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Toxicology and Applied Pharmacology, ISSN 0041-008X, 12/2012, Volume 265, Issue 3, pp. 351 - 359
Clobazam (CLB) is known to increase hepatobiliary thyroxine (T4) clearance in Sprague–Dawley (SD) rats, which results in hypothyroidism followed by thyroid... 
MRP2 | Thyroid cellular hypertrophy | TSH | Hypothyroidism | Clobazam | Efflux transporter | Microsomal enzyme inducer | Thyroid-stimulating hormone | Thyroxine | Triiodothyronine | EHBR rats | UGT1A | UGT2B | Gunn rats | PROPYLTHIOURACIL | INDUCTION | METABOLISM | PHARMACOLOGY & PHARMACY | TOXICOLOGY | MICROSOMAL-ENZYME INDUCERS | MECHANISM | IODIDE | PREGNANE-X-RECEPTOR | GUNN-RATS | HORMONE | LIVER | Gene Expression - drug effects | Male | Multidrug Resistance-Associated Proteins - biosynthesis | Thyroid Gland - enzymology | Anticonvulsants - pharmacology | Glucuronosyltransferase - genetics | RNA, Messenger - biosynthesis | Isoenzymes - metabolism | Thyroid Hormones - blood | Multidrug Resistance-Associated Proteins - genetics | Real-Time Polymerase Chain Reaction | Thyroid Gland - drug effects | Benzodiazepines - pharmacology | Isoenzymes - genetics | RNA, Messenger - genetics | Rats | Random Allocation | Rats, Sprague-Dawley | Animals | Rats, Gunn | Glucuronosyltransferase - metabolism | Thyroid Gland - pathology | Thyroid Hormones - metabolism | Histocytochemistry | Isoenzymes - biosynthesis | Thyroid Gland - metabolism | Glucuronosyltransferase - biosynthesis | Multidrug Resistance-Associated Proteins - metabolism | Hypertrophy | Index Medicus | Isoenzymes | Liver | mRNA | Thyroid hormones | Thyroid | TRIIODOTHYRONINE | RATS | THYROID | THYROXINE | PATHOLOGY | 60 APPLIED LIFE SCIENCES | ISOENZYMES | MORPHOLOGICAL CHANGES | HYPOTHYROIDISM | HYPERTROPHY | MUTANTS | MESSENGER-RNA | ENZYMES | GENES | MORPHOLOGY
Journal Article
Biochimie, ISSN 0300-9084, 10/2019, Volume 165, pp. 179 - 182
Journal Article
DRUG METABOLISM AND DISPOSITION, ISSN 0090-9556, 05/2018, Volume 46, Issue 5, pp. 610 - 618
The purpose of the present study was to clarify the molecular basis of zonated drug distributions in mouse liver based on the protein expression levels of... 
RAT-LIVER | PEPTIDE SELECTION | HETEROGENEITY | HEPATOCYTES | BILIARY-EXCRETION | IN-VITRO SYSTEMS | PHARMACOLOGY & PHARMACY | TARGETED ABSOLUTE PROTEOMICS | RESISTANCE-ASSOCIATED PROTEIN-2 | BILE | POLYPEPTIDE
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 05/2018, Volume 46, Issue 5, pp. 697 - 703
Hepatic drug transporters play a pivotal role in the excretion of drugs from the body, in drug-drug interactions, as well as in drug-induced liver toxicity.... 
ABCC2 MRP2 | EFFLUX | BILIARY-EXCRETION | CANALICULAR NETWORKS | DRUG DISPOSITION | PHARMACOLOGY & PHARMACY | RESISTANCE-ASSOCIATED PROTEIN-2 | HEPATOBILIARY TRANSPORTER | CELL-LINES | SANDWICH-CULTURED RAT | P-GLYCOPROTEIN | Index Medicus
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 06/2014, Volume 57, Issue 1, pp. 99 - 151
Journal Article