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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/2011, Volume 416, Issue 3-4, pp. 246 - 251
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 23, pp. 8518 - 8523
Progress in retinal-cell therapy derived from human pluripotent stem cells currently faces technical challenges that require the development of easy and... 
Epithelial cells | Induced pluripotent stem cells | Stem cells | Cell lines | Photoreceptors | Neural stem cells | Cultured cells | Pluripotent stem cells | Embryonic stem cells | Cellular differentiation | Cones | Retinal ganglion cells | Rods | DIRECTED DIFFERENTIATION | VESICLE-LIKE STRUCTURES | MULTIDISCIPLINARY SCIENCES | MOUSE | INDUCTION | FATE | PLURIPOTENT STEM-CELLS | cones | GROWTH | rods | retinal ganglion cells | GENERATION | EXPRESSION | REVEALS | Immunohistochemistry | Retinal Pigment Epithelium - metabolism | Homeodomain Proteins - metabolism | Humans | Multipotent Stem Cells - metabolism | Retinal Neurons - cytology | SOXB1 Transcription Factors - metabolism | Octamer Transcription Factor-3 - genetics | Transfection | SOXB1 Transcription Factors - genetics | Adult | Cell Differentiation | Cell Culture Techniques | Dermis - cytology | Induced Pluripotent Stem Cells - cytology | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Cell Line | Gene Expression | Nanog Homeobox Protein | Photoreceptor Cells - cytology | Cells, Cultured | Reverse Transcriptase Polymerase Chain Reaction | Homeodomain Proteins - genetics | Retinal Neurons - metabolism | Multipotent Stem Cells - cytology | Octamer Transcription Factor-3 - metabolism | Photoreceptor Cells - metabolism | Fibroblasts - cytology | Microscopy, Fluorescence | Retinal Pigment Epithelium - cytology | Physiological aspects | Retina | Tissue | Molecules | Cellular biology | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2010, Volume 107, Issue 1, pp. 75 - 80
Journal Article
Development (Cambridge), ISSN 0950-1991, 11/2013, Volume 140, Issue 22, pp. 4510 - 4521
Muller glia function as retinal stem cells in adult zebrafish. In response to loss of retinal neurons, Muller glia partially dedifferentiate, re-express... 
Müller glia | N-cadherin | Retinal regeneration | Alcama | Muller glia | STEM-CELLS | DEDIFFERENTIATION | PROLIFERATION | DEVELOPMENTAL BIOLOGY | GOLDFISH RETINA | ADULT ZEBRAFISH | VERTEBRATE RETINA | ROD PHOTORECEPTORS | SIGNALING PATHWAY | NEUROGENESIS | LINEAGE | Cadherins - metabolism | Multipotent Stem Cells - metabolism | Photoreceptor Cells, Vertebrate - drug effects | Ependymoglial Cells - metabolism | Neural Stem Cells - cytology | Neuroepithelial Cells - cytology | Retinal Ganglion Cells - metabolism | Retinal Neurons - cytology | Retinal Ganglion Cells - cytology | Neurogenesis - drug effects | Retinal Neurons - drug effects | Asymmetric Cell Division - drug effects | Ouabain - pharmacology | Biomarkers - metabolism | Cell Dedifferentiation - drug effects | Zebrafish Proteins - metabolism | Neural Stem Cells - drug effects | Photoreceptor Cells, Vertebrate - cytology | Cell Adhesion - drug effects | Ependymoglial Cells - drug effects | Regeneration - drug effects | Animals | Retinal Neurons - metabolism | Models, Biological | Multipotent Stem Cells - cytology | Zebrafish - metabolism | Ependymoglial Cells - cytology | Heterozygote | Neuroepithelial Cells - metabolism | Photoreceptor Cells, Vertebrate - metabolism | Cell Cycle - drug effects | Neural Stem Cells - metabolism | Retinal Ganglion Cells - drug effects | Index Medicus | Stem Cells and Regeneration
Journal Article
PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 12, pp. e8152 - e8152
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs).... 
PROGENITOR CELLS | MACULAR TRANSLOCATION | RCS RAT | SUBRETINAL TRANSPLANTATION | VISUAL FUNCTION | RPE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | AUTOLOGOUS TRANSPLANTATION | HUMAN FIBROBLASTS | PHOTORECEPTOR DEGENERATION | Biomarkers - metabolism | Epithelial Cells - transplantation | Immunohistochemistry | Cell Polarity | Photoreceptor Cells, Vertebrate - ultrastructure | Retinal Pigment Epithelium - transplantation | Cell Survival | Humans | Proto-Oncogene Proteins c-fos - metabolism | Retinal Diseases - therapy | Rats | Photoreceptor Cells, Vertebrate - cytology | Macrophages - cytology | Vision, Ocular - physiology | Animals | Retinal Pigment Epithelium - ultrastructure | Cell Shape | Retinal Diseases - pathology | Cell Differentiation | Epithelial Cells - cytology | Induced Pluripotent Stem Cells - cytology | Retinal Diseases - physiopathology | Phagocytosis | Retinal Pigment Epithelium - cytology | Macular degeneration | Epithelium | Embryonic stem cells | Health aspects | Monomolecular films | Transformation | Transcription factors | Pathogenesis | Embryo cells | Stem cell transplantation | Retina | Transplantation | Retinal pigment epithelium | Visual perception | Engineering | Allografts | Fibroblasts | Degeneration | Age | Medical personnel | Cell survival | Developmental biology | Medical treatment | Gene expression | Somatic cells | Stem cells | Photoreceptors | Pluripotency | Index Medicus
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 06/2017, Volume 141, Issue 5, pp. 750 - 765
The expression of the mRNAs of Nrf2‐related genes was increased in 661W cells after exposure to RS9. Nrf2 was detected in the nucleus of the 661W cells exposed... 
