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01/2012
Recent evidences indicate that retinal muller cells exhibit retinal progenitor characteristics under certain condition in chick, rat and human. However, there... 
Rhesus monkey | Retinal stem cells | Muller cell | Retinal degenerative diseases
Web Resource
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ISSN 0146-0404, 11/2016, Volume 57, Issue 14, pp. 6278 - 6286
PURPOSE. Cluster of differentiation 40 (CD40) is required for retinal capillary degeneration in diabetic mice, a process mediated by the retinal endothelial... 
EXTRACELLULAR ATP | APOPTOSIS | ACTIVATION | ALPHA | Muller cells | DEGENERATION | RESPONSES | purinergic | INFLAMMATION | retinal endothelial cells | EXPERIMENTAL DIABETIC-RETINOPATHY | OPHTHALMOLOGY | MICROVASCULAR CELLS | P-2Z RECEPTOR
Journal Article
Experimental Eye Research, ISSN 0014-4835, 01/2018, Volume 166, pp. 91 - 95
The purpose of this study was to describe the distribution of Muller cell within the peripapillary retinal nerve fiber layer (RNFL) in human eyes. Eleven... 
Glial | Muller | Retinal nerve fiber layer | OPTICAL COHERENCE TOMOGRAPHY | NO LIGHT PERCEPTION | OPHTHALMOLOGY | THICKNESS | Immunohistochemistry | Index Medicus
Journal Article
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ISSN 0146-0404, 06/2014, Volume 55, Issue 6, pp. 3385 - 3394
PURPOSE. Alpha2-adrenergic receptor agonists are used in glaucoma treatment and have been shown to have some neuroprotective effects. We performed this study... 
RAS ACTIVATION | metalloproteinases | PROTEIN-COUPLED RECEPTORS | GROWTH-FACTOR RECEPTORS | FACTOR EXPRESSION | AGONISTS | Muller cells | transactivation | RETINAL GANGLION-CELLS | IN-VIVO | OPHTHALMOLOGY | EGF receptor | ALPHA-ADRENERGIC RECEPTORS | alpha2-adrenergic agonists | NEURAL REGENERATION | GLIA
Journal Article
Diabetes, ISSN 0012-1797, 09/2010, Volume 59, Issue 9, pp. 2297 - 2305
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 04/2017, Volume 58, Issue 4, pp. 1941 - 1953
PURPOSE. During retinal degeneration, Muller glia cells respond to photoreceptor loss by undergoing reactive gliosis, with both detrimental and beneficial... 
Müller cells | Retina | Hippo/YAP pathway | Photoreceptor degeneration | STEM-CELLS | HIPPO SIGNALING PATHWAY | ORGAN SIZE CONTROL | RAT RETINA | INTESTINAL REGENERATION | photoreceptor degeneration | RD10 MOUSE MODEL | Muller cells | TISSUE GROWTH-FACTOR | retina | OPHTHALMOLOGY | NEURAL REGENERATION | RETINITIS-PIGMENTOSA | TRANSCRIPTION FACTOR | Immunohistochemistry | Ependymoglial Cells - metabolism | Retinal Degeneration - metabolism | Photoreceptor Cells - pathology | Ependymoglial Cells - pathology | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Phosphoproteins - biosynthesis | Signal Transduction | Retinal Degeneration - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | Gene Expression Regulation | Transcription Factors - biosynthesis | Phosphoproteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Blotting, Western | Nuclear Proteins | Animals | Photoreceptor Cells - metabolism | Adaptor Proteins, Signal Transducing - genetics | Adaptor Proteins, Signal Transducing - biosynthesis | Mice | Retinal Degeneration - pathology | DNA-Binding Proteins - biosynthesis | Index Medicus | Neurons and Cognition | Psychology and behavior | Neurobiology | Photoreceptor Cells | Life Sciences | Adaptor Proteins, Signal Transducing | Retinal Degeneration | Phosphoproteins | Cognitive Sciences | Transcription Factors | RNA, Messenger | DNA-Binding Proteins | Ependymoglial Cells | YAP pathway | Retinal Cell Biology | Hippo
Journal Article
by Xue, B and Xie, YT and Xue, Y and Hu, N and Zhang, GW and Guan, HJ and Ji, M
EXPERIMENTAL EYE RESEARCH, ISSN 0014-4835, 12/2016, Volume 153, pp. 42 - 50
Muller cell reactivation (gliosis) is an early response in glaucomatous retina. Previous studies have demonstrated that activation of P2X(7) receptors results... 
Glaucoma | STIMULATION | VESICULAR GLUTAMATE | DEATH | INTRAOCULAR-PRESSURE | RELEASE | P2X receptor | EXPERIMENTAL GLAUCOMA | ASTROCYTES | Muller cell gliosis | GLIAL MULLER | NEURONS | OPHTHALMOLOGY | ATP | Retinal ganglion cell | Apoptosis
Journal Article
Journal Article
Journal Article
JOURNAL OF NEUROCHEMISTRY, ISSN 0022-3042, 02/2016, Volume 136, Issue 4, pp. 741 - 751
Muller cells, the primary macroglia of the retina, support various functions of retinal ganglion cells (RGCs). Here, we demonstrate a nucleotide-mediated... 
UDP | purinergic receptor | CENTRIFUGAL FORCE | ACTIVATION | glaucoma | BIOCHEMISTRY & MOLECULAR BIOLOGY | AQUEOUS-HUMOR | GLIAL-CELLS | NEUROSCIENCES | NEUROPROTECTION | FIBROBLASTS | glial cell | MICE | axon | ATP | EXPRESSION | retinal ganglion cell | GLAUCOMATOUS NEURODEGENERATION
Journal Article
by Jian, Q and Tao, Z and Li, YC and Yin, ZQ
VISION RESEARCH, ISSN 0042-6989, 05/2015, Volume 110, pp. 107 - 117
Our aim is to define related molecular events on how dormant Muller glia cells re-enter the cell cycle, proliferate and produce new retinal neurons from... 
Notch signaling pathway | RCS RATS | STEM-CELLS | ACTIVATION | AMACRINE CELLS | Acute retinal injury | Nerve growth factor | Muller cell | NEUROSCIENCES | DEGENERATION | Gliosis | Dedifferentiation | SODIUM IODATE | OPHTHALMOLOGY | ENDOGENOUS REPAIR | NEURAL REGENERATION | GLIA | RETINITIS-PIGMENTOSA
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 08/2017, Volume 58, Issue 10, pp. 4223 - 4234
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2012, Volume 32, Issue 45, pp. 15715 - 15727
Muller cells are the major glia of the retina that serve numerous functions essential to retinal homeostasis, yet the contribution of Muller glial dysfunction... 
IDIOPATHIC MACULAR TELANGIECTASIA | JUXTAFOVEOLAR RETINAL TELANGIECTASIS | DIABETIC-RETINOPATHY | FOCAL ASTROCYTE LOSS | CILIARY NEUROTROPHIC FACTOR | BLOOD-BRAIN-BARRIER | EXPRESSION | NEUROSCIENCES | INTRAOCULAR IMPLANTS | ENDOTHELIAL GROWTH-FACTOR | DEGENERATION
Journal Article