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science & technology (262) 262
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reverse transcriptase polymerase chain reaction (191) 191
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reverse gyrase (66) 66
gene expression (62) 62
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deoxyribonucleic acid--dna (33) 33
dna topoisomerase iv - genetics (33) 33
amino acid sequence (31) 31
fluoroquinolones (31) 31
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research article (30) 30
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science (19) 19
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topoisomerase (17) 17
biotechnology (16) 16
dna gyrase - metabolism (16) 16
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oligonucleotide array sequence analysis (16) 16
physiological aspects (16) 16
reverse transcriptase polymerase chain reaction - methods (16) 16
physical sciences (15) 15
rna, bacterial - genetics (15) 15
streptococcus pneumoniae - genetics (15) 15
bacterial diseases (14) 14
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1. Full Text Reverse gyrase is essential for microbial growth at 95 °C
by Lipscomb, Gina L and Hahn, Elin M and Crowley, Alexander T and Adams, Michael W. W and Univ. of Georgia, Athens, GA (United States)
Extremophiles : life under extreme conditions, ISSN 1431-0651, 05/2017, Volume 21, Issue 3, pp. 603 - 608
Pyrococcus furiosus | Hyperthermophile | Reverse gyrase | Archaea | Archaeal Proteins - metabolism | Pyrococcus furiosus - physiology | Extreme Environments | DNA Topoisomerases, Type I - metabolism | Cell Division | Gene Deletion | DNA Topoisomerases, Type I - genetics | Enzyme Stability | Archaeal Proteins - genetics | Hot Temperature | Pyrococcus furiosus - enzymology | Pyrococcus furiosus - genetics | Index Medicus | Space life sciences | Microbiology | Biochemistry & Molecular Biology
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2. Full Text A β-hairpin is a Minimal Latch that Supports Positive Supercoiling by Reverse Gyrase
by Collin, Frederic and Weisslocker-Schaetzel, Marine and Klostermeier, Dagmar
Journal of molecular biology, ISSN 0022-2836, 07/2020, Volume 432, Issue 16, pp. 4762 - 4771
topoisomerase | helicase | latch | positive DNA supercoiling | reverse gyrase | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Index Medicus
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3. Full Text The Evolution of Reverse Gyrase Suggests a Nonhyperthermophilic Last Universal Common Ancestor
by Catchpole, Ryan J and Forterre, Patrick
Molecular biology and evolution, ISSN 0737-4038, 12/2019, Volume 36, Issue 12, pp. 2737 - 2747
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Evolutionary Biology | Science & Technology | Gene Transfer, Horizontal | Origin of Life | Phylogeny | DNA Topoisomerases, Type I - genetics | Evolution, Molecular | Index Medicus | phylogeny | Discoveries | evolution | LUCA | hyperthermophiles | reverse gyrase
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4. Full Text Torsional stress in DNA limits collaboration among reverse gyrase molecules
by Ogawa, Taisaku and Sutoh, Kazuo and Kikuchi, Akihiko and Kinosita, Kazuhiko
The FEBS journal, ISSN 1742-464X, 04/2016, Volume 283, Issue 8, pp. 1372 - 1384
DNA overwinding | mismatched base pairs | torsional stress | reverse gyrase | DNA topoisomerase | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Hydrolysis | Biomechanical Phenomena | DNA Topoisomerases, Type I - metabolism | Sulfolobus - enzymology | Adenosine Triphosphate - metabolism | Base Sequence | DNA, Superhelical - chemistry | Cooperative Behavior | Models, Molecular | Molecular Sequence Data | Nucleic Acid Conformation | Sequence Homology, Nucleic Acid | Enzymes | DNA | Biophysics | Molecular biology | Deoxyribonucleic acid--DNA | Viscosity | Temperature requirements | Stress concentration | Energy consumption | Temperature | Torsional stress | Overwinding | Saturation | Base pairs | Hyperthermophiles | Bubbles | Friction | Microscopy | Energy | Temperature effects | Collaboration | Reverse gyrase | Acceleration | ATP | Index Medicus