AMD | light‐induced retinal degeneration | Nrf2 | retina | photoreceptor | light-induced retinal degeneration | HO-1 | RETINAL DEGENERATION | OXIDATIVE STRESS | HUMAN-DISEASE | PROTECTION | BRAIN-INJURY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MACULAR DEGENERATION | NEUROSCIENCES | BLUE-LIGHT | NEUROPROTECTION | IN-VITRO | ISCHEMIA-REPERFUSION | RNA, Small Interfering - genetics | Cell Death - radiation effects | Cell Nucleolus - radiation effects | Heme Oxygenase-1 - metabolism | NF-E2 Transcription Factor - genetics | Triterpenes - pharmacology | Cytosol - drug effects | Ependymoglial Cells - radiation effects | Male | Retinal Degeneration - etiology | NF-E2 Transcription Factor - metabolism | Retinal Degeneration - prevention & control | Heme Oxygenase-1 - genetics | Triterpenes - chemistry | Retina - cytology | Time Factors | Cell Nucleolus - drug effects | Membrane Proteins - metabolism | Cell Death - drug effects | Protein Biosynthesis - radiation effects | Membrane Proteins - genetics | Light - adverse effects | RNA, Small Interfering - pharmacology | Ependymoglial Cells - drug effects | Photoreceptor Cells - radiation effects | Gene Expression Regulation - drug effects | Animals | Photoreceptor Cells - drug effects | Ependymoglial Cells - cytology | Gene Expression Regulation - radiation effects | Protein Biosynthesis - drug effects | Mice | Cytosol - radiation effects | In Vitro Techniques | Cell Line, Transformed | Neurochemistry | Chlorophyll | Oxidative stress | Enzymes | Heme oxygenase (decyclizing) | Retina | Oxygen consumption | Exposure | Nuclei | Environmental risk | Risk factors | Macular degeneration | Oxygenase | Cell death | Heme | Photoreceptors | Eye diseases | Degeneration | In vivo methods and tests | Nuclei (cytology) | Damage | In vitro methods and tests | Age | Apoptosis | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, pp. e109305 - e109305
We have investigated and compared the neurotrophic activity of human dental pulp stem cells (hDPSC), human bone marrow-derived mesenchymal stem cells (hBMSC)... 
SURVIVAL | OPTIC-NERVE | IN-VITRO | NEUROTROPHIC FACTOR | MULTIDISCIPLINARY SCIENCES | AXON REGENERATION | RATS | SPINAL-CORD | EXPERIMENTAL GLAUCOMA | BRAIN | TRANSPLANTATION | Nerve Growth Factor - secretion | Brain-Derived Neurotrophic Factor - secretion | Cell- and Tissue-Based Therapy - methods | Neuroprotection | Vascular Endothelial Growth Factor A - biosynthesis | Nerve Growth Factor - biosynthesis | Neurites - physiology | Coculture Techniques | Humans | Adipose Tissue - cytology | Male | Dental Pulp - metabolism | Retinal Ganglion Cells - metabolism | Vascular Endothelial Growth Factor A - secretion | Adipose Tissue - metabolism | Paracrine Communication - physiology | Retinal Ganglion Cells - cytology | Axotomy | Mesenchymal Stromal Cells - cytology | Brain-Derived Neurotrophic Factor - biosynthesis | Bone Marrow Cells - cytology | Dental Pulp - cytology | Mesenchymal Stromal Cells - metabolism | Rats | Rats, Sprague-Dawley | Animals | Primary Cell Culture | Bone Marrow Cells - metabolism | Fc receptors | Platelet-derived growth factor | Stem cells | Nerve growth factor | Comparative analysis | Ganglion | Vascular endothelial growth factor | Health aspects | Enzyme-linked immunosorbent assay | Neurosciences | Spinal cord | Mesenchyme | Neurobiology | Paracrine signalling | Stem cell transplantation | Retina | Nervous system | Neurotrophin 3 | Pulp | Receptors | Rodents | Bone marrow | Conditioning | Ganglion cells | Growth factors | Glial cell line-derived neurotrophic factor | Optic nerve | Cytokines | Axonogenesis | Dentistry | Gene expression | Survival | Medicine | Retinal ganglion cells | Brain research | Brain-derived neurotrophic factor | Inhibitors | Apoptosis | Dental pulp | Index Medicus
Journal Article
Acta Ophthalmologica, ISSN 1755-375X, 10/2016, Volume 94, Issue S256, p. n/a
  Purpose Muller cells are considered to be vital in the maintenance of retinal ganglion cells (RGCs), and since RGCs are essential to maintain the neuronal... 
Starvation | Cell survival | Homeostasis | Retina | Cultures | Circadian rhythm | Survival | Neuronal-glial interactions | Retinal ganglion cells | Inserts | Mice | Viability | Players
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2017, Volume 376, Issue 11, pp. 1038 - 1046
Journal Article