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Annals of Oncology, ISSN 0923-7534, 06/2013, Volume 24, Issue 6, pp. 1513 - 1525
Background: To assess the impact of single-nucleotide polymorphisms (SNPs) on predefined severe adverse events in breast cancer (BC) patients receiving... 
ABCC1 | MRP1 | Single-nucleotide polymorphisms | Breast cancer | FEC chemotherapy | Febrile neutropenia | ADJUVANT CHEMOTHERAPY | COLONY-STIMULATING FACTOR | EORTC GUIDELINES | aBCC1 | DIHYDROPYRIMIDINE DEHYDROGENASE | breast cancer | INDUCED FEBRILE NEUTROPENIA | febrile neutropenia | DEHYDROGENASE DPD DEFICIENCY | DRUG-METABOLIZING-ENZYMES | mRP1 | ONCOLOGY | COLORECTAL-CANCER | ANTHRACYCLINE-INDUCED CARDIOTOXICITY | fEC chemotherapy | GLUTATHIONE-S-TRANSFERASE | single-nucleotide polymorphisms | Predictive Value of Tests | Cyclophosphamide - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Follow-Up Studies | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Epirubicin - administration & dosage | Cyclophosphamide - adverse effects | Fluorouracil - administration & dosage | Fluorouracil - adverse effects | Chemotherapy, Adjuvant - adverse effects | Adult | Female | Multidrug Resistance-Associated Proteins - genetics | Retrospective Studies | Hematologic Diseases - chemically induced | Breast Neoplasms - drug therapy | Hematologic Diseases - diagnosis | Breast Neoplasms - genetics | Neoadjuvant Therapy - adverse effects | Hematologic Diseases - genetics | Polymorphism, Single Nucleotide - genetics | Genetic Variation - genetics | Epirubicin - adverse effects | Index Medicus | 5-Fluorouracil
Journal Article
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 06/2017, Volume 18, Issue 6, p. 1178
Phytochemicals are natural compounds synthesized as secondary metabolites in plants, representing an important source of molecules with a wide range of... 
MiRNAs | Phytochemicals | Coding and non-coding RNA | Apoptosis | Cancer | coding and non-coding RNA | EPIGALLOCATECHIN GALLATE EGCG | miRNAs | KAEMPFEROL-INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACID PHENETHYL ESTER | apoptosis | MITOCHONDRIA-DEPENDENT PATHWAY | phytochemicals | CELL-CYCLE ARREST | GENISTEIN INDUCES APOPTOSIS | HUMAN BREAST-CANCER | CHEMISTRY, MULTIDISCIPLINARY | DOWN-REGULATES ONCO-MIR-1260B | RESISTANCE PROTEIN-1 ABCC1 | LEUKEMIA HL-60 CELLS | cancer | Neoplasms - metabolism | Phytochemicals - therapeutic use | Antioxidants - chemistry | Apoptosis - drug effects | Humans | Polyphenols - pharmacology | Apoptosis - genetics | Structure-Activity Relationship | Neoplasms - genetics | Gene Expression Regulation, Neoplastic - drug effects | Antineoplastic Agents, Phytogenic - therapeutic use | Drug Evaluation, Preclinical | Phytochemicals - chemistry | RNA, Untranslated | Antineoplastic Agents, Phytogenic - chemistry | Antioxidants - pharmacology | Neoplasms - drug therapy | Antioxidants - therapeutic use | Drug Resistance, Neoplasm - genetics | Animals | Polyphenols - chemistry | Polyphenols - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacology | Neoplasms - pathology | Dietary Supplements | Phytochemicals - pharmacology | RNA, Messenger | Drug Resistance, Neoplasm - drug effects
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 11/2010, Volume 99, Issue 11, pp. 4630 - 4641
The aim of this study was to evaluate the effect of curcumin (CUR) in oral bioavailability and therapeutic efficacy of paclitaxel (PTX) administered in... 
oil-in-water nanoemulsion | oral bioavailability | paclitaxel/curcumin co-therapy | therapeutic efficacy | ovarian adenocarcinoma | oil‐in‐water nanoemulsion | paclitaxel/curcumin co‐therapy | Therapeutic efficacy | Oral bioavailability | Paclitaxel/curcumin co-therapy | Ovarian adenocarcinoma | Oil-in-water nanoemulsion | CHEMISTRY, MEDICINAL | TURMERIC POWDER | DRUG-DELIVERY | MULTIFUNCTIONAL NANOCARRIERS | FACTOR-KAPPA-B | TUMOR-CELLS | CANCER | CHEMISTRY, MULTIDISCIPLINARY | P-GLYCOPROTEIN ABCB1 | RESISTANCE PROTEIN-1 ABCC1 | DEOXYCHOLIC-ACID | PHARMACOLOGY & PHARMACY | MULTIDRUG-RESISTANCE | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Paclitaxel - pharmacology | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Biological Availability | Paclitaxel - pharmacokinetics | Curcumin - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Enzyme Inhibitors - administration & dosage | Antineoplastic Agents, Phytogenic - administration & dosage | Female | Antineoplastic Agents, Phytogenic - therapeutic use | Paclitaxel - administration & dosage | Antineoplastic Agents, Phytogenic - pharmacokinetics | Ovarian Neoplasms - drug therapy | Emulsions - chemistry | Curcumin - pharmacology | Enzyme Inhibitors - pharmacology | Adenocarcinoma - drug therapy | Paclitaxel - therapeutic use | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cytochrome P-450 CYP3A - metabolism | Mice | Antineoplastic Agents, Phytogenic - pharmacology | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e32920
Retinoblastoma is the most common intraocular tumor in children. Malfunctioning of many signaling pathways regulating cell survival or apoptosis, make the... 
APOPTOSIS | ANTAGONIST NUTLIN-3 | RETINOBLASTOMA CELLS | TURMERIC POWDER | IN-VIVO | BIOLOGY | CELL-CYCLE ARREST | P53 PATHWAY | P-GLYCOPROTEIN ABCB1 | CANCER-THERAPY | PROTEIN-1 ABCC1 | Lactic Acid - chemistry | Nanoparticles - chemistry | Apoptosis - drug effects | Humans | Retinoblastoma - drug therapy | Curcumin - pharmacology | Folic Acid - chemistry | Gene Expression Regulation, Neoplastic | Tumor Suppressor Protein p53 - metabolism | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | NF-kappa B - metabolism | Imidazoles - pharmacology | Membrane Potential, Mitochondrial - drug effects | Piperazines - pharmacology | Drug Carriers - chemistry | Proto-Oncogene Proteins c-bcl-2 - metabolism | Cell Cycle Checkpoints | NF-kappa B - genetics | Polyglycolic Acid - chemistry | Cell Line, Tumor | Multidrug Resistance-Associated Proteins - genetics | Multidrug Resistance-Associated Proteins - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Drug Resistance, Neoplasm - drug effects | Drug resistance in microorganisms | Chemotherapy | Analysis | Disease susceptibility | Tumor proteins | Folic acid | Apoptosis | Cancer | Cytochrome | Drugs | Toxicity | Material requirements planning | Genotoxicity | Reversing | Cytotoxicity | Drug resistance | Kinases | Autophagy | Cancer therapies | Polylactide-co-glycolide | Nanoparticles | Proteins | Disease resistance | Vitamin B | Cell cycle | Gangrene | Life sciences | Curcumin | Children | MRP1 protein | Cell survival | Multidrug resistance | Bioavailability | Permeability | Gene expression | Magnetohydrodynamic stability | Signaling | Lungs | Tumor suppressor genes | Retinoblastoma | Tumors
Journal Article
Journal Article