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Journal Article
Chemical Reviews, ISSN 0009-2665, 11/2018, Volume 118, Issue 21, pp. 10748 - 10773
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2008, Volume 105, Issue 39, pp. 15112 - 15117
Journal Article
Frontiers in Cellular Neuroscience, ISSN 1662-5102, 09/2018, Volume 12, pp. 316 - 316
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 6, pp. e11306 - e11306
Journal Article
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 09/2014, Volume 132, Issue 9, pp. 1043 - 1044
Journal Article
Current Biology, ISSN 0960-9822, 08/2015, Volume 25, Issue 16, pp. R713 - R715
Outer retinal degeneration is the leading cause of blindness in the developed world. A new study now demonstrates that ectopic expression of human rhodopsin in... 
RETINAL DEGENERATION | CELLS | MODELS | MELANOPSIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | RESTORATION | RESTORES VISUAL RESPONSES | GENE-TRANSFER | G(I/O) | EXPRESSION | CELL BIOLOGY | Animals | Rhodopsin - genetics | Ectopic Gene Expression | Humans | Retinal Degeneration - therapy | Rhodopsin | Blindness | Index Medicus
Journal Article
Molecular Therapy, ISSN 1525-0016, 11/2017, Volume 25, Issue 11, pp. 2546 - 2560
The majority of inherited retinal degenerations converge on the phenotype of photoreceptor cell death. Second- and third-order neurons are spared in these... 
visual restoration | retinitis pigmentosa | AAV | retinal gene therapy | optogenetics | MEDICINE, RESEARCH & EXPERIMENTAL | LIGHT RESPONSES | BLIND MICE | ON-BIPOLAR CELLS | RESTORES VISUAL RESPONSES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GANGLION-CELLS | GENETICS & HEREDITY | ECTOPIC EXPRESSION | GENE-THERAPY | CHANNELRHODOPSIN-2 | LEBERS CONGENITAL AMAUROSIS | PHOTORECEPTOR DEGENERATION | Dependovirus - genetics | Genetic Vectors - administration & dosage | Intravitreal Injections | Macaca fascicularis | Optogenetics | Retinal Ganglion Cells - metabolism | Channelrhodopsins - metabolism | Retinal Degeneration - metabolism | Recovery of Function | Retinal Ganglion Cells - pathology | Vision, Ocular - physiology | Light | Transgenes | Disease Models, Animal | Promoter Regions, Genetic | Gene Expression | Transduction, Genetic | Dependovirus - metabolism | Genetic Vectors - chemistry | Retinal Degeneration - genetics | Mice, Inbred C57BL | Genetic Vectors - metabolism | Mice, Transgenic | Channelrhodopsins - genetics | Animals | Retinal Degeneration - therapy | Mice | Photoreceptor Cells, Vertebrate - metabolism | Retinal Degeneration - pathology | Photoreceptor Cells, Vertebrate - pathology | Genetic Therapy - methods | Prostheses | Cytomegalovirus | Phenotypes | Recovery of function | Optics | Retina | Gene expression | Synuclein | Calcium permeability | Promoters | Visual perception | Studies | Retinal ganglion cells | Cell death | Information processing | Retinal degeneration | Illumination | Photoreceptors | Genetics | Mutation | Ganglion cells | Laboratory animals | Index Medicus | Life Sciences | Biotechnology | Human health and pathology | Sensory Organs | Original
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1221 - 12
Inherited and age-related retinal degenerative diseases cause progressive loss of rod and cone photoreceptors, leading to blindness, but spare downstream... 
OPTICAL CONTROL | RETINAL GANGLION-CELLS | BIPOLAR CELLS | LIGHT RESPONSES | BLIND MICE | MULTIDISCIPLINARY SCIENCES | ECTOPIC EXPRESSION | RESTORES VISUAL RESPONSES | RETINITIS-PIGMENTOSA | MOLECULAR-BASIS | PHOTORECEPTORS | Rhodopsin | Exploration | Retina | Vertebrates | Sensitivity | Restoration | Vision | Light | Blindness | Retinal degeneration | Photoreceptors | Retinitis | Kinetics | Age | Adaptation | Index Medicus
Journal Article