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by Zhang, Q and Shi, J and Deng, G and Guo, J and Zeng, X and He, X and Kong, H and Gu, C and Li, X and Liu, J and Wang, G and Chen, Y and Liu, L and Liang, L and Li, Y and Fan, J and Wang, J and Li, W and Guan, L and Li, Q and Yang, H and Chen, P and Jiang, L and Guan, Y and Xin, X and Jiang, Y and Tian, G and Wang, X and Qiao, C and Li, C and Bu, Z and Chen, H
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2013, Volume 341, Issue 6144, pp. 410 - 414
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2012, Volume 336, Issue 6088, pp. 1541 - 1547
Avian A/H5N1 influenza viruses pose a pandemic threat. As few as five amino acid substitutions, or four with reassortaient, might be sufficient for mammal-to-mammal transmission through respiratory droplets... 
Disease transmission | Surveillance | Virions | REPORTS | Viruses | Orthomyxoviridae | Infections | Nucleotides | Genetic mutation | Sequencing | Amino acid substitution | DYNAMICS | H5N1 | REPLICATION | MODEL | A VIRUSES | MULTIDISCIPLINARY SCIENCES | Adaptation, Physiological | Receptors, Virus - metabolism | Air Microbiology | Humans | Influenza A Virus, H5N1 Subtype - genetics | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Respiratory System - virology | Influenza, Human - virology | RNA Replicase - genetics | Selection, Genetic | Sialic Acids - metabolism | Probability | Viral Proteins - genetics | Birds | Glycosylation | Influenza, Human - transmission | Mammals | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Animals | Genetic Fitness | Orthomyxoviridae Infections - transmission | Models, Biological | Influenza in Birds - virology | Influenza A Virus, H5N1 Subtype - pathogenicity | High-Throughput Nucleotide Sequencing | Mutation | Orthomyxoviridae Infections - virology | Amino Acid Substitution | Evolution, Molecular | Influenza, Human - immunology | Avian influenza | Physiological aspects | Development and progression | Research | Epidemiology | Amino acids | Evolution | Avian flu | Influenza | Circulating | Mathematical models | Droplets
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 486, Issue 7403, pp. 420 - 428
.... We identified a reassortant H5 HA/H1N1 virus-comprising H5 HA (from an H5N1 virus) with four mutations and the remaining seven gene segments from a 2009 pandemic H1N1 virus-that was capable of droplet transmission in a ferret model... 
SINGLE AMINO-ACID | MEMBRANE-FUSION | IN-VITRO | AVIAN H5N1 | HEMAGGLUTININ | A VIRUSES | MULTIDISCIPLINARY SCIENCES | SIALIC-ACID | RECEPTOR-BINDING SPECIFICITY | MOLECULAR-BASIS | SWINE-ORIGIN H1N1 | Pandemics | Reassortant Viruses - pathogenicity | Influenza A Virus, H5N1 Subtype - physiology | Receptors, Virus - metabolism | Humans | Influenza A Virus, H1N1 Subtype - physiology | Reassortant Viruses - genetics | Reassortant Viruses - physiology | Influenza A Virus, H5N1 Subtype - genetics | Body Fluids - virology | Molecular Epidemiology - methods | Ferrets - virology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Zoonoses - virology | Respiratory System - virology | Adaptation, Physiological - genetics | HEK293 Cells | Female | Influenza, Human - virology | Protein Stability | Influenza A Virus, H1N1 Subtype - genetics | Population Surveillance - methods | Cell Line | Security Measures | Birds - virology | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza in Birds - transmission | Hot Temperature | Influenza, Human - transmission | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Reassortant Viruses - isolation & purification | Respiratory System - anatomy & histology | Zoonoses - transmission | Animals | Receptors, Virus - chemistry | Orthomyxoviridae Infections - transmission | Dogs | Influenza in Birds - virology | Bioterrorism - prevention & control | Influenza A Virus, H5N1 Subtype - pathogenicity | HeLa Cells | Influenza, Human - prevention & control | Orthomyxoviridae Infections - virology | Evolution, Molecular | Prevention | Epidemics | Disease transmission | United States | Japan | Avian influenza viruses | Physiological aspects | Genetic aspects | Research | Host-virus relationships | Ferrets | Cell culture | Task forces | Compliance | Laboratories | RNA polymerase | Academic libraries | Experiments | Avian flu | Proteins | Studies | Swine flu | Plasmids | Risk assessment | Occupational health | Mutation
Journal Article
Current Opinion in Infectious Diseases, ISSN 0951-7375, 08/2019, Volume 32, Issue 4, pp. 372 - 379
PURPOSE OF REVIEWHealth agencies recommend transmission-based precautions, including contact, droplet and airborne precautions, to mitigate transmission of respiratory viruses in healthcare settings... 
