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Journal of Molecular Biology, ISSN 0022-2836, 10/2018, Volume 430, Issue 21, pp. 3892 - 3905
The oxidative phosphorylation system contains four respiratory chain complexes that connect the transport of electrons to oxygen with the establishment of an... 
complex III | mitochondrial gene expression | mitochondria | respiratory chain | assembly factors
Journal Article
Chemosphere, ISSN 0045-6535, 01/2020, Volume 238, p. 124607
A fluoride exposure mouse model is established to evaluate the relationship between mitochondrial respiratory chain complexes and renal dysfunction.... 
Mitochondrial fusion | Fluoride | Respiratory chain complexes | Kidney
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 10/2019
Journal Article
CELL METABOLISM, ISSN 1550-4131, 11/2016, Volume 24, Issue 5, pp. 716 - 727
Metformin use is associated with reduced cancer mortality, but how metformin impacts cancer outcomes is controversial. Although metformin can act on cells... 
DIABETIC-PATIENTS | BREAST-CANCER | RESPIRATORY-CHAIN | LUNG-CANCER | INHIBITION | METABOLISM | PHARMACOKINETICS | PROSTATE-CANCER | ENDOCRINOLOGY & METABOLISM | BIGUANIDES | TUMORIGENESIS | CELL BIOLOGY
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 12/2019, Volume 61, p. 104640
Neuroblastoma is an aggressive form of cancer with high mortality. Hydroxychalcones have received considerable attention because of their cytotoxic activities... 
SH-SY5Y | Mitochondria | Respiratory chain | Hydroxychalcones
Journal Article
SCIENCE TRANSLATIONAL MEDICINE, ISSN 1946-6234, 01/2012, Volume 4, Issue 118
Advances in next-generation sequencing (NGS) promise to facilitate diagnosis of inherited disorders. Although in research settings NGS has pinpointed causal... 
ENCEPHALOPATHY | MEDICINE, RESEARCH & EXPERIMENTAL | HIGH-THROUGHPUT | GENETICS | DNA | DOMINANT | CAPTURE | MUTATION DATABASE | ENCODED SUBUNIT | RESPIRATORY-CHAIN DISORDERS | GENOME BROWSER | CELL BIOLOGY
Journal Article
MOLECULAR AND CELLULAR BIOLOGY, ISSN 0270-7306, 04/2012, Volume 32, Issue 8, pp. 1363 - 1373
We report that Rcf1 (formerly Aim31), a member of the conserved hypoxia-induced gene 1 (Hig1) protein family, represents a novel component of the yeast... 
YEAST | OXYGEN | ORGANIZATION | RESPIRATORY-CHAIN | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | SUBUNIT-VIB | SACCHAROMYCES-CEREVISIAE | EXPRESSION | CELL BIOLOGY
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 46, pp. 13063 - 13068
Neurons depend on oxidative phosphorylation for energy generation, whereas astrocytes do not, a distinctive feature that is essential for neurotransmission and... 
Glycolysis | Redox | Brain | Bioenergetics | Lactate | RESPIRATORY-CHAIN | MULTIDISCIPLINARY SCIENCES | glycolysis | brain | KINETIC EVIDENCE | DEFICIENCY | redox | bioenergetics | METABOLISM | GLUTATHIONE | ANTIOXIDANT | GLUCOSE | NITRIC-OXIDE | lactate | PARKINSONS-DISEASE | Biological Sciences
Journal Article
BioFactors, ISSN 0951-6433, 09/2011, Volume 37, Issue 5, pp. 361 - 365
Journal Article
CELL CYCLE, ISSN 1538-4101, 02/2013, Volume 12, Issue 4, pp. 674 - 683
The term "mitochondrial permeability transition" (MPT) refers to an abrupt increase in the permeability of the inner mitochondrial membrane to low molecular... 
mitochondrial respiratory chain | CANCER-CELL DEATH | INDUCED APOPTOSIS | PORE COMPLEX | apoptosis | PHOSPHATE CARRIER | ATP5G1 | OUTER-MEMBRANE PERMEABILIZATION | p53 | CELL BIOLOGY | CYTOCHROME-C | CYCLOPHILIN-D | CYCLOSPORINE-A | permeability transition pore (PTP) | ENDOPLASMIC-RETICULUM | cytochrome c | caspases | GLUTAMATE EXCITOTOXICITY
Journal Article
Cell, ISSN 0092-8674, 09/2017, Volume 170, Issue 6, pp. 1247 - 1257.e12
The respiratory megacomplex represents the highest-order assembly of respiratory chain complexes, and it allows mitochondria to respond to energy-requiring... 
electron transfer pathway | megacomplex | cryo-EM | mitochondria | oxidative phosphorylation | human respiratory chain | CHAIN | CYTOCHROME-C-OXIDASE | COMPLEX-III | PROTEIN | SUPERCOMPLEX | RESPIRASOME | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BEAM-INDUCED MOTION | STABILIZES | ELECTRON-TRANSPORT | CELL BIOLOGY
Journal Article
Chemosphere, ISSN 0045-6535, 02/2020, Volume 241, p. 125099
Our previous study showed that excessive fluoride (F) intake can induce liver dysfunction. The aim of this study was to investigate the mechanisms of F-induced... 
Liver dysfunction | Mitochondrial fusion | Mitochondrial respiratory chain complex subunits | Fluoride | Mitochondrial
Journal Article
Journal Article
FRONTIERS IN NEUROANATOMY, ISSN 1662-5129, 07/2015, Volume 9, p. 91
Parkinson disease (PD) is a chronic, progressive neurological disease that is associated with a loss of dopaminergic neurons in the substantia nigra pars... 
NADPH OXIDASE | MICROGLIA-MEDIATED NEUROTOXICITY | RESPIRATORY-CHAIN DEFECTS | ANATOMY & MORPHOLOGY | Parkinson disease | mitochondrial dysfunction | ALPHA-SYNUCLEIN | DOPAMINERGIC-NEURONS | NEUROSCIENCES | PARS-COMPACTA | neuroinflammation | MITOCHONDRIAL COMPLEX-I | HUMAN SUBSTANTIA-NIGRA | LINKED GENE DJ-1 | dopamine | oxidative stress | PROTEIN DJ-1
Journal Article
Chemosphere, ISSN 0045-6535, 12/2019, Volume 237, p. 124548
The extensive application of radioactive element uranium (U) and its compounds in the nuclear industry has significantly increased the risk of exposure to the... 
Oxidative stress | Organism | Respiratory chain | Uranium | Chemical toxicity | Apoptosis
Journal Article
Diabetologia, ISSN 0012-186X, 9/2017, Volume 60, Issue 9, pp. 1577 - 1585
Metformin is a widely-used drug that results in clear benefits in relation to glucose metabolism and diabetes-related complications. The mechanisms underlying... 
Medicine & Public Health | Human Physiology | Metabolic Diseases | Internal Medicine | AMPK |