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Biochemical Pharmacology, ISSN 0006-2952, 11/2019, Volume 169, p. 113608
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are used for many applications including safety pharmacology. However, a deficiency or... 
Repolarization reserve | Electrophysiology | Action potential | Extracellular field potential | NS3623
Journal Article
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 09/2009, Volume 297, Issue 3, pp. 1048 - 1057
Reduction of repolarization reserve increases the risk of arrhythmia. We hypothesized that inhibition of K+ current (IK) to decrease repolarization reserve... 
Repolarization reserve | Ion currents | Monophasic action potential | Ventricular tachycardia | Late sodium current | TORSADES-DE-POINTES | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | CARDIAC PURKINJE-FIBERS | K+ CURRENT | repolarization reserve | LONG-QT SYNDROME | VENTRICULAR MYOCYTES | late sodium current | IN-VITRO | monophasic action potential | ventricular tachycardia | RANOLAZINE | TRANSMURAL DISPERSION | PERIPHERAL VASCULAR DISEASE | CHANNELS | ion currents | Anti-Arrhythmia Agents - pharmacology | Humans | Sodium Channels - physiology | Sodium - metabolism | ERG1 Potassium Channel | Ranolazine | Piperidines - pharmacology | Heart Conduction System - physiology | Female | Ether-A-Go-Go Potassium Channels - physiology | Tetrodotoxin - pharmacology | Torsades de Pointes - physiopathology | 4-Aminopyridine - pharmacology | Action Potentials - drug effects | Potassium Channel Blockers - pharmacology | Cell Line | Rabbits | Acetanilides - pharmacology | Chlorides - pharmacology | Enzyme Inhibitors - pharmacology | Sodium Channel Blockers - pharmacology | Kidney - cytology | Piperazines - pharmacology | Barium Compounds - pharmacology | Action Potentials - physiology | Ether-A-Go-Go Potassium Channels - antagonists & inhibitors | Patch-Clamp Techniques | Tachycardia, Ventricular - physiopathology | Animals | Pyridines - pharmacology | Index Medicus
Journal Article
Cardiovascular Research, ISSN 0008-6363, 02/2007, Volume 73, Issue 3, pp. 512 - 520
Journal Article