MERS-COV OUTBREAK | INFECTIOUS DISEASES | HEALTH-CARE WORKERS | droplet | PERFORMANCE | infection control | respiratory viruses | N95 RESPIRATORS | SURGICAL MASKS | SOUTH-KOREA | healthcare settings | MEASLES OUTBREAK | PARTICLE-SIZE | INFLUENZA-VIRUS | SYNCYTIAL VIRUS | aerosol | Respiratory tract infections | Virus diseases | Prevention | Airborne infection | Disease transmission | Distribution
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2011, Volume 108, Issue 34, pp. 14264 - 14269
.... To identify molecular determinants that allowed efficient transmission of the pandemic H1N1 virus among humans, we evaluated the direct-contact and respiratory-droplet transmissibility in ferrets... 
H1N1 subtype influenza A virus | Polysaccharides | Receptors | Pandemics | Disease transmission | Influenza A virus | Swine | Viruses | Orthomyxoviridae | Transmission efficiency | Influenza A | Viral genes | Zoonosis | PIGS | PB2 | influenza A | viral genes | SPECIFICITY | MULTIDISCIPLINARY SCIENCES | POLYMERASE | HUMANS | zoonosis | A VIRUS | PATHOGENESIS | SWINE INFLUENZA | REASSORTMENT | Respiratory System - pathology | Tropism | Receptors, Virus - metabolism | Genome, Viral - genetics | Influenza A Virus, H1N1 Subtype - physiology | Neuraminidase - metabolism | Substrate Specificity | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Ferrets - virology | Polysaccharides - metabolism | Orthomyxoviridae Infections - epidemiology | Respiratory System - virology | Animals | Orthomyxoviridae Infections - transmission | Influenza A Virus, H1N1 Subtype - enzymology | Protein Binding | Recombination, Genetic - genetics | Kinetics | Seasons | Influenza A Virus, H1N1 Subtype - genetics | Orthomyxoviridae Infections - virology | Virus Replication - physiology | Influenza viruses | Swine influenza | Erythrocytes | Physiological aspects | Development and progression | Genetic aspects | Ferrets | Health aspects | Life Sciences | Microbiology and Parasitology | Virology | Biological Sciences
Journal Article
by Zhang, Y and Zhang, Q and Kong, H and Jiang, Y and Gao, Y and Deng, G and Shi, J and Tian, G and Liu, L and Liu, J and Guan, Y and Bu, Z and Chen, H
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2013, Volume 340, Issue 6139, pp. 1459 - 1463
In the past, avian influenza viruses have crossed species barriers to trigger human pandemics by reassorting with mammal-infective viruses in intermediate... 
Disease transmission | Guinea pigs | Virulence | REPORTS | Data transmission | Viruses | Orthomyxoviridae | Mice | H5N1 subtype influenza A virus | Ferrets | Transmission efficiency | MAMMALIAN HOST | ORIGIN | INFLUENZA-A VIRUS | AVIAN FLU TRANSMISSION | HEMAGGLUTININ | H1N1 2009 VIRUS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | HUMANS | FERRETS | RECEPTOR SPECIFICITY | Reassortant Viruses - pathogenicity | Receptors, Virus - metabolism | Humans | Brain - virology | Molecular Sequence Data | Reassortant Viruses - genetics | Influenza A Virus, H5N1 Subtype - genetics | Viral Proteins - metabolism | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Respiratory System - virology | Genes, Viral | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Amino Acid Sequence | Cell Line | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Reverse Genetics | Guinea Pigs | Receptors, Cell Surface - metabolism | Viral Proteins - genetics | Influenza A Virus, H1N1 Subtype - pathogenicity | Ribonucleoproteins - metabolism | Influenza, Human - transmission | Animals | Orthomyxoviridae Infections - transmission | Virus Replication | Influenza A Virus, H5N1 Subtype - pathogenicity | Mice, Inbred BALB C | Mutation | Orthomyxoviridae Infections - virology | Avian influenza | Viral genetics | Physiological aspects | Host-parasite relationships | Genetic aspects | Research | Epidemics | Neurons | Avian flu | Genes | Respiratory diseases
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 7, p. e67631
Journal Article
The oncologist (Dayton, Ohio), ISSN 1549-490X, 2016, Volume 21, Issue 2, pp. 156 - 164
Journal Article
Journal Article
Thorax, ISSN 0040-6376, 01/2019, Volume 74, Issue 1, pp. 87 - 90
.... We conclude that Gram-negative bacteria and Staphylococcus aureus are aerosolised during coughing, can travel up to 4 m and remain viable within droplet nuclei for up to 45 min... 
cystic fibrosis | infection control | STRAINS | IDENTIFICATION | RESPIRATORY SYSTEM | PSEUDOMONAS-AERUGINOSA | Studies | Pathogens | Meetings | Editors | Aerosols | Cystic fibrosis | Bacteria | Staphylococcus infections | Organisms | Thorax | Gram-negative bacteria | Experiments
Journal Article