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5. Full Text The reverse gyrase TopR1 is responsible for the homeostatic control of DNA supercoiling in the hyperthermophilic archaeon Sulfolobus solfataricus
by Couturier, Mohea and Gadelle, Danièle and Forterre, Patrick and Nadal, Marc and Garnier, Florence
Molecular microbiology, ISSN 0950-382X, 02/2020, Volume 113, Issue 2, pp. 356 - 368
DNA supercoiling | DNA topology | reverse gyrase | DNA topoisomerases | hyperthermophile | archaea | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Microbiology | Science & Technology | DNA biosynthesis | Temperature | Recombination | Transcription | Supercoiling | Topology | Reverse gyrase | High temperature | Deoxyribonucleic acid--DNA | Index Medicus
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6. Full Text Reverse gyrase functions in genome integrity maintenance by protecting DNA breaks in vivo
by Han, Wenyuan and Feng, Xu and She, Qunxin
International journal of molecular sciences, ISSN 1661-6596, 07/2017, Volume 18, Issue 7, p. 1340
MMS | Sulfolobus | Reverse gyrase | CRISPRi approach | Genomic DNA degradation | Genomic DNA breakage | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Archaeal Proteins - metabolism | DNA, Archaeal - genetics | Genomic Instability | DNA Topoisomerases, Type I - metabolism | Sulfolobus - enzymology | RNA, Messenger - genetics | DNA Topoisomerases, Type I - genetics | DNA, Archaeal - metabolism | Sulfolobus - genetics | CRISPR-Cas Systems | DNA Breaks | Archaeal Proteins - genetics | Sulfolobus - metabolism | Index Medicus | genomic DNA degradation | genomic DNA breakage | reverse gyrase
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7. Full Text Direct observation of positive supercoils introduced by reverse gyrase through atomic force microscopy
by Li, Dawei and Lv, Bei and wang, Qiang and Liu, Yun and Zhuge, Qiang
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 09/2017, Volume 27, Issue 17, pp. 4086 - 4090
Positive supercoil | DNA writhe | Reverse gyrases | AFM examination | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Microscopy, Atomic Force | DNA Topoisomerases, Type I - metabolism | DNA, Superhelical - biosynthesis | DNA Topoisomerases, Type I - chemistry | DNA, Superhelical - chemistry | Atomic force microscopy | Enzymes | Nucleases | Analysis | Microscope and microscopy | DNA | Forests and forestry | Index Medicus
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8. Full Text Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics
by Alt, Silke and Mitchenall, Lesley A and Maxwell, Anthony and Heide, Lutz
Journal of antimicrobial chemotherapy, ISSN 0305-7453, 9/2011, Volume 66, Issue 9, pp. 2061 - 2069
MICs | Supercoiling assays | Decatenation assays | Potassium glutamate | Pharmacology & Pharmacy | Infectious Diseases | Life Sciences & Biomedicine | Microbiology | Science & Technology | Infectious diseases | Bacterial diseases | Human bacterial diseases | Pharmacology. Drug treatments | Staphylococcal infections, streptococcal infections, pneumococcal infections | Biological and medical sciences | Medical sciences | Antibiotics. Antiinfectious agents. Antiparasitic agents | Aminocoumarins - pharmacology | Staphylococcus aureus - genetics | Staphylococcus aureus - enzymology | Escherichia coli - enzymology | Escherichia coli - drug effects | Structure-Activity Relationship | Reverse Transcriptase Polymerase Chain Reaction | Microbial Sensitivity Tests | Topoisomerase Inhibitors - pharmacology | DNA Gyrase - genetics | Escherichia coli - genetics | Anti-Bacterial Agents - chemistry | Topoisomerase II Inhibitors | Cloning, Molecular | DNA Topoisomerase IV - antagonists & inhibitors | DNA, Superhelical - chemistry | Glutamates - pharmacology | Anti-Bacterial Agents - pharmacology | Bacterial Proteins - biosynthesis | DNA Topoisomerase IV - genetics | Sodium Glutamate - pharmacology | Aminocoumarins - chemistry | Staphylococcus aureus - drug effects | Bacterial Proteins - isolation & purification | Enzymes | Staphylococcus infections | Antibiotics | E coli | Deoxyribonucleic acid--DNA | Index Medicus
