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Journal of Immunological Methods, ISSN 0022-1759, 09/2015, Volume 424, pp. 43 - 52
The therapeutic monoclonal antibody (mAb) TGN1412 (anti-CD28 superagonist) caused near-fatal cytokine release syndrome (CRS) in all six volunteers during a... 
Whole blood | Group size | TGN1412 | Cytokine release assay | PBMC | Therapeutic mAb | REVEALS WORRYING DIFFERENCES | BIOCHEMICAL RESEARCH METHODS | MONOCLONAL-ANTIBODY TGN1412 | IMMUNOLOGY | VITRO ASSAYS | FC-GAMMA-RIIB | T-CELL RESPONSES | MULTIPLE-SCLEROSIS | RITUXIMAB | CD28 | CHRONIC LYMPHOCYTIC-LEUKEMIA | SYNDROME IN-VIVO | Antibodies, Monoclonal, Humanized - adverse effects | Leukocytes, Mononuclear - metabolism | Glycophorin - metabolism | Antibodies, Monoclonal, Humanized - therapeutic use | Leukocytes, Mononuclear - drug effects | Cytokines - metabolism | Humans | Immunoglobulin G - therapeutic use | Antineoplastic Agents - therapeutic use | Alemtuzumab | Daclizumab | Fluoroimmunoassay - methods | Antibodies, Monoclonal - administration & dosage | Antineoplastic Agents - adverse effects | Antibodies, Monoclonal, Humanized - pharmacology | Erythrocytes - metabolism | Immunoglobulin G - pharmacology | Cytokines - blood | Cytokines | Monoclonal antibodies | Health aspects | GYPA, glycophorin A | mAb, monoclonal antibody | WBC, white blood cells | IFNγ, interferon gamma | TNFα, tumor necrosis factor alpha | HDC, high density culture | SP, Solid Phase | RBCs, Red Blood Cells | PBMCs, peripheral blood mononuclear cells | CRS, cytokine release syndrome | IL-2, interleukin-2 | AQ, Aqueous Phase | WB, whole blood | PBS, phosphate buffered saline | IL-8, interleukin-8 | IL-13, interleukin-13 | CRA, cytokine release assay | IL-2R, interleukin-2 receptor | IL-17, interleukin-17 | TCR, T cell receptor
Journal Article
Journal Article
Journal Article
Annals of the American Thoracic Society, ISSN 2325-6621, 10/2014, Volume 11, Issue 8, pp. 1267 - 1276
Interferon gamma (IFN-γ) release assays for latent tuberculosis infection result in a larger-than-expected number of conversions and reversions in occupational... 
Tuberculosis | Diagnostics | Reproducibility | IFN-γ release assays | Tuberculosis - immunology | Reproducibility of Results | Humans | Interferon-gamma - immunology | Tuberculin - immunology | Tuberculosis - blood | Tuberculosis - diagnosis | Interferon-gamma - blood
Journal Article
Tuberculosis, ISSN 1472-9792, 2012, Volume 92, Issue 4, pp. 321 - 327
Journal Article