, 01/2014, Volume 79, Issue 1, pp. 25 - 30
Cyclic peptoids are potential candidates for diverse biological activities. However, applications of cyclic peptoids are limited by the synthetic difficulties,... 
autophagy | peptoids | cyclization | hydrogen bonds | synthetic methods | PEPTIDES | RELATIVE CELL-PERMEABILITY | CHEMISTRY, MULTIDISCIPLINARY | CYCLIZATION | DISCOVERY | Glycine | Hydrogen | Analysis
Journal Article
Biomaterials Science, ISSN 2047-4830, 2014, Volume 2, Issue 5, pp. 627 - 633
Poly(N-substituted glycine) "peptoids" have conventionally been exploited for drug discovery and therapeutics due to their structural similarity to peptides,... 
POLYMERS | AMINO-ACID | MATERIALS SCIENCE, BIOMATERIALS | PROTEIN ADSORPTION | SOLID-PHASE SYNTHESIS | DRUG DISCOVERY | IN-VIVO | N-CARBOXYANHYDRIDES | RELATIVE CELL-PERMEABILITY | OLIGOMERS | MEDIATED ZWITTERIONIC POLYMERIZATION
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4396 - 10
Journal Article
European Journal of Lipid Science and Technology, ISSN 1438-7697, 04/2018, Volume 120, Issue 4, pp. 1700317 - n/a
In order to enhance the lipophilicity and thus oral bioavailability of icariin (ICA) and icariside II (ICA II) of total flavonoids of epimedium (TFE), a total... 
nanosuspensions | relative bioavailability | ICA and ICA II | characterization | phospholipid complex | NUTRITION & DIETETICS | ICARISIDE II | DRUG-DELIVERY | FOOD SCIENCE & TECHNOLOGY | Flavonoids | Phospholipids | Flavones | Bioflavonoids | Lipophilic | Wettability | Cell permeability | Octanol | Human exposure | Oral administration | Bioavailability | Dispersion | Lipophilicity
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 09/2014, Volume 2014, Issue 26, pp. 5641 - 5657
This review covers the published literature describing the synthesis of glycopeptoids, a family of glycopeptide mimics. Members of this family are composed of... 
Glycopeptidomimetics | Glycoclusters | Multivalency | Glycoconjugates | Peptidomimetics | Ligands | Peptoids | CROSS-METATHESIS | SOLID-PHASE SYNTHESIS | GLYCOSYLATED PEPTOIDS | SIDE-CHAIN | CHEMISTRY, ORGANIC | VERSATILE APPROACH | SUGAR AMINO-ACIDS | BETA-ALANINE | RELATIVE CELL-PERMEABILITY | ALPHA-PEPTOIDS | RATIONAL DESIGN | Biomimetics | Nitrogen | Glycine | Chemical Sciences
Journal Article