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9. Full Text Transformation of a thermostable g-quadruplex structure into DNA duplex driven by reverse gyrase
by Li, Dawei and Wang, Qiang and Liu, Yun and Liu, Kun and Zhuge, Qiang and Lv, Bei
Molecules (Basel, Switzerland), ISSN 1420-3049, 11/2017, Volume 22, Issue 11, p. 2021
DNA supercoiling | Topoisomerase | Atomic Force Microscope examination | Topoisomer | G-quadruplex | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Thermodynamics | G-Quadruplexes | DNA - chemistry | Microscopy, Atomic Force - methods | DNA - metabolism | DNA Topoisomerases, Type I - metabolism | DNA structure | Atomic force microscopy | Transformation | Overwinding | Gel electrophoresis | Disintegration | DNA topoisomerase | Substrates | Hyperthermophiles | Microscopy | Reverse gyrase | Endonuclease | Atomic structure | Plasmid DNA | Deoxyribonucleic acid--DNA | Conformation | Index Medicus | topoisomerase | topoisomer
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10. Full Text Adenosine 5′-O-(3-thio)triphosphate (ATPγS) Promotes Positive Supercoiling of DNA by T. maritima Reverse Gyrase
by Jungblut, Stefan P and Klostermeier, Dagmar
Journal of molecular biology, ISSN 0022-2836, 2007, Volume 371, Issue 1, pp. 197 - 209
non-hydrolyzable ATP analog | topoisomerase | nucleotide-driven conformational changes | reverse gyrase | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Structure, Tertiary | Recombinant Proteins - metabolism | DNA Topoisomerases, Type I - metabolism | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | DNA Topoisomerases, Type I - chemistry | DNA Topoisomerases, Type I - genetics | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Thermotoga maritima - genetics | Nucleotides - metabolism | Plasmids - metabolism | Thermotoga maritima - enzymology | Adenosine Triphosphate - analogs & derivatives | Adenosine Triphosphate - metabolism | DNA, Superhelical - chemistry | Plasmids - genetics | Bacterial Proteins - metabolism | Mutation | DNA, Superhelical - metabolism | Nucleic Acid Conformation | Bacterial Proteins - isolation & purification | DNA Topoisomerases, Type I - isolation & purification | Index Medicus
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11. Full Text Crystal structures of Thermotoga maritima reverse gyrase: Inferences for the mechanism of positive DNA supercoiling
by Rudolph, Markus G and Del Toro Duany, Yoandris and Jungblut, Stefan P and Ganguly, Agneyo and Klostermeier, Dagmar
Nucleic acids research, ISSN 0305-1048, 01/2013, Volume 41, Issue 2, pp. 1058 - 1070
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Structure, Tertiary | DNA Helicases - chemistry | Zinc Fingers | DNA Topoisomerases, Type I - metabolism | Bacterial Proteins - chemistry | DNA Topoisomerases, Type I - chemistry | Models, Molecular | Crystallography, X-Ray | Thermotoga maritima - enzymology | DNA, Superhelical - chemistry | Bacterial Proteins - metabolism | DNA, Superhelical - metabolism | Binding Sites | Index Medicus | DNA helicase | DNA-binding protein | Molecular modelling | reverse gyrase | Cooperation | DNA | hyperthermophilic archaea | DNA topoisomerase | Supercoiling | Catalysis | Zinc finger proteins | Crystal structure | Nucleic Acid Enzymes
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